Gastroenterology / Review
Role of endoscopic ultrasound in the diagnosis and local ablative therapy of pancreatic neuroendocrine tumors
Yun Je Song, Jun Kyeong Lim, Jun-Ho Choi
Korean J Intern Med. 2025;40(2):170-180. Published online February 25, 2025
Advancements in diagnostic technology have led to the improved detection of pancreatic neuroendocrine tumors (PNETs) and thus to an increase in the number of reported cases. Endoscopic ultrasound (EUS) technology, including in combination with contrast-enhanced harmonic imaging, aids in distinguishi..
|
|
Cardiology / Review
2024 KSoLA consensus on secondary dyslipidemia
Hoyoun Won, Jae Hyun Bae, Hyunjung Lim, Minji Kang, Minjoo Kim, Sang-Hak Lee; on behalf of the Clinical Practice Guidelines Committee, Korean Society of Lipid and Atherosclerosis (KSoLA)
Korean J Intern Med. 2024;39(5):717-730. Published online August 30, 2024
Elevated blood cholesterol and triglyceride levels induced by secondary causes are frequently observed. The identification and appropriate handling of these causes are essential for secondary dyslipidemia treatment. Major secondary causes of hypercholesterolemia and hypertriglyceridemia include an u..
|
|
Gastroenterology / Review
Artificial intelligence in colonoscopy: from detection to diagnosis
Eun Sun Kim, Kwang-Sig Lee
Korean J Intern Med. 2024;39(4):555-562. Published online May 2, 2024
This study reviews the recent progress of artificial intelligence for colonoscopy from detection to diagnosis. The source of data was 27 original studies in PubMed. The search terms were “colonoscopy” (title) and “deep learning” (abstract). The eligibility criteria were: (1) the dependent varia..
|
|
Gastroenterology / Original Article
Diagnosis and management of acute colonic diverticulitis: results of a survey among Korean gastroenterologists
Jae Gon Lee, Yong Eun Park, Ji Young Chang, Hyun Joo Song, Duk Hwan Kim, Young Joo Yang, Byung Chang Kim, Shin Hee Lee, Myung-Won You, Seong-Eun Kim
Korean J Intern Med. 2023;38(5):672-682. Published online August 17, 2023
Background/Aims: Some management strategies for acute colonic diverticulitis remain controversial in Korean real-world practice because their clinical features differ from those in the West. This study aimed to investigate the opinions of Korean physicians regarding the diagnosis and treatment of ac..
|
|
Cardiology / Review
Role of echocardiography in acute pulmonary embolism
Jin Kyung Oh, Jae-Hyeong Park
Korean J Intern Med. 2023;38(4):456-470. Published online January 2, 2023
Although pulmonary embolism (PE)-related mortality rate has decreased because of prompt diagnosis and effective therapy use, acute PE remains a potentially lethal disease. Due to its increasing prevalence, clinicians should pay attention to diagnosing and managing patients with acute PE. Echocardiog..
|
|
Cardiology / Review
Obesity-related heart failure with preserved ejection fraction: diagnostic and therapeutic challenges
Mi-Hyang Jung, Mi-Seung Shin
Korean J Intern Med. 2023;38(2):157-166. Published online February 6, 2023
The prevalence of heart failure with preserved ejection fraction (HFpEF) has increased in recent decades. In particular, obesity-related HFpEF is a distinct and frequently encountered phenotype; however, its diagnosis is complex. Furthermore, the management of obesity-related HFpEF has not been esta..
|
|
Endocrinology-metabolism / Original Article
Diabetes screening in South Korea: a new estimate of the number needed to screen to detect diabetes
Kyoung Hwa Ha, Kyung Ae Lee, Kyung-Do Han, Min Kyong Moon, Dae Jung Kim
Korean J Intern Med. 2023;38(1):93-100. Published online November 24, 2022
Background/Aims: The Korean Diabetes Association (KDA) guidelines recommend adults aged ≥ 40 years and adults aged ≥ 30 years with diabetes risk factors for diabetes screening. This study aimed to determine the age threshold for diabetes screening in Korean adults.
