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Hemato-oncology
Geriatric risk model for older patients with diffuse large B-cell lymphoma (GERIAD): a prospective multicenter cohort study
Ho-Young Yhim, Yong Park, Jeong-A Kim, Ho-Jin Shin, Young Rok Do, Joon Ho Moon, Min Kyoung Kim, Won Sik Lee, Dae Sik Kim, Myung-Won Lee, Yoon Seok Choi, Seong Hyun Jeong, Kyoung Ha Kim, Jinhang Kim, Chang-Hoon Lee, Ga-Young Song, Deok-Hwan Yang, Jae-Yong Kwak
Korean J Intern Med. 2024;39(3):501-512. Published online January 30, 2024
Background/Aims: Optimal risk stratification based on simplified geriatric assessment to predict treatment-related toxicity and survival needs to be clarified in older patients with diffuse large B-cell lymphoma (DLBCL).
Methods: This multicenter prospective cohort study enrolled newly diagnosed pat..
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Infectious diseases
Incidence and risk factors for tenofovir-associated nephrotoxicity among human immunodeficiency virus-infected patients in Korea
Jeong Eun Lee, Shinwon Lee, Sang Heon Song, Ihm Soo Kwak, Sun Hee Lee
Korean J Intern Med. 2019;34(2):409-417. Published online October 12, 2017
Background/Aims: Little is known about tenofovir disoproxil fumarate (TDF)-induced nephrotoxicity in human immunodeficiency virus (HIV)-infected patients in Korea. The objective of this study was to evaluate the incidence and risk factors of TDF-associated nephrotoxicity among HIV-infected patients ..
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Nephrology
Update of aristolochic acid nephropathy in Korea
Tae Hyun Ban, Ji-Won Min, Changhwan Seo, Da Rae Kim, Yu Ho Lee, Byung Ha Chung, Kyung-Hwan Jeong, Jae Wook Lee, Beom Seok Kim, Sang-Ho Lee, Bum Soon Choi, Jin Suk Han, Chul Woo Yang
Korean J Intern Med. 2018;33(5):961-969. Published online March 20, 2018
Background/Aims: The true incidence of aristolochic acid nephropathy (AAN) is thought to be underestimated because numerous ingredients known or suspected to contain aristolochic acid (AA) are used in traditional medicine in Korea.
Methods: We collected data on cases of AAN since 1996 via a databas..
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Cardiology
Pathophysiology and preventive strategies of anthracycline-induced cardiotoxicity
Woo-Baek Chung, Ho-Joong Youn
Korean J Intern Med. 2016;31(4):625-633. Published online July 1, 2016
Cardiotoxicity is a well-known complication following treatment with anthracyclines. However, they are still widely used in chemotherapy for breast cancer, lymphoma, leukemia, and sarcoma, among others. Patient clinical characteristics, such as age, sex, comorbidities, anthracycline dose and infusio..
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The diagnostic utility of chest computed tomography scoring for the assessment of amiodarone-induced pulmonary toxicity
In Sook Kang, Kyung Jin Kim, Yookyung Kim, Seong-Hoon Park
Korean J Intern Med. 2014;29(6):746-753. Published online October 31, 2014
Background/Aims: Amiodarone is one of the most widely used antiarrhythmic agents; however, amiodarone-induced pulmonary toxicity (APT) can be irreversible and sometimes fatal. The aim of this study was to evaluate the feasibility of chest computed tomography (CT) as a diagnostic tool for APT and to ..
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Penicillin G-induced hemorrhagic cystitis: a case and review of the literature
Min-Kyung Kim, Chang Kyung Kang, Min Jae Kim, Kang Il Jun, Young-Kyun Lee, Seong Jin Jeong, Kyoung-Ho Song
Korean J Intern Med. 2013;28(6):743-745. Published online October 29, 2013
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Endocrinology-metabolism
Low glibenclamide concentrations affect endoplasmic reticulum stress in INS-1 cells under glucotoxic or glucolipotoxic conditions
Min Jeong Kwon, Hye Suk Chung, Chang Shin Yoon, Eun Ju Lee, Tae Kyun Kim, Soon Hee Lee, Kyung Soo Ko, Byoung Doo Rhee, Mi Kyung Kim, Jeong Hyun Park
Korean J Intern Med. 2013;28(3):339-346. Published online May 1, 2013
Background/Aimsβ-Cell apoptosis caused by increased endoplasmic reticulum (ER) stress is an important pathogenic component of type 2 diabetes mellitus. In theory, sulfonylureas, used for the treatment of diabetes, can contribute to ER stress. We assessed changes in ER stress ..
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A Comparison of Active Surveillance Programs Including a Spontaneous Reporting Model for Phamacovigilance of Adverse Drug Events in a Hospital
Il Seon Yun, Myung Jin Koo, Eun Hye Park, Sung-Eun Kim, Jae-Hyun Lee, Jung-Won Park, Chein-Soo Hong
Korean J Intern Med. 2012;27(4):443-450. Published online November 27, 2012
Background/AimsSpontaneous reporting systems have several weak points, such as low reporting rates and insufficient clinical information. Active surveillance programs, such as ward rounds and a clinical data repository (CDR), may supplement the weak points of such systems. We ..
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Established and Newly Proposed Mechanisms of Chronic Cyclosporine Nephropathy
Hye Eun Yoon, Chul Woo Yang
Korean J Intern Med. 2009;24(2):81-92. Published online June 8, 2009
Cyclosporine (CsA) has improved patient and graft survival rates following solid-organ transplantation and has shown significant clinical benefits in the management of autoimmune diseases. However, the clinical use of CsA is often limited by acute or chronic nephropathy, which remains a major pro..
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A Case of Green Urine after Ingestion of Herbicides
Yun-Suk Shim, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Soo-Hyun Kim, Sae-Yong Hong
Korean J Intern Med. 2008;23(1):42-44. Published online March 20, 2008
The development of discolored urine may have many possible causes. Here we present the case of a 76-year-old woman who was admitted after ingesting the inorganic herbicides, mefenacet and imazosulfuron. Her urine color changed to green almost immediately. Since the patient had no specific medicat..
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