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Pulmonology / Original Article
Effects of adjunctive dobutamine on outcomes among patients with septic shock: a propensity score matching analysis
Sung Yoon Lim, Kyu Jin Lee, Yeonhoon Jang, Yeon Joo Lee, Ryoung-Eun Ko, Gee Young Suh, Dong Kyu Oh, Su Yeon Lee, Mi Hyeon Park, Chae-Man Lim, Sunghoon Park; on behalf of the Korean Sepsis Alliance (KSA) investigators
Korean J Intern Med. 2025;40(6):990-1001. Published online October 31, 2025
Background/Aims: Despite some evidence supporting its utility, the role of adjunctive dobutamine in the management of septic shock remains unclear.
Methods: The nationwide prospective sepsis cohort of the Korean Sepsis Alliance was analyzed. Adult patients with septic shock receiving norepinephrine..
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Pulmonology / Original Article
Pulse pressure during the initial resuscitative period in patients with septic shock treated with a protocol-driven resuscitation bundle therapy
Sang-Hun Lee, Youn-Jung Kim, Gi Na Yu, Jae Cheon Jeon, Won Young Kim
Korean J Intern Med. 2021;36(4):924-931. Published online August 20, 2020
Background/Aims: Maintaining a mean arterial pressure (MAP) ≥ 65 mmHg during septic shock should be based on individual circumstances, but specific target is poorly understood. We investigated associations between time-weighted average (TWA) hemodynamic parameters during the initial resuscitative ..
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Original Article / Brief Communication
Clinical characteristics of coronavirus disease 2019 patients with diarrhea in Daegu
Min Kyu Kang, Kyeong Ok Kim, Min Cheol Kim, Joon Hyun Cho, Sung Bum Kim, Jung Gil Park, Kook Hyun Kim, See Hyung Lee, Byung Ik Jang, Tae Nyeun Kim
Korean J Intern Med. 2020;35(6):1261-1269. Published online September 23, 2020
Background/Aims: Coronavirus disease 2019 (COVID-19) can reportedly cause gastrointestinal symptoms. Therefore, we investigated the clinical characteristics of COVID-19 patients with diarrhea.
Methods: We included 118 COVID-19 patients admitted to a single hospital from February 20 to March 31, 202..
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Infectious diseases / Original Article
Cancer patients with neutropenic septic shock: etiology and antimicrobial resistance
Sung Min Jung, Youn Jung Kim, Seung Mok Ryoo, Chang Hwan Sohn, Dong Woo Seo, Kyoung Soo Lim, Won Young Kim
Korean J Intern Med. 2020;35(4):979-987. Published online October 28, 2019
Background/Aims: Among patients with febrile neutropenia that developed after chemotherapy, high-risk patients, such as those having clinical instability or Multinational Association of Supportive Care in Cancer score of < 21, require hospitalization for intravenous empiric antibiotic therapy. Mono..
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Pulmonology / Original Article
A combination of early warning score and lactate to predict intensive care unit transfer of inpatients with severe sepsis/septic shock
Jung-Wan Yoo, Ju Ry Lee, Youn Kyung Jung, Sun Hui Choi, Jeong Suk Son, Byung Ju Kang, Tai Sun Park, Jin-Won Huh, Chae-Man Lim, Younsuck Koh, Sang Bum Hong
Korean J Intern Med. 2015;30(4):471-477. Published online June 29, 2015
Background/Aims: The modified early warning score (MEWS) is used to predict patient intensive care unit (ICU) admission and mortality. Lactate (LA) in the blood lactate (BLA) is measured to evaluate disease severity and treatment efficacy in patients with severe sepsis/septic shock. The usefulness o..
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Case Report
Skin Necrosis after a Low-Dose Vasopressin Infusion through a Central Venous Catheter for Treating Septic Shock
Eun Hee Kim, Sae Hwan Lee, Seung Woon Byun, Ho Suk Kang, Dong Hoe Koo, Hyun-Gu Park, Sang Bum Hong
Korean J Intern Med. 2006;21(4):287-290. Published online December 31, 2006
This is a report on a case of severe skin necrosis in a vasodilatory septic shock patient after the infusion of low-dose vasopressin through a central venous catheter. An 84-year-old male was hospitalized for edema on both legs at Asan Medical Center, Seoul, Korea. On hospital day 8, the patient ..
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Original Article
The Effects of Methylene Blue on Hemodynamic Parameters and Cytokine Levels in Refractory Septic Shock
Byung-Kyu Park, Tae-Sun Shim, Chae-Man Lim, Sang-Do Lee, Woo-Sung Kim, Dong-Soon Kim, Won-Dong Kim, Younsuck Koh
Korean J Intern Med. 2005;20(2):123-128. Published online June 30, 2005
Background/AimsEndogenous nitric oxide (NO) induces the peripheral vasodilation via the activation of guanylate cyclase in patients with septic shock. The purpose of this study was to assess the acute effects of methylene blue (MB), which is an inhibitor of guanylate cyclase, ..
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