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Cardiology / Original Article
Explainable paroxysmal atrial fibrillation diagnosis using an artificial intelligence-enabled electrocardiogram
Yeongbong Jin, Bonggyun Ko, Woojin Chang, Kang-Ho Choi, Ki Hong Lee
Korean J Intern Med. 2025;40(2):251-261. Published online February 21, 2025
Background/Aims: Atrial fibrillation (AF) significantly contributes to global morbidity and mortality. Paroxysmal atrial fibrillation (PAF) is particularly common among patients with cryptogenic strokes or transient ischemic attacks and has a silent nature. This study aims to develop reliable artifi..
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Cardiology / Review
Screening and diagnosis of atrial fibrillation using wearable devices
Yoon Jung Park, Myung Hwan Bae
Korean J Intern Med. 2025;40(1):7-14. Published online May 3, 2024
In recent years, the development and use of various devices for the screening of atrial fibrillation (AF) have significantly increased. Such devices include 12-lead electrocardiogram (ECG), photoplethysmography systems, and single-lead ECG and ECG patches. This review outlines several studies that h..
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Cardiology / Original Article
Modified application of SAMe-TT2R2 scoring system in Asian patients with atrial fibrillation for the selection of oral anticoagulants
Seong Won Jeon, Nuri Lee, Ki Hong Lee, Minjeong Ha, Changhyun Kim, Yoo Ri Kim, Nam Sik Yoon, Hyung Wook Park
Korean J Intern Med. 2024;39(3):458-468. Published online January 30, 2024
Background/Aims: The SAMe-TT2R2 score is used for assessing anticoagulation control (AC) quality with warfarin. However, it is hard to apply SAMe-TT2R2 score in Asian patients with atrial fibrillation (AF), because it has not been proven in those populatio..
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Cardiology / Original Article
Exercise capacity and risk of incident atrial fibrillation in healthy adults
Ju Youn Kim, Soo Jin Cho, Juwon Kim, Tae-Wan Chung, Seung-Jung Park, Kyoung-Min Park, June Soo Kim, Young Keun On
Korean J Intern Med. 2023;38(6):872-878. Published online November 1, 2023
Background/Aims: Atrial fibrillation (AF) is a common arrhythmia and is associated with cardiovascular morbidity and mortality. It is important to identify and control the modifiable risk factors of AF. We aimed to examine the association of exercise capacity with the risk of incident AF within 3 ye..
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Cardiology / Review
Low-dose non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation
Ki Hong Lee, Hyung Wook Park
Korean J Intern Med. 2023;38(5):583-594. Published online September 1, 2023
In the last decade, non-vitamin K antagonist oral anticoagulants (NOACs), a new generation of OACs, were introduced to prevent thromboembolism in patients with atrial fibrillation. Although vitamin K-dependent anticoagulants have long been used as OACs, their inherent disadvantage of considerable bl..
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Cardiology / Review
Omega-3 fatty acids and atrial fibrillation
Ji Hye Huh, Sang-Ho Jo
Korean J Intern Med. 2023;38(3):282-289. Published online December 14, 2022
Although some clinical trials have demonstrated reduced incidence of cardiovascular disease with the use of omega-3 fatty acids, others have found an increased risk of atrial fibrillation (AF). AF is the most common sustained cardiac arrhythmia worldwide. It is associated with high morbidity and mor..
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Gastroenterology / Original Article
Safety of direct oral anticoagulants compared to warfarin in cirrhotic patients with atrial fibrillation
Seo Yeon Yoo, Eunju Kim, Gi-Byoung Nam, Danbi Lee, Ju Hyun Shim, Kang Mo Kim, Young-Suk Lim, Han Chu Lee, Young-Hwa Chung, Yung Sang Lee, Jonggi Choi
Korean J Intern Med. 2022;37(3):555-566. Published online January 26, 2022
Background/Aims: The safety of direct oral anticoagulants (DOACs) compared with warfarin in patients with both nonvalvular atrial fibrillation (AF) and clinically confirmed liver cirrhosis (LC) has not been well studied. We compared the risk of a major bleeding event between DOAC and warfarin treatm..
