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Cardiology
Efficacy of single-dose evolocumab injection in early-phase acute myocardial infarction: a retrospective single-center study
Yongcheol Kim, Ji Woong Roh, Oh-Hyun Lee, Seok-Jae Heo, Eui Im, Deok-Kyu Cho, Byeong-Keuk Kim
Korean J Intern Med. 2024;39(5):793-800. Published online June 24, 2024
Background/Aims: Achieving rapid reduction of low-density lipoprotein cholesterol (LDL-C) levels below 55 mg/dL in patients with acute myocardial infarction (AMI) can be challenging with statins alone. This single-center, retrospective study aimed to assess the impact of single-dose injection of evo..
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Time to presentation and mortality outcomes among patients with diabetes and acute myocardial infarction
Min-A Shin, Seok Oh, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong
Korean J Intern Med. 2024;39(1):110-122. Published online December 11, 2023
Background/Aims: Due to limited real-world evidence on the association between time to presentation (T2P) and outcomes following acute myocardial infarction and diabetes (AMI-DM), we investigated the characteristics of patients with AMI-DM and their outcomes based on their T2P.
Methods: 4,455 patie..
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Treatment delay and outcomes of ST-segment elevation myocardial infarction treated by primary percutaneous coronary intervention during the COVID-19 era in South Korea
Seok Oh, Myung Ho Jeong, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn
Korean J Intern Med. 2022;37(4):786-799. Published online June 28, 2022
Background/Aims: Little is known about the clinical characteristics and treatment outcomes of ST-segment elevation myocardial infarction (STEMI) in Korea during the coronavirus disease 2019 (COVID-19) era. We aimed to evaluate the clinical characteristics and treatment outcomes of patients with STEM..
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Predictors of recurrent acute myocardial infarction despite successful percutaneous coronary intervention
Sang Hun Lee, Myung Ho Jeong, Joon Ho Ahn, Dae Young Hyun, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Youngkeun Ahn, Jin Yong Hwang, Weon Kim, Jong Seon Park, Chang-Hwan Yoon, Seung Ho Hur, Sang Rok Lee, Kwang Soo Cha; on behalf of the KAMIR (Korea Acute Myocardial Infarction Registry)-NIH Investigators
Korean J Intern Med. 2022;37(4):777-785. Published online June 28, 2022
Background/Aims: Recurrent acute myocardial infarction (AMI) is an adverse cardiac event in patients with a first AMI. The predictors of recurrent AMI after the first AMI in patients who underwent successful percutaneous coronary intervention (PCI) have not been elucidated.
Methods: We analyzed th..
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Long-term outcomes in ST-elevation myocardial infarction patients treated according to hospital visit time
Seok Oh, Dae Young Hyun, Kyung Hoon Cho, Ju Han Kim, Myung Ho Jeong
Korean J Intern Med. 2022;37(3):605-617. Published online November 16, 2021
Background/Aims: Rapid percutaneous coronary intervention (PCI) is the cornerstone of treatment for ST-elevation myocardial infarction (STEMI). However, there have been conflicting results regarding the differences in clinical outcomes between on-hours and off-hours presentation in STEMI patients. W..
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Off-hour presentation and outcomes for percutaneous coronary intervention in acute myocardial infarction with Killip III–IV
Seok Oh, Ju Han Kim, Kyung Hoon Cho, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Myung Ho Jeong
Korean J Intern Med. 2022;37(3):591-604. Published online April 28, 2022
Background/Aims: Acute myocardial infarction (AMI) is conventionally recognized as an urgent medical condition requiring timely and effective reperfusion therapy. However, the results of studies on the clinical outcomes in AMI according to hospital visit timings are inconclusive. To explore the differ..
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The current status and outcomes of in-hospital P2Y12 receptor inhibitor switching in Korean patients with acute myocardial infarction
Keun-Ho Park, Myung Ho Jeong, Hyun Kuk Kim, Young-Jae Ki, Sung Soo Kim, Youngkeun Ahn, Hyun Yi Kook, Hyo-Soo Kim, Hyeon Cheol Gwon, Ki Bae Seung, Seung Woon Rha, Shung Chull Chae, Chong Jin Kim, Kwang Soo Cha, Jong Seon Park, Jung Han Yoon, Jei Keon Chae, Seung Jae Joo, Dong-Joo Choi, Seung Ho Hur, In Whan Seong, Myeong Chan Cho, Doo Il Kim, Seok Kyu Oh, Tae Hoon Ahn, Jin Yong Hwang; on behalf of the KAMIR-NIH registry investigators
Korean J Intern Med. 2022;37(2):350-365. Published online January 12, 2022
Background/Aims: While switching strategies of P2Y12 receptor inhibitors (RIs) have sometimes been used in acute myocardial infarction (AMI) patients, the current status of in-hospital P2Y12RI switching remains unknown.
Methods: Overall, 8,476 AMI patients who underwent successful revascularization..
