Rheumatology
Epidemiology and risk factors associated with avascular necrosis in patients with autoimmune diseases: a nationwide study
Hsin-Lin Tsai, Jei-Wen Chang, Jen-Her Lu, Chin-Su Liu
Korean J Intern Med. 2022;37(4):864-876. Published online March 3, 2022
Background/Aims: Avascular necrosis (AVN) is a clinical condition characterized by the death of bone components due to interruption in the blood supply. This study aimed to investigate the epidemiology and determine the risk factors for AVN in patients with autoimmune diseases.
Methods: We conducte..
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Infectious diseases
Varicella zoster virus (VZV)-specific immunity and subclinical VZV reactivation in patients with autoimmune diseases
Kwang-Hoon Lee, Sungim Choi, Ji-Soo Kwon, Sung-Han Kim, Seong Yeon Park
Korean J Intern Med. 2021;36(4):992-1000. Published online June 15, 2021
Background/Aims: The risk of herpes zoster (HZ) is increased in patients with autoimmune diseases (AID), probably due to immunosuppressive therapy.
Methods: This prospective cross-sectional study investigated varicella zoster virus (VZV)-specific immunity in relation to subclinical VZV reactivation..
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Recent advances in the diagnosis and management of interstitial pneumonia with autoimmune features: the perspective of rheumatologists
Hong Ki Min, Se-Hee Kim, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2021;36(3):515-526. Published online February 8, 2021
Interstitial pneumonia with autoimmune feature (IPAF) is a recently established disease entity that is comprised of interstitial lung diseases with evidence of autoimmune features but that does not fulfill the criteria for definite autoimmune rheumatic diseases. The classification criteria for IPAF ..
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Rheumatology
Mutation of ten-eleven translocation-2 is associated with increased risk of autoimmune disease in patients with myelodysplastic syndrome
Yoon-Jeong Oh, Dong-Yeop Shin, Sang Mee Hwang, Sung-Min Kim, Kyongok Im, Hee Sue Park, Jung-Ah Kim, Yeong Wook Song, Ana Márquez, Javier Martín, Dong-Soon Lee, Jin Kyun Park
Korean J Intern Med. 2020;35(2):457-464. Published online October 25, 2019
Background/Aims: Myelodysplastic syndrome (MDS) is caused by genetic and epigenetic alteration of hematopoietic precursors and immune dysregulation. Approximately 20% of patients with MDS develop an autoimmune disease (AID). Here, we investigated whether particular genetic mutations are associated w..
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New insights into the role of renal resident cells in the pathogenesis of lupus nephritis
Seung-Ki Kwok, George C. Tsokos
Korean J Intern Med. 2018;33(2):284-289. Published online January 12, 2018
Systemic lupus erythematosus (SLE), an autoimmune disease of unknown etiology, is characterized by the production of autoantibodies and end-organ damage. Lupus nephritis affects up to 70% of patients with SLE and is the most critical predictor of morbidity and mortality. The immunopathogenesis of SL..
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Pulmonology
Treatment of connective tissue disease-associated interstitial lung disease: the pulmonologist’s point of view
So-My Koo, Soo-Taek Uh
Korean J Intern Med. 2017;32(4):600-610. Published online June 30, 2017
Interstitial lung disease (ILD) occurs in 15% of patients with collagen vascular disease (CVD), referred to as connective tissue disease (CTD). Despite advances in management strategies, ILD continues to be a significant cause of mortality in patients with CVD-associated ILD (CTD-ILD). There is a la..
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Hemato-oncology
Clinical manifestations of autoimmune disease-related non-Hodgkin lymphoma: a Korean single-center, retrospective clinical study
Young-Woo Jeon, Jae-Ho Yoon, Sung-Eun Lee, Ki-Seong Eom, Yoo-Jin Kim, Hee-Je Kim, Seok Lee, Chang-Ki Min, Jong Wook Lee, Woo-Sung Min, Seok-Goo Cho
Korean J Intern Med. 2015;31(5):944-952. Published online July 7, 2016
Background/Aims: Recently, large cohort studies regarding associations between autoimmune disease and lymphomas have been reported in a few Western countries. However, Asian data concerning autoimmune-related lymphomas are limited. Therefore, we evaluated the clinical characteristics and prognostic ..
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Autoimmune Chronic Pancreatitis Relapsing Despite the Maintenance Dose of Steroid
Dae Keun Pyun, Won Beom Choi, Myung Hwan Kim, Jae Pil Yun, Sang Su Lee, Dong Wan Seo, Sung Koo Lee
Korean J Intern Med. 2005;20(2):163-167. Published online June 30, 2005
Autoimmune chronic pancreatitis is a disease characterized by diffuse swelling of the pancreas, irregular narrowing of the main pancreatic duct and elevated levels of serum IgG, and lymphoplasmacytic infiltration is observed on histologic examination. Steroid therapy can dramatically reverse the ..
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