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Endocrinology-metabolism / Original Article
The clinical meaning of pre- and post-ablation thyroglobulin levels at first radioiodine therapy in patients with papillary thyroid cancer
Hee Kyung Kim, Jee Hee Yoon, Jin Seong Cho, Seong Young Kwon, Su Woong Yoo, Ho-Cheol Kang
Korean J Intern Med. 2020;35(5):1164-1172. Published online July 29, 2019
Background/Aims: This study was conducted to identify prognostic factors in patients with papillary thyroid cancer (PTC) at the time of first radioactive iodine (RAI) therapy, and to evaluate the clinical value of the thyroglobulin (Tg) increase after RAI.
Methods: Serum Tg was sampled prior to (pr..
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Cardiology / Original Article
Hydrochlorothiazide use and the risk of skin cancer in patients with hypertensive disorder: a nationwide retrospective cohort study from Korea
Eunjung Park, Young Lee, Mihn-Sook Jue
Korean J Intern Med. 2020;35(4):917-928. Published online December 18, 2019
Background/Aims: Recent studies have shown a cumulative dose-dependent association between the use of hydrochlorothiazide (HCTZ) and skin cancer, including melanoma and non-melanoma skin cancer (NMSC) in Western Europe. However, whether this pattern is present in East Asia countries is unknown. The ..
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Hemato-oncology / Original Article
Metabolic comorbidities and medical institution utilization among breast cancer survivors: a national population-based study
Jaesung Heo, Mison Chun, Young-Taek Oh, O Kyu Noh, Logyoung Kim
Korean J Intern Med. 2020;35(2):421-428. Published online September 5, 2019
Background/Aims: We investigated metabolic comorbidity status and patterns of medical institution utilization among breast cancer survivors using medical claims data from the Health Insurance Review and Assessment Service (HIRA).
Methods: Using claims data obtained from the HIRA, we selected breast..
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Review
Evaluating the recent developments in palliative chemotherapy for metastatic colorectal cancer
Sun Kyung Baek, Kyu Taek Lee, Sang Byung Bae, Sang-Cheol Lee
Korean J Intern Med. 2019;34(6):1188-1196. Published online July 29, 2019
The incidence of colorectal cancer (CRC) has increased. CRC is the third most common cancer and the fourth most common cause of cancer-related deaths in Korea. Palliative chemotherapy can be used to shrink tumors and ease symptoms caused by the cancer when cure is not possible. It is important to id..
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Endocrinology-metabolism / Original Article
Utility of shear wave elastography to detect papillary thyroid carcinoma in thyroid nodules: efficacy of the standard deviation elasticity
Hye Jeong Kim, Mi Kyung Kwak, In Ho Choi, So-Young Jin, Hyeong Kyu Park, Dong Won Byun, Kyoil Suh, Myung Hi Yoo
Korean J Intern Med. 2019;34(4):850-857. Published online February 23, 2018
Background/Aims: The aim of this study was to address the role of the elasticity index as a possible predictive marker for detecting papillary thyroid carcinoma (PTC) and quantitatively assess shear wave elastography (SWE) as a tool for differentiating PTC from benign thyroid nodules.
Methods: One ..
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Gastroenterology / Original Article
Current status of endoscopic submucosal dissection for early gastric cancer in Korea: role and benefits
Sang Gyun Kim, Da Hyun Lyu, Chan Mi Park, Na Rae Lee, Jiyoung Kim, Youngju Cha, Hwoon-Yong Jung
Korean J Intern Med. 2019;34(4):785-793. Published online June 21, 2018
Background/Aims: This study was aimed to investigate the current clinical status of endoscopic submucosal dissection (ESD) for early gastric cancer (EGC) in Korea based on a National Health Insurance (NHI) database between 2011 and 2014.
Methods: The claims data of ESD for EGC in Korean NHI were re..
