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Endocrinology-metabolism
Benefits of lumican on human bone health: clinical evidence using bone marrow aspirates
Yun Sun Lee, So Jeong Park, Jin Young Lee, Eunah Choi, Beom-Jun Kim
Korean J Intern Med. 2022;37(4):821-829. Published online April 26, 2022
Background/Aims: Lumican, a small leucine-rich proteoglycan, has shown osteoprotective effects by synchronously stimulating bone formation and suppressing bone resorption. To clarify the role of lumican in human bone metabolism, the association between lumican concentrations and osteoporosis-related..
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Pulmonology
Acute exacerbation of COPD increases the risk of hip fractures: a nested case-control study from the Korea National Health Insurance Service
Kang-Mo Gu, Sang-Won Yoon, Sun-Young Jung, Moon Seong Baek, Won Young Kim, Jae-Woo Jung, Jae-Chol Choi, Jong-Wook Shin, Jae-Yeol Kim, Byoung-Whui Choi, In-Won Park
Korean J Intern Med. 2022;37(3):631-638. Published online February 8, 2022
Background/Aims: Hip fracture and acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) could increase mortality in patients with COPD. There are no data on the relationship between AE-COPD and hip fracture, which may significantly affect the prognosis of patients with COPD. Therefor..
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Gastroenterology
Proton pump inhibitor use is associated with hip fracture development: a nationwide population-based cohort study
Yang Won Min, Yeong Chan Lee, Kyunga Kim, Seungho Ryu, Kyoung Sub Hong, Han Ho Jeon, Yong Sung Kim, Jong Heon Park, Hee Jung Son, Poong-Lyul Rhee
Korean J Intern Med. 2020;35(5):1084-1093. Published online November 4, 2019
Background/Aims: Effect of proton pump inhibitor (PPI) use on the risk of hip fracture is controversial. This study aimed to clarify the association between PPI use and hip fracture risk using a large cohort.
Methods: This study recruited participants from the nationwide cohort (n = 1,025,340). Aft..
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