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Rheumatology
Effectiveness of Korean Red Ginseng on fatigue in patients with rheumatic diseases: a randomized, double-blind, placebo-controlled study
Soo-Kyung Cho, Yeo-Jin Song, Jung-Yong Han, Hye Won Kim, Eunwoo Nam, Yoon-Kyoung Sung
Korean J Intern Med. 2024;39(4):680-690. Published online April 5, 2024
Background: To evaluate the effectiveness of Korean Red Ginseng (KRG) in managing fatigue in Korean patients with rheumatic diseases
Methods: Patients were randomly assigned to KRG (2 g/day, n = 60) or placebo (n = 60) groups for 12 weeks of blind phase and then open-label KRG from weeks 12 to 24 (..
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Geriatrics
Factors associated with anticholinergic burden among older patients in long-term care hospitals in Korea
Jung-Yeon Choi, Hongsoo Kim, Young-il Jung, Seungyeon Chun, Sooyoung Yoo, Jae-Young Lim, Jin Young Ko, Kayoung Park, Kwang-il Kim
Korean J Intern Med. 2022;37(2):468-477. Published online February 18, 2022
Background/Aims: Drugs with anticholinergic properties (DAPs) are associated with adverse health outcomes in older patients. The objective of this study was to evaluate the factors that determine the prescribing of more DAPs in long-term care hospitals (LTCHs) in Korea. In addition, the current patt..
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Rheumatology
Reliability and validity of the Korean version of the University of California–Los Angeles Scleroderma Clinical Trial Consortium Gastrointestinal Tract instrument in patients with systemic sclerosis
Tae Hee Lee, Joon Seong Lee, Suyeon Park, Kyung-Ann Lee, Hyun-Sook Kim
Korean J Intern Med. 2021;36(6):1504-1514. Published online February 10, 2021
Background/Aims: Systemic sclerosis (SSc) is associated with a wide range of gastrointestinal (GI) changes. The University of California–Los Angeles Scleroderma Clinical Trial Consortium Gastrointestinal Tract (UCLA SCTC GIT 2.0) instrument is a self-administered GI assessment instrument for patie..
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Hemato-oncology
Treatment outcome and prognostic factors of Korean patients with chronic lymphocytic leukemia: a multicenter retrospective study
Yunsuk Choi, Jung-Hee Lee, Chul Won Jung, Jae-Cheol Jo, Jin Seok Kim, Inho Kim, Silvia Park, June-won Cheong, Sang-Hyuk Park, Sung-Yong Kim, Hong-Ghi Lee
Korean J Intern Med. 2021;36(1):194-204. Published online April 14, 2020
Background/Aims: Compared with Western countries, chronic lymphocytic leukemia (CLL) rarely occurs in Asia and has different clinical characteristics. Thus, we aimed to evaluate the clinical characteristics, treatment outcomes, and prognostic significance of Korean patients with CLL.
Methods: We re..
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Endocrinology-metabolism
Predictive costs in medical care for Koreans with metabolic syndrome from 2009 to 2013 based on the National Health Insurance claims dataset
Jeong Seon Yoo, Eun Yeong Choe, Yoo Mee Kim, Se Hwa Kim, Young Jun Won
Korean J Intern Med. 2020;35(4):936-945. Published online August 19, 2019
Background/Aims: Although metabolic syndrome has been associated with increasing medical costs worldwide, there have been no studies using a nationwide and longitudinal South Korean dataset. We investigated trends in subsidized medical costs among Korean adults with metabolic syndrome.
Methods: Thi..
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Site-specific cancer risk in patients with type 2 diabetes: a nationwide population-based cohort study in Korea
Suk Kyeong Kim, Ju-Young Jang, Dong-Lim Kim, Young A Rhyu, Suh Eun Lee, Seung-Hyun Ko, Kyungdo Han, Kee-Ho Song; On behalf of the Task Force Team for Diabetes Fact Sheet of the Korean Diabetes Association
Korean J Intern Med. 2020;35(3):641-651. Published online September 3, 2018
Background/Aims: We aimed to evaluate site-specific cancer risk in diabetic patients and to investigate causal and temporal relationships by analyzing organ-specific cancer risk according to the duration of diabetes.
Methods: Using a database provided by the Korean National Health Insurance Service..
