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Cardiology / Review
Update on heart failure management and future directions
[corrected-article]
Hong-Mi Choi, Myung-Soo Park, Jong-Chan Youn
Korean J Intern Med. 2019;34(1):11-43. Published online December 28, 2018
Heart failure (HF) is an important cardiovascular disease because of its increasing prevalence, significant morbidity, high mortality, and rapidly expanding health care cost. The number of HF patients is increasing worldwide, and Korea is no exception. There have been marked advances in definition, ..
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Rheumatology / Original Article
Red blood cell distribution width is useful in discriminating adult onset Still’s disease and sepsis within 24 hours after hospitalization
Hee-Jin Park, Jungsik Song, Yong-Beom Park, Soo-Kon Lee, Sang-Won Lee
Korean J Intern Med. 2018;33(6):1234-1240. Published online August 25, 2017
Background/Aims: Red blood cell distribution width (RDW) is a value representing the heterogeneity in the size of red blood cell, and it is usually used in distinguishing types of anaemia. Recently, it was reported that it could reflect the burden of inflammation in diverse diseases and their progno..
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Infectious diseases / Review
Vibrio vulnificus infection: a persistent threat to public health
Na Ra Yun, Dong-Min Kim
Korean J Intern Med. 2018;33(6):1070-1078. Published online June 15, 2018
Vibrio vulnificus is a gram-negative bacterium that can cause serious, potentially fatal infections. V. vulnificus causes three distinct syndromes: an overwhelming primary septicemia caused by consuming contaminated seafood, wound infections acquired when an open wound is exposed to contaminated war..
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Infectious diseases / Original Article
Late diagnosis of influenza in adult patients during a seasonal outbreak
Seong-Ho Choi, Jin-Won Chung, Tark Kim, Ki-Ho Park, Mi Suk Lee, Yee Gyung Kwak
Korean J Intern Med. 2018;33(2):391-396. Published online November 10, 2017
Background/Aims: Due to advances in diagnostic techniques, clinicians are more frequently performing influenza diagnostic tests and referring to their test results ahead of the administration of neuraminidase inhibitors (NAIs). To investigate the clinical significance of the time from symptom onset ..
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Infectious diseases / Original Article
Diagnostic role of mean platelet volume and neutrophil to lymphocyte ratio in childhood brucellosis
Şefika Elmas Bozdemir, Yasemin Ay Altıntop, Salih Uytun, Humeyra Aslaner, Yasemin Altuner Torun
Korean J Intern Med. 2017;32(6):1075-1081. Published online December 14, 2016
Background/Aims: Brucellosis patients present various non-specific clinical symptoms, such as fever, fatigue, sweating, joint pain, arthritis, myalgia, and headache. Based on the nonspecifity of its clinical signs and symtoms, we decided to evaluate whether mean platelet volume (MPV) , neutrophil to..
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Rheumatology / Original Article
Impact of early diagnosis on functional disability in rheumatoid arthritis
Dam Kim, Chan-Bum Choi, Jiyoung Lee, Soo-Kyung Cho, Soyoung Won, So-Young Bang, Hoon-Suk Cha, Jung-Yoon Choe, Won Tae Chung, Seung-Jae Hong, Jae-Bum Jun, Young Ok Jung, Jinseok Kim, Seong-Kyu Kim, Tae-Hwan Kim, Tae-Jong Kim, Eunmi Koh, Hye-Soon Lee, Jaejoon Lee, Jisoo Lee, Sang-Heon Lee, Shin-Seok Lee, Sung Won Lee, Seung-Cheol Shim, Dae-Hyun Yoo, Bo Young Yoon, Yoon-Kyoung Sung, Sang-Cheol Bae; KORONA investigators
Korean J Intern Med. 2017;32(4):738-746. Published online September 13, 2016
Background/Aims: To determine whether early diagnosis is beneficial for functional status of various disease durations in rheumatoid arthritis (RA) patients.
Methods: A total of 4,540 RA patients were enrolled as part of the Korean Observational Study Network for Arthritis (KORONA). We defined earl..
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Hemato-oncology / Review
Recent advances in multiple myeloma: a Korean perspective
Junshik Hong, Jae Hoon Lee
Korean J Intern Med. 2016;31(5):820-834. Published online September 1, 2016
Epidemiologically, multiple myeloma (MM) is a malignant disorder of plasma cells with a higher incidence among Western populations than among Asians. However, there is growing evidence of a recent increase in the age-standardized incidence rate (ASR) of MM in Asian countries, particularly Korea. App..