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Sex differences in long-term clinical outcomes of acute myocardial infarction according to the presence of diabetes mellitus
Yu Ri Kim, Myung Ho Jeong, Youngkeun Ahn, Ju Han Kim, Young Joon Hong, Min Chul Kim, Kyung Hoon Cho, Xiong Yi Han; other KAMIR-NIH Registry Investigators
Korean J Intern Med. 2021;36(Suppl 1):S99-S113. Published online January 12, 2021
Background/Aims: This study compared long-term clinical outcomes between male and female acute myocardial infarction (AMI) patients with and without diabetes mellitus (DM).
Methods: From November 2011 to December 2015, 13,104 patients with AMI were enrolled in the Korea Acute Myocardial Infarction ..
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Long-term efficacy of vasodilating β-blocker in patients with acute myocardial infarction: nationwide multicenter prospective registry
Jaehoon Chung, Jung-Kyu Han, Han-Mo Yang, Kyung-Woo Park, Hyun-Jae Kang, Bon-Kwon Koo, Myung Ho Jeong, Hyo-Soo Kim; on behalf of investigators for Korea Acute Myocardial Infarction Registry (KAMIR)
Korean J Intern Med. 2021;36(Suppl 1):S62-S71. Published online July 3, 2020
Background/Aims: Long-term benefit of vasodilating β-blockers is unknown. This study aimed to investigate the long-term benefit of vasodilating β-blockers over conventional β-blockers in patients with acute myocardial infarction (AMI).
Methods: Using nationwide prospective multicenter Korean Acute ..
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Feasibility of primary percutaneous coronary intervention via the distal radial approach in patients with ST-elevation myocardial infarction
Yongcheol Kim, Jun-Won Lee, Sang Yeub Lee, Jang-Whan Bae, Sang Jun Lee, Myung Ho Jeong, Seung-Hwan Lee, Youngkeun Ahn
Korean J Intern Med. 2021;36(Suppl 1):S53-S61. Published online March 3, 2020
Background/Aims: Recently, distal radial approach (DRA), called as snuffbox approach, has gained the interest of interventional cardiologists, but there is a lack of data about the feasibility of DRA as an alternative route for primary percutaneous coronary intervention (PCI).
Methods: A total of 1..
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Clinical characteristics of spontaneous coronary artery dissection in young female patients with acute myocardial infarction in Korea
Yongcheol Kim, Xiongyi Han, Youngkeun Ahn, Min Chul Kim, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Myung Ho Jeong
Korean J Intern Med. 2021;36(1):106-113. Published online July 18, 2019
Background/Aims: We aimed to evaluate the prevalence, characteristics, and clinical outcomes of spontaneous coronary artery dissection (SCAD) in young female patients with acute myocardial infarction (AMI).
Methods: We identified 8,250 patients diagnosed with AMI who underwent coronary angiogram fr..
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Infectious diseases
Mediation effect of herpes zoster derived by statin use on cardiovascular disease risk
Sung-Han Kim, Sung-Cheol Yun, Young-Ho Khang, Min-Chul Kim, Sun Uck Kwon, Gyung-Min Park, Young-Rak Cho, Kwang Min Lee, Moo Hyun Kim
Korean J Intern Med. 2020;35(5):1220-1228. Published online June 19, 2020
Background/Aims: Although statins are widely used to reduce the risk of cardiovascular disease (CVD) including stroke and myocardial infarction (MI), it is reported that statin use increases the incidence of herpes zoster (HZ) that is associated with increased risk of CVD. So, we evaluated the media..
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Cardiology
Pre-hospital delay and emergency medical services in acute myocardial infarction
Seung Hun Lee, Hyun Kuk Kim, Myung Ho Jeong, Joo Myung Lee, Hyeon-Cheol Gwon, Shung Chull Chae, In-Whan Seong, Jong-Seon Park, Jei Keon Chae, Seung-Ho Hur, Kwang Soo Cha, Hyo-Soo Kim, Ki-Bae Seung, Seung-Woon Rha, Tae Hoon Ahn, Chong-Jin Kim, Jin-Yong Hwang, Dong-Ju Choi, Junghan Yoon, Seung-Jae Joo, Kyung-Kuk Hwang, Doo-Il Kim, Seok Kyu Oh; for the KAMIR Investigators
Korean J Intern Med. 2020;35(1):119-132. Published online November 28, 2019
Background/Aims: Minimising total ischemic time (TIT) is important for improving clinical outcomes in patients with ST-segment elevation myocardial infarction who have undergone percutaneous coronary intervention (PCI). TIT has not shown a significant improvement due to persistent pre-hospital delay..
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D-dimer/troponin ratio in the differential diagnosis of acute pulmonary embolism from non-ST
elevation myocardial infarction
Jong Yoon Kim, Kye Hun Kim, Jae Yeong Cho, Doo Sun Sim, Hyun Ju Yoon, Nam Sik Yoon, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park
Korean J Intern Med. 2019;34(6):1263-1271. Published online January 28, 2019
Background/Aims: The aim of this study was to investigate useful cardiac biomarkers in the differential diagnosis of acute pulmonary embolism (APE) with troponin elevation from acute non-ST elevation myocardial infarction (NSTEMI). Methods: A total of 771 consecutive NSTEMI patients with D-dimer mea..