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Pulmonology / Original Article
Atrial fibrillation in critically ill patients who received prolonged mechanical ventilation: a nationwide inpatient report
Zhen Lin, Hedong Han, Wei Guo, Xin Wei, Zhijian Guo, Shujie Zhai, Shuai Li, Yiming Ruan, Fangyuan Hu, Dongdong Li, Jia He
Korean J Intern Med. 2021;36(6):1389-1401. Published online July 12, 2021
Background/Aims: To evaluate temporal trends of atrial fibrillation (AF) prevalence in critically ill patients who received prolonged mechanical ventilation (MV) in the United States.
Methods: We used the 2008 to 2014 National Inpatient Sample to compute the weighted prevalence of AF among hospital..
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Cardiology / Original Article
A prospective, observational study of rivaroxaban for stroke prevention in atrial fibrillation: the XANAP Korea
Jaemin Shim, Young Keun On, Sun U. Kwon, Gi-Byoung Nam, Moon-Hyoung Lee, Hyung-Wook Park, Keun-Sik Hong, Nam-Ho Kim, Pierre Amarenco, Seung-Woon Rha, Dong-Gu Shin, Joung-Ho Rha, Young-Hoon Kim
Korean J Intern Med. 2021;36(4):906-913. Published online June 11, 2021
Background/Aims: Atrial fibrillation (AF)-related stroke accounts for 20% of ischemic strokes. Rivaroxaban use in AF patients for preventing stroke and systemic embolism was approved in 2013 in Korea. This study was to investigate the safety and effectiveness of rivaroxaban use in Korean patients wi..
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Cardiology / Original Article
Impact of carotid atherosclerosis in CHA2DS2-VASc-based risk score on predicting ischemic stroke in patients with atrial fibrillation
Dong-Hyuk Cho, Jong-Il Choi, Jimi Choi, Yun Gi Kim, Suk-Kyu Oh, Hyungdon Kook, Kwang No Lee, Jaemin Shim, Seong-Mi Park, Wan Joo Shim, Young-Hoon Kim
Korean J Intern Med. 2021;36(2):342-351. Published online February 27, 2020
Background/Aims: Vascular disease is an established risk factor for stroke in patients with atrial fibrillation (AF), which is included in CHA2DS2-VASc score. However, the role of carotid atherosclerosis remains to be determined.
Methods: Three hundred-ten patients with AF who..
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Cardiology / Original Article
Comparative occurrence of ischemic stroke with the rhythm versus rate control strategy in a national prospective cohort of atrial fibrillation
Jae Guk Kim, Young Soo Lee, Ki-Woon Kang, Eue-Keun Choi, Myung-Jin Cha, Jung-Myung Lee, Jin-Bae Kim, Junbeom Park, Jin-Kyu Park, Tae-Hoon Kim, Jae-Sun Uhm, Jaemin Shim, Jun Kim, HyungWook Park, Changsoo Kim, Boyoung Joung
Korean J Intern Med. 2021;36(1):114-123. Published online October 14, 2019
Background/Aims: Comparative occurrence of ischemic stroke for rhythm versus rate control strategy in patients with non-valvular atrial fibrillation (NVAF) is still inconclusive. The purpose of this study was to investigate whether the rhythm control strategy is associated with a lower risk of isch..
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Cardiology / Original Article
Clinical significance of postoperative atrial arrhythmias in patients who underwent lung transplantation
Byung Gyu Kim, Jae-Sun Uhm, Pil-Sung Yang, Hee Tae Yu, Tae-Hoon Kim, Boyoung Joung, Hui-Nam Pak, Song Yee Kim, Moo Suk Park, Jin Gu Lee, Hyo Chae Paik, Moon-Hyoung Lee
Korean J Intern Med. 2020;35(4):897-905. Published online November 25, 2019
Background/Aims: Atrial arrhythmia (AA) occasionally occurs after lung transplantation (LT); however, risk factors for AA and their impact on clinical outcomes are inconsistent. We aimed to investigate the incidence, predisposing factors, and clinical outcomes of AA after LT.
Methods: We retrospect..
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Cardiology / Original Article
A prospective survey of the persistence of warfarin or NOAC in nonvalvular atrial fibrillation: a COmparison study of Drugs for symptom control and complication prEvention of Atrial Fibrillation (CODE-AF)
Hyeongsoo Kim, Young Soo Lee, Tae-Hoon Kim, Myung-Jin Cha, Jung Myung Lee, Junbeom Park, Jin-Kyu Park, Ki-Woon Kang, Jaemin Shim, Jae-Sun Uhm, Hyung Wook Park, Eue-Keun Choi, Jin-Bae Kim, Changsoo Kim, Jun Kim, Boyoung Joung
Korean J Intern Med. 2020;35(1):99-108. Published online April 25, 2019
Background/Aims: Efforts to reduce stroke in patients with atrial fibrillation (AF) have focused on increasing physician adherence to oral anticoagulant (OAC) guidelines; however, the high early discontinuation rate of vitamin K antagonists (VKAs) is a limitation. Although non-VKA OACs (NOACs) are m..