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Pulmonology / Original Article
Neuron-specific enolase as a novel biomarker reflecting tuberculosis activity and treatment
response
Sung-Jin Nam, Jee-Yeong Jeong, Tae-Won Jang, Mann-Hong Jung, Bong-Kwon Chun, Hee-Jae Cha, Chul-Ho Oak
Korean J Intern Med. 2016;31(4):694-702. Published online June 3, 2016
Background/Aims: It is not clear which tests are indicative of the activity and severity of tuberculosis (TB). This study aimed to investigate the predictive value of neuron-specific enolase (NSE) and to determine the origin of NSE in TB patients.
Methods: A single-center retrospective analysis was..
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Etc. / Original Article
The Korean version of the FRAIL scale: clinical feasibility and validity of assessing the frailty status of Korean elderly
Hee-Won Jung, Hyun-Jung Yoo, Si-Young Park, Sun-Wook Kim, Jung-Yeon Choi, Sol-Ji Yoon, Cheol-Ho Kim, Kwang-il Kim
Korean J Intern Med. 2016;31(3):594-600. Published online December 23, 2015
Background/Aims: The fatigue, resistance, ambulation, illnesses, and loss of weight (FRAIL) scale is a screening tool for frailty status using a simple 5-item questionnaire. The aim of this study was to evaluate the clinical feasibility and validity of the Korean version of the FRAIL (K-FRAIL) scale..
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Gastroenterology / Original Article
Diagnostic value of alcoholic liver disease (ALD)/nonalcoholic fatty liver disease (NAFLD) index combined with γ-glutamyl transferase in differentiating ALD and NAFLD
Junling Wang, Ping Li, Zhilong Jiang, Qiuhui Yang, Yuqiang Mi, Yonggang Liu, Ruifang Shi, Yonghe Zhou, Jinsheng Wang, Wei Lu, Si Li, Dan Liu
Korean J Intern Med. 2016;31(3):479-487. Published online March 30, 2016
Background/Aims: This study aimed to verify the reliability of the alcoholic liver disease (ALD)/nonalcoholic fatty liver disease (NAFLD) index (ANI) for distinguishing ALD in patients with hepatic steatosis from NAFLD, and to investigate whether ANI combined with γ-glutamyl transferase (GGT) woul..
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Gastroenterology / Original Article
Feasibility of α-fetoprotein as a diagnostic tool for hepatocellular carcinoma in Korea
Dae Geon Ahn, Hyung Joon Kim, Hyun Kang, Hyun Woong Lee, Si Hyun Bae, Joon Hyoek Lee, Yong Han Paik, June Sung Lee
Korean J Intern Med. 2016;31(1):46-53. Published online December 28, 2015
Background/Aims: The aim of this study was to evaluate the feasibility of α-fetoprotein (AFP) as a diagnostic tool for hepatocellular carcinoma (HCC) in Korean patients.
Methods: We retrospectively reviewed the medical records of HCC and cirrhosis patients at three hospitals. For each HCC patient..
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Gastroenterology / Original Article
Clinical characteristics and the usefulness of the QuantiFERON-TB Gold In-Tube test in hematologic patients with hepatic or splenic lesions
Jae-Cheol Kwon, Si-Hyun Kim, Sun Hee Park, Su-Mi Choi, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo, Yoo-Jin Kim, Seok Lee, Hee-Je Kim, Seok-Goo Cho, Jong-Wook Lee, Woo-Sung Min
Korean J Intern Med. 2013;28(2):187-196. Published online February 27, 2013
Background/AimsHepatic or splenic lesions in hematologic patients are not defined well because they are not easy to evaluate due to limitations of invasive procedures. Management typically depends on the clinical diagnosis with few microbiological data. Me.. </div>
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<div style="color:#C62F37;font-family:'Noto Sans KR', 'Nanum Gothic', sans-serif;">Review </div>
<a class="artiletitle" href="/journal/view.php?number=162624" onmouseover="showAbstract('162624' );" onmouseout="hideAbstract('162624' );"><b><font>Recent Paradigm Shifts in the Diagnosis and Treatment of Rheumatoid Arthritis</font></b></a>
<div style="padding-top:2px;padding-left:0px" class="article_authors">Young Ok Jung, Hyun Ah Kim</div>
<div style="padding-top:2px;padding-left:0px" class="article_issue">
<em>Korean J Intern Med.</em> 2012;27(4):378-387. Published online November 27, 2012 </div>
<div class="doi">DOI: <a href="https://doi.org/10.3904/kjim.2012.27.4.378"><font class="doi">https://doi.org/10.3904/kjim.2012.27.4.378</font></a>
