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Rheumatology
Atorvastatin inhibits osteoclast differentiation by suppressing NF-κB and MAPK signaling during IL-1β-induced osteoclastogenesis
Won-Seok Lee, Eun-Gyeong Lee, Myung-Soon Sung, Yun-Jung Choi, Wan-Hee Yoo
Korean J Intern Med. 2018;33(2):397-406. Published online March 28, 2017
Background/Aims: To define the effect of statins on interleukin 1β (IL-1β)-induced osteoclastogenesis and elucidate the underlying mechanisms.
Methods: Bone marrow cells were obtained from 5-week-old male ICR (Institute for Cancer Research) mice, and they were cultured to differentiate them into ..
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Comparative Study of Low Doses of Rosuvastatin and Atorvastatin on Lipid and Glycemic Control in Patients with Metabolic Syndrome and Hypercholesterolemia
Jong-Seon Park, Young-Jo Kim, Ji-Yong Choi, Yoon-Nyun Kim, Teck-Jong Hong, Dong-Soo Kim, Ki-Young Kim, Myung-Ho Jeong, Jei-Keon Chae, Seok-Kyu Oh, In-Whan Seong
Korean J Intern Med. 2010;25(1):27-35. Published online February 26, 2010
Background/AimsThis multicenter, open-labeled, randomized trial was performed to compare the effects of rosuvastatin 10 mg and atorvastatin 10 mg on lipid and glycemic control in Korean patients with nondiabetic metabolic syndrome. MethodsIn tot..
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Flexible Initial Dosing of Atorvastatin Based Upon Initial Low-Density Lipoprotein Cholesterol Levels in Type 2 Diabetic Patients
Korean J Intern Med. 2008;23(1):22-29. Published online March 20, 2008
Background/AimsWe used flexible starting doses and early titration of atorvastatin to determine the rate of achievement of a low-density lipoprotein cholesterol (LDL-C) target for hyperlipidemic patients with type 2 diabetes mellitus. Me.. </div>
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