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Allergy
N-acetylcysteine decreases airway inflammation and responsiveness in asthma by modulating claudin 18 expression
Pureun-Haneul Lee, Jisu Hong, An-Soo Jang
Korean J Intern Med. 2020;35(5):1229-1237. Published online February 28, 2020
Background/Aims: N-acetylcysteine (NAC) affects signaling pathways involved in apoptosis, angiogenesis, cell growth and arrest, redox-regulated gene expression, and the inflammatory response. However, it is not known how the signal mechanism for tight junctional protein claudin (CLDN) 18 is regulate..
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Infectious diseases
Application of therapeutic plasma exchange in patients having severe fever with thrombocytopenia syndrome
Jeong Rae Yoo, Sun Hyung Kim, Young Ree Kim, Keun Hwa Lee, Won Sup Oh, Sang Taek Heo
Korean J Intern Med. 2019;34(4):902-909. Published online November 10, 2017
Background/Aims: Severe fever with thrombocytopenia syndrome (SFTS) is a viral hemorrhagic fever with a high fatality rate. However, effective treatments for SFTS cases not responded to supportive therapy have not been established. Herein, we introduced the therapeutic plasma exchange (TPE) in SFTS ..
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Hemato-oncology
Clinical features and treatment outcomes of blastic plasmacytoid dendritic cell neoplasm: a single-center experience in Korea
Hae Su Kim, Hee-Jin Kim, Sun-Hee Kim, Joon Young Choi, Young Hyeh Ko, Won Seog Kim, Chul Won Jung, Seok Jin Kim
Korean J Intern Med. 2017;32(5):890-899. Published online August 18, 2017
Background/Aims: Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare hematologic malignancy that typically presents in the form of skin manifestations with or without lymph node and bone marrow involvement. Given its rarity and recent recognition as a distinct pathological entity, no stan..
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Nephrology
Effects of pretransplant plasmapheresis and rituximab on recurrence of focal segmental glomerulosclerosis in adult renal transplant recipients
Hoon Suk Park, Yuah Hong, In O Sun, Byung Ha Chung, Hyung Wook Kim, Bum Soon Choi, Cheol Whee Park, Dong Chan Jin, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2014;29(4):482-488. Published online June 27, 2014
Background/Aims: Recurrent focal segmental glomerulosclerosis (FSGS) following renal transplantation is relatively common. However, the risk factors and optimal pretransplant treatment preventing recurrence of FSGS remain controversial.
Methods: We retrospectively reviewed 27 adult renal transplan..
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Primary Pulmonary Plasmacytoma Presenting as Multiple Lung Nodules
Sang-Heon Kim, Tae Hyung Kim, Jang Won Sohn, Ho Joo Yoon, Dong Ho Shin, In Soon Kim, Sung Soo Park
Korean J Intern Med. 2012;27(1):111-113. Published online February 28, 2012
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Predictive Value of Post-Transplant Bone Marrow Plasma Cell Percent in Multiple Myeloma Patients Undergone Autologous Transplantation
In Hye Hwang, Joo Seop Chung, Ho Jin Shin, Young Jin Choi, Moo Kon Song, Young Mi Seol, Goon Jae Cho, Bo Gwang Choi, Mun Ki Choi, Bo Kyung Choi, Kang Hee Ahn, Kyung Hwa Shin, Hee Sun Lee, Hyung Seok Nam, Jong Min Hwang
Korean J Intern Med. 2011;26(1):76-81. Published online March 2, 2011
Background/AimsAutologous stem cell transplantation (ASCT) has become the treatment of choice for patients with multiple myeloma (MM). Studies have shown that maintenance treatment with interferon-alpha is associated with improved survival rates following ASCT. However, despit..
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High-dose Immunoglobulin Infusion for Thrombotic Thrombocytopenic Purpura Refractory to Plasma Exchange and Steroid Therapy
Seh Jong Park, Seok Jin Kim, Hee Yun Seo, Moon Ju Jang, Doyeun Oh, Byung Soo Kim, Jun Suk Kim
Korean J Intern Med. 2008;23(3):161-164. Published online September 20, 2008
The outcomes of the treatment of thrombotic thrombocytopenic purpura (TTP) have been shown to be improved by the administration of plasma exchange. However, treatment options are currently limited for cases refractory to plasma exchange. The autoantibodies that block the activity of ADAMTS13 have..
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A Case of Primary Plasmacytoma of Lymph Nodes
Young Hyo Lim, Su Kyoung Park, Ho Suk Oh, Jung Hye Choi, Myung Ju Ahn, Young Yul Lee, In Soon Kim
Korean J Intern Med. 2005;20(2):183-186. Published online June 30, 2005
Extramedullary plasmacytoma may originate in any organ, either as a primary tumor or as a facet of systemic multiple myeloma. These solid lesions most commonly affect the upper respiratory tract, gastrointestinal and urogenital tract, skin, and lung. Primary plasmacytoma of the lymph node is a ra..
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A Case of Extramedullary Plasmacytoma Arising from the Posterior Mediastinum
Sung Yong Lee, Je Hyeong Kim, Jae Seung Shin, Chol Shin, Kwang Ho In, Kyung Ho Kang, Se Hwa Yoo
Korean J Intern Med. 2005;20(2):173-176. Published online June 30, 2005
Plasmacytomas are a localized proliferation of plasma cells in the bone marrow, and are less frequently seen in extraosseous organs or tissues. Extramedullary plasmacytoma is a rare malignant neoplasm, and is especially uncommon when it arises from the mediastinum. Here, we report on a case of po..
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A Case of Pulmonary Inflammatory Pseudotumor: Recurrence Appearing as Several Consolidative Lesions after Complete Resection
Hong-Lyeol Lee, Lucia Kim, Kyung-Hee Lee, Kwang-Ho Kim, Cheol-Woo Kim
Korean J Intern Med. 2005;20(2):168-172. Published online June 30, 2005
Inflammatory pseudotumor (plasma cell granuloma) of the lung is an uncommon nonneoplastic tumor of unknown origin. This tumor typically manifests as a solitary, peripheral, and sharply circumscribed mass. Multiple lesions are seen in about 5% of cases. Resection is recommended for both diagnosis ..
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