Methods: This study was based o..
|
|
Pulmonology / Original Article
Diagnostic index for acute eosinophilic pneumonia without bronchoscopy in military smokers
Sunmin Park, Deokjae Han, Ji Eun Lee, Duck Hyun Ryu, Hyung-Jun Kim
Korean J Intern Med. 2022;37(2):377-386. Published online December 16, 2021
Background/Aims: Acute eosinophilic pneumonia (AEP) is common among military smokers; however, bronchoscopy is required for the diagnosis. We aimed to derive and validate a scoring system to diagnose AEP without bronchoscopy.
Methods: We conducted a retrospective study including patients diagnosed ..
|
|
Allergy / Original Article
Current practice for diagnosing immediate drug hypersensitivity reactions in Korea
Sung-Yoon Kang, Min-Suk Yang, Woo-Jung Song, Sang-Heon Cho
Korean J Intern Med. 2021;36(Suppl 1):S283-S296. Published online January 5, 2021
Background/Aims: Skin (STs) and drug provocation (DPTs) tests are essential for identifying the culprit drugs causing drug hypersensitivity reactions (DHRs). Several protocols have been developed for the identification of some culprit drugs, but they are neither thoroughly validated nor standardized..
|
|
Pulmonology / Original Article
Characteristics and risk factors associated with missed diagnosis in patients with smear-negative pulmonary tuberculosis
Se Hyun Kwak, Ji Soo Choi, Eun Hye Lee, Su Hwan Lee, Ah Young Leem, Sang Hoon Lee, Song Yee Kim, Kyung Soo Chung, Ji Ye Jung, Moo Suk Park, Young Sam Kim, Joon Chang, Young Ae Kang
Korean J Intern Med. 2021;36(Suppl 1):S151-S159. Published online August 20, 2020
Background/Aims: Delayed diagnosis and treatment of smear-negative pulmonary tuberculosis (TB) are major concerns for TB control. We evaluated characteristics of patients with smear-negative pulmonary TB who received a delayed diagnosis and identified risk factors that may have contributed to this d..
|
|
Geriatrics / Original Article
Validity of the Clinical Frailty Scale in Korean older patients at a geriatric clinic
Hee-Won Jung, Il-Young Jang, Ji Yeon Back, Seunghyun Park, Chan MI Park, Seung Jun Han, Eunju Lee
Korean J Intern Med. 2021;36(5):1242-1250. Published online December 30, 2020
Background/Aims: We aimed to assess the validity of the Korean translated version of the Clinical Frailty Scale (CFS) in determining the frailty status in geriatric outpatients.
Methods: The records of 123 ambulatory outpatients who had undergone CFS and comprehensive geriatric assessments (CGAs) i..
|
|
Pulmonology / Original Article
Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis
Ji-Hye Son, Jong-Uk Lee, Susie Chin, Eun-Suk Go, Jai-Seong Park, Hwa-Kyun Shin, Hun Soo Chang, Jong-Sook Park, Choon-Sik Park
Korean J Intern Med. 2021;36(4):914-923. Published online September 21, 2020
Background/Aims: Receptor tyrosine kinase-like orphan receptor 2 (ROR2) is a major regulator of Wnt signaling, which is involved in fibroblast dysfunction. Because its role has not been evaluated in idiopathic pulmonary fibrosis (IPF), we examined the clinical implications of ROR2 expression.
Metho..
|
|
Review
Clinical spectrum and diagnosis of diabetic neuropathies
Jeeyoung Oh
Korean J Intern Med. 2020;35(5):1059-1069. Published online August 28, 2020
Neuropathy is the most prevalent microvascular complication of diabetes mellitus; it encompasses distal symmetric polyneuropathy, autonomic neuropathy, radiculoplexus neuropathy, mononeuropathy, and treatment-induced neuropathy. The prevalence rate of diabetic neuropathy in Korea was reported to be ..
|
|
Review / Brief Communication
Current laboratory diagnosis of coronavirus disease 2019
Jihyang Lim, Jehoon Lee
Korean J Intern Med. 2020;35(4):741-748. Published online July 1, 2020
Coronavirus disease 2019 (COVID-19) emerged in December 2019 in Wuhan, China; it has since caused a pandemic, with more than 10,000 confirmed cases (> 800,000 tests) in Korea as of May 2020. Real-time reverse transcription polymerase chain reaction (RT-PCR) is currently the most commonly used method..