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Rheumatology / Original Article
Risk of malignancy in patients with rheumatoid arthritis after anti-tumor necrosis factor therapy: results from Korean National Health Insurance claims data
Seung Min Jung, Seung-Ki Kwok, Ji Hyeon Ju, Yong-Beom Park, Sung-Hwan Park
Korean J Intern Med. 2019;34(3):669-677. Published online November 29, 2017
Background/Aims: Inhibition of tumor necrosis factor (TNF) is an effective treatment for rheumatoid arthritis (RA), but safety concerns about malignancy remain. The aim of this study was to evaluate cancer risk in RA patients treated with TNF inhibitors (TNFi), based on Korean Nationwide Health Insu..
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Hemato-oncology / Original Article
Comparison of the morphologic criteria (RECIST) and metabolic criteria (EORTC and PERCIST) in tumor response assessments: a pooled analysis
Hong Deok Kim, Bum Jun Kim, Hyeong Su Kim, Jung Han Kim
Korean J Intern Med. 2019;34(3):608-617. Published online January 17, 2018
Background/Aims: The Positron Emission Tomography Response Criteria in Solid Tumors (PERCIST) or European Organization for Research and Treatment of Cancer (EORTC) criteria are used to assess metabolic tumor responses. However, tumor responses have shown considerable discrepancies between the morpho..
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Gastroenterology / Original Article
Effect of Helicobacter pylori eradication on the regression of gastric polyps in National Cancer Screening Program
Su Youn Nam, Bum Joon Park, Kum Hei Ryu, Ji Hyung Nam
Korean J Intern Med. 2018;33(3):506-511. Published online December 14, 2017
Background/Aims: Western guidelines recommend Helicobacter pylori eradication in H. pylori-associated gastric polyps; however, there is no standard guideline in Korea. The aim of this study is to assess the effect of H. pylori eradication on the regression of gastric hyperplasti..
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Letter to the editor
Synchronous parathyroid carcinoma and papillary thyroid carcinoma in a patient with long-standing schizophrenia
Cho-Ok Baek, Ki Hoi Kim, Sun Kyung Song
Korean J Intern Med. 2017;32(6):1104-1107. Published online October 17, 2017
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Pulmonology / Review
The role of hypoxia on the acquisition of epithelial-mesenchymal transition and cancer stemness: a possible link to epigenetic regulation
Chang Dong Yeo, Nahyeon Kang, Su Yeon Choi, Bit Na Kim, Chan Kwon Park, Jin Woo Kim, Young Kyoon Kim, Seung Joon Kim
Korean J Intern Med. 2017;32(4):589-599. Published online June 30, 2017
A hypoxic microenvironment leads to cancer progression and increases the metastatic potential of cancer cells within tumors via epithelial-mesenchymal transition (EMT) and cancer stemness acquisition. The hypoxic response pathway can occur under oxygen tensions of < 40 mmHg through hypoxia-inducible..
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Gastroenterology / Review
Roadmap for elimination of gastric cancer in Korea
David Y. Graham
Korean J Intern Med. 2015;30(2):133-139. Published online February 27, 2015
Most gastric cancers are caused by infection with the common human bacterial pathogen, Helicobacter pylori. It is now accepted that gastric cancer can be prevented and virtually eliminated by H. pylori eradication and this knowledge was responsible for country-wide H. pylori era..
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Endocrinology-metabolism / Original Article
Follicular and Hurthle cell carcinoma of the thyroid in iodine-sufficient area: retrospective analysis of Korean multicenter data
Won Gu Kim, Tae Yong Kim, Tae Hyuk Kim, Hye Won Jang, Young Suk Jo, Young Joo Park, Sun Wook Kim, Won Bae Kim, Minho Shong, Do Joon Park, Jae Hoon Chung, Young Kee Shong, Bo Youn Cho
Korean J Intern Med. 2014;29(3):325-333. Published online April 29, 2014
Background/Aims: Follicular thyroid carcinoma (FTC) and Hurthle cell carcinoma (HCC) of the thyroid are relatively uncommon thyroid malignancies in iodine- sufficient areas. In this study we evaluated the clinical behavior, prognostic factors and treatment outcomes of FTC and HCC in Korea.