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Rheumatology
Efficacy and safety of tocilizumab in Korean patients with active rheumatoid arthritis
Han Joo Baek, Mie Jin Lim, Won Park, Sung Hwan Park, Seung-Cheol Shim, Dae-Hyun Yoo, Hyun Ah Kim, Soo Kon Lee, Yun Jong Lee, Young Eun Park, Hoon-Suk Cha, Yeong-Wook Song
Korean J Intern Med. 2019;34(4):917-931. Published online January 17, 2018
Background/Aims: To investigate the efficacy and safety of tocilizumab (TCZ) humanized anti-interleukin-6 receptor monoclonal antibody, in Korean patients with active rheumatoid arthritis (RA) refractory to conventional disease modifying anti-rheumatic drugs (DMARDs) including methotrexate (MTX)
Me..
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Allergy
Korean version of the Cough Symptom Score: clinical utility and validity for chronic cough
Jae-Woo Kwon, Ji-Yong Moon, Sae-Hoon Kim, Woo-Jung Song, Min-Hye Kim, Min-Gyu Kang, Kyung-Hwan Lim, So-Hee Lee, Sang Min Lee, Jin Young Lee, Hyouk-Soo Kwon, Kyung-Mook Kim, Sang-Heon Kim, Sang-Hoon Kim, Jae-Won Jeong, Cheol-Woo Kim, Sang-Heon Cho, Byung-Jae Lee; Work Group for Chronic Cough, the Korean Academy of Asthma, Allergy and Clinical Immunology
Korean J Intern Med. 2017;32(5):910-915. Published online March 31, 2017
Background/Aims: The Cough Symptom Score (CSS) is a simple, useful tool for measuring cough severity. However, there is no standard Korean version of the CSS. We developed a Korean version of the CSS and evaluated its clinical utility and validity for assessing chronic cough severity.
Methods: The..
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Hemato-oncology
Assessment of bone marrow involvement in patients with lymphoma: report on a consensus meeting of the Korean Society of Hematology Lymphoma Working Party
Yong Park, Byung Bae Park, Ji Yun Jeong, Wook Youn Kim, Seongsoo Jang, Bong Kyung Shin, Dong Soon Lee, Jae Ho Han, Chan-Jeoung Park, Cheolwon Suh, Insun Kim, Hyun-Sook Chi
Korean J Intern Med. 2016;31(6):1030-1041. Published online November 1, 2016
In September 2011, the Korean Society of Hematology Lymphoma Working Party held a nationwide conference to establish a consensus for assessing bone marrow (BM) involvement in patients with lymphoma. At this conference, many clinicians, hematopathologists, and diagnostic hematologists discussed vario..
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Pulmonology
Smoking habits and nicotine dependence of North Korean male defectors
Sei Won Kim, Jong Min Lee, Woo Ho Ban, Chan Kwon Park, Hyoung Kyu Yoon, Sang Haak Lee
Korean J Intern Med. 2016;31(4):685-693. Published online March 8, 2016
Background/Aims: The smoking rates and patterns in the North Korean population are not well known. More than 20,000 North Korean defectors have settled in South Korea; thus, we can estimate the current North Korean smoking situation using this group.
Methods: All North Korean defectors spend their ..
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Hemato-oncology
Chronic lymphocytic leukemia: a clinical review including Korean cohorts
Young-Woo Jeon, Seok-Goo Cho
Korean J Intern Med. 2016;31(3):433-443. Published online April 5, 2016
Only 5th decade ago, chronic lymphocytic leukemia (CLL) was only recognized as disease group of presenting features like peripheral lymphocytosis, organomegaly including of splenomegaly. As understanding of disease biology and molecular diagnostic tools are getting improved gradually, characterizati..
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Assessment of the Efficacy of Reducing Peginterferon Alfa-2a and Ribavirin Dose on Virologic Response in Koreans with Chronic Hepatitis C
Jung Hyun Kwon, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Kwan Soo Byun, Seung Woon Paik, Young Suk Lim, Han Chu Lee, Kwang Hyub Han, Kwan Sik Lee
Korean J Intern Med. 2009;24(3):203-211. Published online August 26, 2009
Background/AimsThe virologic response of Koreans to combination therapy for chronic hepatitis C is similar to westerns; however, dose modification occurs more frequently in Koreans. We evaluated the rates of peginterferon α-2a and ribavirin dose modifications and their effect o..
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