<a href="/journal/CitedByRenew.php?number=162624" onclick="window.open(this.href, 'CrossRef Citedby', 'width=800,height=800,scrollbars=yes');return false;" style="color:#DD434F;font-size:10pt;"> Crossref 14</a>
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<a href='/journal/view.php?number=162624' style='text-decoration:underline;color:#2046f8'><img src='/image/button/fulltext.gif' alt='Full Text' /></a> <a href='/journal/view.php?viewtype=pubreader&number=162624' style='text-decoration:underline;color:#2046f8'><img src='/image/button/pubreader.gif' alt='PubReader' /></a> <a style='cursor: pointer;' onclick='journal_download("epub", "162624", "path=L2hvbWUvdmlydHVhbC9rYWltL2pvdXJuYWwvdXBsb2FkL2VwdWIva2ppbS0yNy0zNzguZXB1Yg==&filename=a2ppbS0yNy0zNzguZXB1Yg==")'><img src='/image/button/epub.gif' alt='ePub' /></a> <a style='cursor: pointer;' onclick='journal_download("pdf", "162624", "kjim-27-378.pdf")'><img src='/image/button/pdf.gif' alt='PDF' /></a> </div>
<div id="162624" style="display:none;padding-top:10px;padding-left:0px; color:#7b7b7b">
<p>Rheumatoid arthritis (RA) is a progressive inflammatory disease with severe symptoms of pain and stiffness. Chronic persistent inflammation of RA often leads to joint destruction, deformity and limitation of function, which ultimately results in significant deterioration of quality of life (QoL)... </div>
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<div style="color:#C62F37;font-family:'Noto Sans KR', 'Nanum Gothic', sans-serif;">Original Article </div>
<a class="artiletitle" href="/journal/view.php?number=162561" onmouseover="showAbstract('162561' );" onmouseout="hideAbstract('162561' );"><b><font>Validity of Glycated Hemoglobin in Screening and Diagnosing Type 2 Diabetes Mellitus in Chinese Subjects</font></b></a>
<div style="padding-top:2px;padding-left:0px" class="article_authors">Yun Yu, Xiao-Jun Ouyang, Qing-Lin Lou, Liu-Bao Gu, Yong-Zhen Mo, Gary T. Ko, Chun-Chung Chow, Wing-Yee So, Ronald Ma, Alice Kong, Nicola Brown, Jennifer Nan, Juliana Chan, Rong-Wen Bian</div>
<div style="padding-top:2px;padding-left:0px" class="article_issue">
<em>Korean J Intern Med.</em> 2012;27(1):41-46. Published online February 28, 2012 </div>
<div class="doi">DOI: <a href="https://doi.org/10.3904/kjim.2012.27.1.41"><font class="doi">https://doi.org/10.3904/kjim.2012.27.1.41</font></a>
<a href="/journal/CitedByRenew.php?number=162561" onclick="window.open(this.href, 'CrossRef Citedby', 'width=800,height=800,scrollbars=yes');return false;" style="color:#DD434F;font-size:10pt;"> Crossref 13</a>
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<div class="etc" style="padding-top:5px;text-align: right;">
<a href='/journal/view.php?number=162561' style='text-decoration:underline;color:#2046f8'><img src='/image/button/fulltext.gif' alt='Full Text' /></a> <a href='/journal/view.php?viewtype=pubreader&number=162561' style='text-decoration:underline;color:#2046f8'><img src='/image/button/pubreader.gif' alt='PubReader' /></a> <a style='cursor: pointer;' onclick='journal_download("epub", "162561", "path=L2hvbWUvdmlydHVhbC9rYWltL2pvdXJuYWwvdXBsb2FkL2VwdWIva2ppbS0yNy00MS5lcHVi&filename=a2ppbS0yNy00MS5lcHVi")'><img src='/image/button/epub.gif' alt='ePub' /></a> <a style='cursor: pointer;' onclick='journal_download("pdf", "162561", "kjim-27-41.pdf")'><img src='/image/button/pdf.gif' alt='PDF' /></a> </div>
<div id="162561" style="display:none;padding-top:10px;padding-left:0px; color:#7b7b7b">
<sec><title>Background/AimsThe application of glycated hemoglobin (HbA1c) for the diagnosis of diabetes is currently under extensive discussion. In this study, we explored the validity of using HbA1c as a screening and diagnostic test in Chinese subjects recruited in..
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Original Article
Early Detection Of Asymptomatic Coronary Artery Disease In Patients With Type 2 Diabetes Mellitus
Won Sang Yoo, Hee Jin Kim, Dohee Kim, Myung Yong Lee, Hyun-Kyung Chung
Korean J Intern Med. 2009;24(3):183-189. Published online August 26, 2009
Background/AimsIn type 2 diabetic patients, coronary artery disease (CAD) is usually detected at an advanced stage due to a lack of symptoms. The aim of this study was to define which clinical parameters or non-invasive tests predict CAD in asymptomatic type 2 diabetic patients..
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