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Hemato-oncology
The effect of the dexamethasone, cytarabine, and cisplatin (DHAP) regimen on stem cell mobilization and transplant outcomes of patients with non-Hodgkin’s lymphoma who are candidates for up-front autologous stem cell transplantation
So Yeon Jeon, Ho-Young Yhim, Hee Sun Kim, Jeong-A Kim, Deok-Hwan Yang, Jae-Yong Kwak
Korean J Intern Med. 2018;33(6):1169-1181. Published online January 8, 2018
Background/Aims: Data on dexamethasone, cytarabine, and cisplatin (DHAP) as a mobilization regimen, compared to high-dose cyclophosphamide (HDC), for up-front autologous stem cell transplantation (ASCT) in non-Hodgkin’s lymphoma (NHL) is limited.
Methods: Consecutive patients with aggressive NHL ..
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Pulmonology
Prolonged low-dose cyclophosphamide treatment after pulse therapy attenuates lung injury in rats with paraquat intoxication
Jie Gao, Shunyi Feng, Yong Li
Korean J Intern Med. 2018;33(6):1137-1142. Published online May 31, 2018
Background/Aims: This study tested the hypothesis that prolonged low-dose cyclophosphamide (CTX) treatment after pulse therapy attenuate paraquat (PQ)-induced lung injury in rats.
Methods: PQ (25 mg/kg) was administered intraperitoneally to induce PQ-intoxicated rat model. The rats were randomly di..
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Cyclophosphamide therapy for secondary amyloidosis in a patient with juvenile idiopathic arthritis unresponsive to tumor necrosis factor α inhibitor therapy
Sun Ae Han, Young Min Yoon, Wan Soo Lee, Yun Sung Kim, Byung Chul Shin, Jong Hoon Chung, Hyun Lee Kim
Korean J Intern Med. 2016;31(3):601-604. Published online March 7, 2016
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Nephrology
The dose of cyclophosphamide for treating paraquat-induced rat lung injury
Jae-Sung Choi, Sung-Shick Jou, Mee-Hye Oh, Young-Hee Kim, Min-Ju Park, Hyo-Wook Gil, Ho-Yeon Song, Sae-Yong Hong
Korean J Intern Med. 2013;28(4):420-427. Published online July 1, 2013
Background/AimsCyclophosphamide (CP) is a promising treatment for severe cases of paraquat (PQ) poisoning. We investigated the effective dose of CP for mitigating PQ-induced lung injury. MethodsAdult male Sprague-Dawley rats were allocated into ..
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High-dose Versus Low-dose Cyclophosphamide in Combination with G-CSF for Peripheral Blood Progenitor Cell Mobilization
Jin Seok Ahn, Seonyang Park, Seock-Ah Im, Sung-Soo Yoon, Jong-Seok Lee, Byoung Kook Kim, Soo-Mee Bang, Eun Kyung Cho, Jae Hoon Lee, Chul Won Jung, Hugh Chul Kim, Chu Myung Seong, Moon Hee Lee, Chul Soo Kim, Keun Seok Lee, Jung Ae Lee, Myung-Ju Ahn
Korean J Intern Med. 2005;20(3):224-231. Published online September 30, 2005
BackgroundTo compare the mobilizing effects and toxicities of two different doses of cyclophosphamide (CY) plus lenograstim (glycosylated G-CSF), we performed a prospective randomized study by enrolling patients suffering with either high-risk Non-Hodgkin's lymphoma (NHL) or b..
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