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Rheumatology / Original Article
Predictors of renal relapse in Koreans with lupus nephritis after achieving complete response: a 35-years of experience at a single center
Howook Jeon, Jennifer Lee, Su-Jin Moon, Seung-Ki Kwok, Ji Hyeon Ju, Wan-Uk Kim, Sung-Hwan Park
Korean J Intern Med. 2024;39(2):347-359. Published online January 22, 2024
Background/Aims: Renal relapse has known to be a poor prognostic factor in patients with lupus nephritis (LN), but there were few studies that identified the risk factors of renal relapse in real world. We conducted this study based on 35-years of experience at a single center to find out predictors..
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Rheumatology / Original Article
Effect of belimumab in patients with systemic lupus erythematosus treated with low dose or no corticosteroids
Yeo-Jin Lee, Soo Min Ahn, Seokchan Hong, Ji-Seon Oh, Chang-Keun Lee, Bin Yoo, Yong-Gil Kim
Korean J Intern Med. 2024;39(2):338-346. Published online November 30, 2023
Background/Aims: Systemic lupus erythematosus (SLE) responder index (SRI)-4 response has been achieved with belimumab treatment in patients with moderate disease activity in cornerstone clinical trials and following studies. However, most studies involved patients treated with a mean prednisolone-eq..
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Rheumatology / Original Article
Long-term renal outcomes of patients with non-proliferative lupus nephritis
Eun-Song Kang, Soo Min Ahn, Ji Seon Oh, Yong-Gil Kim, Chang-Keun Lee, Bin Yoo, Seokchan Hong
Korean J Intern Med. 2023;38(5):769-776. Published online August 7, 2023
Background/Aims: Although non-proliferative lupus nephritis (LN) (class I, II or V) has been considered as a less severe type of LN, data on long-term renal prognosis are limited. We investigated the long-term outcomes and prognostic factors in non-proliferative LN.
Methods: We retrospectively revi..
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Rheumatology / Original Article
Epidemiology and risk factors associated with avascular necrosis in patients with autoimmune diseases: a nationwide study
Hsin-Lin Tsai, Jei-Wen Chang, Jen-Her Lu, Chin-Su Liu
Korean J Intern Med. 2022;37(4):864-876. Published online March 3, 2022
Background/Aims: Avascular necrosis (AVN) is a clinical condition characterized by the death of bone components due to interruption in the blood supply. This study aimed to investigate the epidemiology and determine the risk factors for AVN in patients with autoimmune diseases.
Methods: We conducte..
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Rheumatology / Original Article
The relationship between anti-C-reactive protein and disease activity in patients with systemic lupus erythematosus
Chang-Nam Son, Tae-Han Lee, Ji-Hye Bang, Hye-Jin Jeong, Jin-Nyeong Chae, Won-Mok Lee, Ji-Min Kim, Sang-Hyon Kim
Korean J Intern Med. 2018;33(4):823-828. Published online March 31, 2017
Background/Aims: Anti-C-reactive protein (CRP) antibody has been introduced as a potential biologic marker in Systemic lupus erythematosus (SLE). The aim of study is to evaluate the level of anti-CRP antibody in patients with SLE.
Methods: This study investigated the relationship between levels of..
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Rheumatology / Review
New insights into the role of renal resident cells in the pathogenesis of lupus nephritis
Seung-Ki Kwok, George C. Tsokos
Korean J Intern Med. 2018;33(2):284-289. Published online January 12, 2018
Systemic lupus erythematosus (SLE), an autoimmune disease of unknown etiology, is characterized by the production of autoantibodies and end-organ damage. Lupus nephritis affects up to 70% of patients with SLE and is the most critical predictor of morbidity and mortality. The immunopathogenesis of SL..
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Rheumatology / Original Article
Clinical characteristics of male and female Korean patients with systemic lupus erythematosus: a comparative study
Jiwon Hwang, Jaejoon Lee, Joong Kyoung Ahn, Eun-Jung Park, Hoon-Suk Cha, Eun-Mi Koh
Korean J Intern Med. 2015;30(2):242-249. Published online February 27, 2015
Background/Aims: To compare the clinical characteristics and outcomes of systemic lupus erythematosus between male and female Korean patients.
Methods: A retrospective analysis was performed at a single tertiary hospital from August 1994 to May 2010. Male patients were matched with two to three fem..
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Case Report
An Antinuclear Antibody-Negative Patient With Lupus Nephritis
Hyoun-Ah Kim, Jae-Wook Chung, Han-Jung Park, Dai-Yeol Joe, Hyun-Ee Yim, Hae-Sim Park, Chang-Hee Suh
Korean J Intern Med. 2009;24(1):76-79. Published online March 6, 2009
Systemic lupus erythematosus (SLE) is a typical autoimmune disease that's characterized by various autoantibodies to nuclear and cytoplasmic antigens. The presence of antinuclear antibodies (ANA) in serum is generally considered a decisive diagnostic sign of SLE. However, a small subset of SLE pa..
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Original Article
Comparison of the Clinical Manifestations, Brain MRI and Prognosis between NeuroBehçet's Disease and Neuropsychiatric Lupus
Byung-Sik Cho, Hyun-Sook Kim, Su-Jin Oh, Hyeok-Jae Ko, Chong-Hyun Yoon, So-Lyung Jung, Do-June Min, Wan-Uk Kim
Korean J Intern Med. 2007;22(2):77-86. Published online June 30, 2007
BackgroundNeuropsychiatric systemic lupus erythematosus (NPSLE) shows some similarities to neuroBehçet's disease (NBD) in that both conditions have some analogous clinical features and they are both pathologically associated cerebral vasculopathy. This study compared the cli..
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