|
|
Pulmonology / Review
Latent tuberculosis infection: recent progress and challenges in South Korea
Doosoo Jeon
Korean J Intern Med. 2020;35(2):269-275. Published online February 28, 2020
Management of latent tuberculosis infection (LTBI) is a critical element in the elimination of tuberculosis (TB). However, the low positive predictive value of the current diagnostic tests and the low acceptance and completion rate of the isoniazid- based regimen are major barriers to the implementa..
|
|
Review
Consensus regarding diagnosis and management of atypical hemolytic uremic syndrome
Hajeong Lee, Eunjeong Kang, Hee Gyung Kang, Young Hoon Kim, Jin Seok Kim, Hee-Jin Kim, Kyung Chul Moon, Tae Hyun Ban, Se Won Oh, Sang Kyung Jo, Heeyeon Cho, Bum Soon Choi, Junshik Hong, Hae Il Cheong, Doyeun Oh
Korean J Intern Med. 2020;35(1):25-40. Published online January 2, 2020
Thrombotic microangiopathy (TMA) is defined by specific clinical characteristics, including microangiopathic hemolytic anemia, thrombocytopenia, and pathologic evidence of endothelial cell damage, as well as the resulting ischemic end-organ injuries. A variety of clinical scenarios have features of ..
|
|
Rheumatology / Original Article
Factors associated with time to diagnosis from symptom onset in patients with early rheumatoid arthritis
Soo-Kyoung Cho, Dam Kim, Soyoung Won, Jiyoung Lee, Chan-Bum Choi, Jung-Yoon Choe, Seung-Jae Hong, Jae-Bum Jun, Tae-Hwan Kim, Eunmi Koh, Hye-Soon Lee, Jisoo Lee, Dae-Hyun Yoo, Bo Young Yoon, Sang-Cheol Bae, Yoon-Kyoung Sung; Korean Observational Study Network for Arthritis (KORONA) Investigators
Korean J Intern Med. 2019;34(4):910-916. Published online December 15, 2017
Background/Aims: To identify the factors associated with time to diagnosis after symptom onset in patients with early rheumatoid arthritis (RA).
Methods: Early RA patients with ≤ 1 year of disease duration in the KORean Observational study Network for Arthritis (KORONA) database were included in t..
|
|
Review
Current status of pulmonary arterial hypertension in Korea
Albert Youngwoo Jang, Wook-Jin Chung
Korean J Intern Med. 2019;34(4):696-707. Published online July 1, 2019
Pulmonary arterial hypertension (PAH) is characterized by remodeling of the distal pulmonary arteries resulting in high pulmonary vascular resistance and, eventually, right ventricular heart failure. Although current advances in PAH therapy have improved outcomes, poor survival remains a reality wor..
|
|
Cardiology / Review
Chronic venous insufficiency and varicose veins of the lower extremities
Young Jin Youn, Juyong Lee
Korean J Intern Med. 2019;34(2):269-283. Published online October 26, 2018
Chronic venous insufficiency (CVI) of the lower extremities manifests itself in various clinical spectrums, ranging from asymptomatic but cosmetic problems to severe symptoms, such as venous ulcer. CVI is a relatively common medical problem but is often overlooked by healthcare providers because of ..
|
|
Gastroenterology / Review
Recent advances in the diagnosis and management of chronic pancreatitis
Chang-Il Kwon, Jae Hee Cho, Sung Hoon Choi, Kwang Hyun Ko, Temel Tirkes, Mark A. Gromski, Glen A. Lehman
Korean J Intern Med. 2019;34(2):242-260. Published online February 25, 2019
Chronic pancreatitis is a chronic condition characterized by pancreatic inflammation that causes fibrosis and the destruction of exocrine and endocrine tissues. Chronic pancreatitis is a progressive disease, and no physiological treatment is available to reverse its course. However, with advances in..
|
|
|