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Hemato-oncology
Risk factors for neutropenic fever in non-Hodgkin’s lymphoma patients with primary granulocyte colony-stimulating factor prophylaxis
Yu Ri Kim, Soo-Jeong Kim, Yong Park, Sung Yong Oh, Hwan-Jung Yun, Yeung-Chul Mun, Jin Seok Kim; the Korean Society of Hematology Lymphoma Working Party
Korean J Intern Med. 2021;36(5):1181-1189. Published online July 16, 2021
Background/Aims: Febrile neutropenia (FN) interferes with the proper chemotherapy dose density or intensity in non-Hodgkin’s lymphoma (NHL) patients. Chemotherapy with cyclophosphamide, doxorubicin, vincristine, and prednisone (CHOP) ± rituximab has an intermediate FN risk. Prophylactic granulocy..
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Infectious diseases
Cancer patients with neutropenic septic shock: etiology and antimicrobial resistance
Sung Min Jung, Youn Jung Kim, Seung Mok Ryoo, Chang Hwan Sohn, Dong Woo Seo, Kyoung Soo Lim, Won Young Kim
Korean J Intern Med. 2020;35(4):979-987. Published online October 28, 2019
Background/Aims: Among patients with febrile neutropenia that developed after chemotherapy, high-risk patients, such as those having clinical instability or Multinational Association of Supportive Care in Cancer score of < 21, require hospitalization for intravenous empiric antibiotic therapy. Mono..
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Recurrent neutropenia induced by rifabutin in a renal transplant recipient
Ji Yeun Chang, Eun Gyo Jeong, Ji Hyun Yu, Byung Ha Chung, Chul Woo Yang
Korean J Intern Med. 2014;29(4):532-534. Published online June 27, 2014
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Sudden Atelectasis and Respiratory Failure in a Neutropenic Patient: Atypical Presentation of Pseudomembranous Necrotizing Bronchial Aspergillosis
Ji Yun Noh, Seok Jin Kim, Eun Hae Kang, Bo Kyoung Seo, Kyoung Ho Rho, Yang-Seok Chae, Byung Soo Kim
Korean J Intern Med. 2012;27(4):463-466. Published online November 27, 2012
Pseudomembranous necrotizing bronchial aspergillosis (PNBA) is a rare form of invasive aspergillosis with a very poor prognosis. The symptoms are non-specific, and the necrotizing plugs cause airway obstruction. Atelectasis and respiratory failure can be the initial manifestations. Recently, we t..
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Evidence-Based Guidelines for Empirical Therapy of Neutropenic Fever in Korea
Dong-Gun Lee, Sung-Han Kim, Soo Young Kim, Chung-Jong Kim, Wan Beom Park, Young Goo Song, Jung-Hyun Choi
Korean J Intern Med. 2011;26(2):220-252. Published online June 1, 2011
Neutrophils play an important role in immunological function. Neutropenic patients are vulnerable to infection, and except fever is present, inflammatory reactions are scarce in many cases. Additionally, because infections can worsen rapidly, early evaluation and treatments are especially importa..
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Intravenous Itraconazole vs. Amphotericin B Deoxycholate for Empirical Antifungal Therapy in Patients with Persistent Neutropenic Fever
Sun Hee Park, Su-Mi Choi, Dong-Gun Lee, Jung-Hyun Choi, Jin-Hong Yoo, Woo-Sung Min, Wan-Shik Shin
Korean J Intern Med. 2006;21(3):165-172. Published online September 30, 2006
BackgroundAmphotericin B dexoycholate is currently the standard empirical antifungal therapy for neutropenic patients with hematologic malignancies and who also have persistent fever that does not respond to antibacterial therapy. The antifungal triazoles offer a potentially s..
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