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Hemato-oncology / Original Article
Third-line docetaxel chemotherapy for recurrent and metastatic gastric cancer
Ji Hyun Lee, Sung-Hyun Kim, Sung Yong Oh, Suee Lee, Hojin Lee, Hye Jung Lee, Hyo-Jin Kim
Korean J Intern Med. 2013;28(3):314-321. Published online May 1, 2013
Background/AimsTo determine the efficacy and toxicity of docetaxel as a third-line therapy for patients with relapsed gastric cancer who have undergone modified oxaliplatin-fluorouracil (m-FOLFOX)-4 and modified irinotecan-fluorouracil (m-FOLFIRI) regimens.
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Case Report
Case of concurrent Riedel's thyroiditis, acute suppurative thyroiditis, and micropapillary carcinoma
Ji Taek Hong, Jung Hwan Lee, So Hun Kim, Seong Bin Hong, Moonsuk Nam, Yong Seong Kim, Young Chae Chu
Korean J Intern Med. 2013;28(2):236-241. Published online February 27, 2013
Riedel's thyroiditis (RT) is a rare chronic inflammatory disease of the thyroid gland. It is characterized by a fibroinflammatory process that partially destroys the gland and extends into adjacent neck structures. Its clinical manifestation can mask an accompanying thyroid neoplasm and can mimic..
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Letter to the editor
Parathyroid Carcinoma Presenting as a Hyperparathyroid Crisis
Alice Hyun-Kyung Tan, Hee Kyung Kim, Mi Yeon Kim, Young Lyun Oh, Jee Soo Kim, Jae Hoon Chung, Sun Wook Kim
Korean J Intern Med. 2012;27(2):229-231. Published online May 31, 2012
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Original Article
Prognostic Factors Associated with Survival in Patients with Primary Duodenal Adenocarcinoma
Woo Chul Chung, Chang Nyol Paik, Sung Hoon Jung, Kang-Moon Lee, Sang Woo Kim, U-Im Chang, Jin Mo Yang
Korean J Intern Med. 2011;26(1):34-40. Published online March 2, 2011
Background/AimsThe prognostic factors in primary duodenal adenocarcinoma remain controversial. This study evaluated the prognostic factors associated with survival in patients with primary duodenal adenocarcinoma. MethodsFrom March 1996 to June ..
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Original Article
Microarray Analysis of Papillary Thyroid Cancers in Korean
Hyun Sook Kim, Do Hyung Kim, Ji Yeon Kim, Nam Ho Jeoung, In Kyu Lee, Jin Gu Bong, Eui Dal Jung
Korean J Intern Med. 2010;25(4):399-407. Published online November 27, 2010
Background/AimsPapillary thyroid cancer (PTC) is the most common malignancy of the thyroid gland. It involves several molecular mechanisms. The BRAF V600E mutation has been identified as the most common genetic abnormality in PTC. Moreover, it is known to be m..
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Case Report
Successful Treatment of Small-Cell Lung Cancer With Irinotecan in a Hemodialysis Patient With End-Stage Renal Disease
Dong Min Kim, Hyun Lee Kim, Choon Hae Chung, Chi Young Park
Korean J Intern Med. 2009;24(1):73-75. Published online March 6, 2009
The prognosis of patients with end-stage renal disease has improved with advances in hemodialysis techniques. However, many patients who undergo hemodialysis suffer from various types of cancer. Limited data is available to guide clinical management of these patients who may have impaired renal f..
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Original Article
EGFR and KRAS Mutations in Patients With Adenocarcinoma of the Lung
Tae Won Jang, Chul Ho Oak, Hee Kyung Chang, Soon Jung Suo, Mann Hong Jung
Korean J Intern Med. 2009;24(1):48-54. Published online March 6, 2009
Background/AimsMutations of the epidermal growth factor receptor (EGFR) and Kirsten rat sarcoma viral oncogene (KRAS) are important in the pathogenesis of lung cancer, and recent reports have revealed racial and geographical differences in mutation expression.
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