Hemato-oncology
Targeting the CXCL12/CXCR4 axis in acute myeloid leukemia: from bench to bedside
Byung-Sik Cho, Hee-Je Kim, Marina Konopleva
Korean J Intern Med. 2017;32(2):248-257. Published online February 21, 2017
The interactions between the cancerous cells of acute myeloid leukemia (AML) and the bone marrow (BM) microenvironment have been postulated to be important for resistance to chemotherapy and disease relapse in AML. The chemokine receptor CXC chemokine receptor 4 (CXCR4) and its ligand, CXC motif li..
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