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Cardiology / Original Article
Predictors of acute myocarditis in complicated scrub typhus: an endemic province in the Republic of Korea
Jung Yeon Chin, Ki-Woon Kang, Kyung Min Moon, Jongwoo Kim, Yu Jeong Choi
Korean J Intern Med. 2018;33(2):323-330. Published online February 23, 2017
Background/Aims: Scrub typhus is known as a self-limited infectious disease. Cardiac complication is uncommon and usually not life-threatening. Until now, few cases of fulminant myocarditis by scrub typhus have been reported. So, we investigated incidence and predictors of acute myocarditis in sever..
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Cardiology / Original Article
Atrial conduction times and left atrial mechanical functions and their relation with diastolic function in prediabetic patients
Naile Eris Gudul, Turgut Karabag, Muhammet Rasit Sayin, Taner Bayraktaroglu, Mustafa Aydin
Korean J Intern Med. 2017;32(2):286-294. Published online December 6, 2016
Background/Aims: The aim of this study was to investigate atrial conduction times and left atrial mechanical functions, the noninvasive predictors of atrial fibrillation, in prediabetic patients with impaired fasting glucose (IFG) and impaired glucose tolerance (IGT).
Methods: Study included 59 pat..
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Cardiology / Review
Mean platelet volume: a potential biomarker of the risk and prognosis of heart disease
Dong-Hyun Choi, Seong-Ho Kang, Heesang Song
Korean J Intern Med. 2016;31(6):1009-1017. Published online October 24, 2016
Platelets are essential for progression of atherosclerotic lesions, plaque destabilization, and thrombosis. They secrete and express many substances that are crucial mediators of coagulation, inflammation, and atherosclerosis. Mean platelet volume (MPV) is a precise measure of platelet size, and is ..
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Letter to the editor
Series with complete resolution of left atrial appendage thrombi with apixaban in elderly patients
Sang Hoon Lee, Seongwook Han
Korean J Intern Med. 2016;31(2):396-398. Published online February 12, 2016
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Cardiology / Original Article
Interatrial septal thickness as a marker of structural and functional remodeling of the left atrium in patients with atrial fibrillation
Hong Euy Lim, Jin Oh Na, Sung Il Im, Cheol Ung Choi, Seong Hwan Kim, Jin Won Kim, Eung Ju Kim, Seong Woo Han, Seung-Woon Rha, Chang Gyu Park, Hong Seog Seo, Dong Joo Oh, Chun Hwang
Korean J Intern Med. 2015;30(6):808-820. Published online October 30, 2015
Background/Aims: There have been reports that interatrial septal (IAS) thickness is increased in patients with atrial fibrillation (AF). This study was performed to investigate whether IAS thickness determined by transthoracic echocardiography (TTE) represents the amount of left atrium (LA) structur..
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Case Report
Electrocardiographic artefacts mimicking atrial tachycardia resulted in unnecessary diagnostic and therapeutic measures
Shams Y-Hassan, Christer Sylvén
Korean J Intern Med. 2013;28(2):224-230. Published online February 27, 2013
Electrocardiographic (ECG) artefacts may closely simulate both supraventricular and ventricular tachycardias. We describe a case initially diagnosed as rapid atrial fibrillation, based on 12-lead surface ECG (especially the limb leads) and monitor tracing. The arrhythmia was resistant to beta blo..
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Original Article
Remodeling of Ion Channel Expression in Patients with Chronic Atrial Fibrillation and Mitral Valvular Heart Disease
Seil Oh, Ki-Bong Kim, Hyuk Ahn, Hyun-Ju Cho, Yun-Shik Choi
Korean J Intern Med. 2010;25(4):377-385. Published online November 27, 2010
Background/AimsUnderlying cardiac pathology and atrial fibrillation (AF) affect the molecular remodeling of ion channels in the atria. Changes in the expression of these molecules have not been demonstrated in Korean patients with mitral valvular heart disease. Thus, the purp..
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