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Clinical characteristics and outcomes in acute myocardial infarction patients with versus without any cardiovascular risk factors
Ah-Ra Choi, Myung Ho Jeong, Young Joon Hong, Seok-Joon Sohn, Hyun Yi Kook, Doo Sun Sim, Young Keun Ahn, Ki Hong Lee, Jae Yeong Cho, Young Jo Kim, Myeong Chan Cho, Chong Jin Kim; other Korea Acute Myocardial Infarction Registry Investigators
Korean J Intern Med. 2019;34(5):1040-1049. Published online September 1, 2018
Background/Aims: Although cardiovascular (CV) risk factors are well established, some patients experience acute myocardial infarction (AMI) even without any risk factors.
Methods: We analyzed total 11,390 patients (63.6 ± 12.6 years old, 8,401 males) with AMI enrolled in Korea Acute Myocardial In..
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A score for decision making during percutaneous coronary intervention in acute myocardial infarction patients with multivessel disease
Hae Chang Jeong, Joon Ho Ahn, Min Chul Kim, Doo Sun Sim, Keun Ho Park, Young Joon Hong, Ju Han Kim, Myung Ho Jeong, Ki-Bae Seung, Kiyuk Chang, Youngkeun Ahn
Korean J Intern Med. 2019;34(2):324-334. Published online March 20, 2018
Background/Aims: The optimal percutaneous coronary intervention (PCI) strategy in patients with acute myocardial infarction (AMI) with multivessel disease (MVD) is uncertain. This study was designed to develop a novel and simple tool for assessing an individualized and optimized PCI strategy in AMI ..
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Current status of acute myocardial infarction in Korea
Yongcheol Kim, Youngkeun Ahn, Myeong Chan Cho, Chong Jin Kim, Young Jo Kim, Myung Ho Jeong
Korean J Intern Med. 2019;34(1):1-10. Published online December 28, 2018
Coronary artery disease, especially acute myocardial infarction (AMI), is a leading cause of death in the Asia-Pacific region. The Korea Acute Myocardial Infarction Registry (KAMIR) is the first nationwide, prospective, multicenter registry of Korean patients with AMI. Since the KAMIR first began in..
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Prognostic significance of non-chest pain symptoms in patients with non-ST-segment elevation myocardial infarction
Inna Kim, Min Chul Kim, Keun Ho Park, Doo Sun Sim, Young Joon Hong, Ju Han Kim, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park, Myeong Chan Cho, Jong Jin Kim, Young Jo Kim, Youngkeun Ahn; the Korea Acute Myocardial Infarction Registry Investigators
Korean J Intern Med. 2018;33(6):1111-1118. Published online November 10, 2017
Background/Aims: Chest pain is an essential symptom in the diagnosis of acute coronary syndrome (ACS). One-third of patients with ACS present atypically, which can influence their receiving timely lifesaving therapy.
Methods: A total of 617 NSTEMI patients from the Korea Acute MI Registry (KAMIR) ..
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Transradial versus transfemoral intervention in ST-segment elevation myocardial infarction patients in Korean population
Hu Li, Seung-Woon Rha, Byoung Geol Choi, Min Suk Shim, Se Yeon Choi, Cheol Ung Choi, Eung Ju Kim, Dong Joo Oh, Byung Ryul Cho, Moo Hyun Kim, Doo-Il Kim, Myung-Ho Jeong, Sang Yong Yoo, Sang-Sik Jeong, Byung Ok Kim, Min Su Hyun, Young-Jin Youn, Junghan Yoon
Korean J Intern Med. 2018;33(4):716-726. Published online July 7, 2017
Background/Aims: Transradial intervention (TRI) is becoming the preferred method over transfemoral intervention (TFI) because TRI is associated with lower incidence of major bleeding and vascular complications. However, there has been limited published data regarding the clinical outcomes of TRI ver..
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Prognostic value of total triiodothyronine and free thyroxine levels for the heart failure in patients with acute myocardial infarction
Min Gyu Kang, Jong Ryeal Hahm, Kye-Hwan Kim, Hyun-Woong Park, Jin-Sin Koh, Seok-Jae Hwang, Jin-Yong Hwang, Jong Hwa Ahn, Yongwhi Park, Young-Hoon Jeong, Jeong Rang Park, Choong Hwan Kwak
Korean J Intern Med. 2018;33(3):512-521. Published online January 11, 2017
Background/Aims: Although a low triiodothyronine (T3) state is closely associated with heart failure (HF), it is uncertain whether total T3 levels on admission is correlated with the clinical outcomes of acute myocardial infarction (AMI). The aim of this study is to investigate the prognostic value..
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