Cardiology
Efficacy of single-dose evolocumab injection in early-phase acute myocardial infarction: a retrospective single-center study
Yongcheol Kim, Ji Woong Roh, Oh-Hyun Lee, Seok-Jae Heo, Eui Im, Deok-Kyu Cho, Byeong-Keuk Kim
Korean J Intern Med. 2024;39(5):793-800. Published online June 24, 2024
Background/Aims: Achieving rapid reduction of low-density lipoprotein cholesterol (LDL-C) levels below 55 mg/dL in patients with acute myocardial infarction (AMI) can be challenging with statins alone. This single-center, retrospective study aimed to assess the impact of single-dose injection of evo..
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Expanding the therapeutic landscape: ezetimibe as non-statin therapy for dyslipidemia
Jeongmin Lee, Seung-Hwan Lee
Korean J Intern Med. 2023;38(6):797-809. Published online October 20, 2023
Dyslipidemia is a significant risk factor for atherosclerotic cardiovascular disease (ASCVD), and statins are the primary therapeutic options for reducing low-density lipoprotein cholesterol (LDL-C) levels. However, it can be challenging to achieve optimal LDL-C goals with statin monotherapy. Ezetim..
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Nephrology
Plasma oxalic acid and cardiovascular risk in end-stage renal disease patients: a prospective, observational cohort pilot study
Natalia Stepanova, Victoria Driianska, Lesya Korol, Lyudmyla Snisar, Larysa Lebed
Korean J Intern Med. 2022;37(1):167-178. Published online June 25, 2021
Background/Aims: It was hypothesized that oxalate might be strongly involved in atherogenesis and the inflammatory pathway that could result in an increased risk of cardiovascular disease (CVD) in end-stage renal disease (ESRD) patients. Therefore, this study aimed to address two primary research qu..
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Cardiology
Effects of cigarette smoking on blood lipids in Korean men: Cardiovascular and Metabolic Diseases Etiology Research Center cohort
Soo Kyoung Kim, Hyeon Chang Kim, Jee-Seon Shim, Dae Jung Kim
Korean J Intern Med. 2020;35(2):369-382. Published online December 18, 2019
Background/Aims: Cigarette smoking and abnormal blood lipids are major risk factors for cardiovascular disease. The results of previous studies on the relationship between cigarette smoking and dyslipidemia are controversial. In the present study, we investigated the independent association between ..
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Early efficacy and safety of statin therapy in Korean patients with hypercholesterolemia: Daegu and Gyeongbuk Statin Registry
Han Joon Bae, Yun-Kyeong Cho, Hyoung-Seob Park, Hyuck-Jun Yoon, Hyungseop Kim, Seongwook Han, Seung-Ho Hur, Yoon-Nyun Kim, Kwon-Bae Kim, Jae-Kean Ryu, Deug Young Nah, Chang-Wook Nam
Korean J Intern Med. 2020;35(2):342-350. Published online August 19, 2019
Background/Aims: To date, prospective data are limited on efficacy and safety profiles of statin therapy in Korean hypercholesterolemic patients. Hence, the aim of this study was to evaluate the practice patterns of statin therapy and its efficacy and safety through the prospective Daegu and Gyeong..
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Endocrinology-metabolism
Aromatase inhibitor use is a risk factor of carotid plaque presence in endocrine-responsive breast cancer patients
Da Hea Seo, Yongin Cho, Sujin Lee, Seho Park, Seung-Il Kim, Byeong Woo Park, Yumie Rhee
Korean J Intern Med. 2019;34(3):579-587. Published online August 25, 2017
Background/Aims: The aromatase inhibitors (AIs) are well known anti-hormonal therapy in endocrine-responsive breast cancer patients. It can lead to dyslipidemia and be the risk factor of cardiovascular disease due to low estrogen level. However, some recent studies comparing AIs with placebo have sh..
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The Contribution of Abdominal Obesity and Dyslipidemia to Metabolic Syndrome in Psychiatric Patients
Sung-Hwan Kim, Kiwon Kim, Mi Hyang Kwak, Hak Jin Kim, Hong-Sup Kim, Ki Hoon Han
Korean J Intern Med. 2010;25(2):168-173. Published online June 1, 2010
Background/AimsMetabolic syndrome is an emerging risk factor for cardiovascular disease. This study investigated the prevalence of metabolic syndrome among psychiatric patients in order to identify the dominant factors of metabolic syndrome. Methods
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The Efficacy and Safety of Ezetimibe and Low-Dose Simvastatin as a Primary Treatment for Dyslipidemia in Renal Transplant Recipients
Hye Eun Yoon, Joon Chang Song, Bok Jin Hyoung, Hyeon Seok Hwang, So Young Lee, Youn Joo Jeon, Bum Soon Choi, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2009;24(3):233-237. Published online August 26, 2009
Background/AimsThe efficacy and safety of a combination of ezetimibe and low-dose statin as primary treatment for dyslipidemia in renal transplant patients were evaluated prospectively. MethodsThe study enrolled 77 renal transplant recipients wi..
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