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Nephrology
A retrospective study on the efficacy of Roxadustat in peritoneal dialysis patients with erythropoietin hyporesponsiveness
Jie Liu, Shuang Li, Fan Yang, Tianyu Li, Rui Li, Yousuf Waheed, Chen Meng, Shulin Li, Kun Liu, Yanshan Tong, Haisheng Xu, Chuankuo Tian, Xinglei Zhou
Korean J Intern Med. 2024;39(3):488-500. Published online April 23, 2024
Background/Aims: Roxadustat, an oral medication for treating renal anemia, is a hypoxia-inducible factor prolyl hydroxylase inhibitor used for regulating iron metabolism and promoting erythropoiesis. To investigate the efficacy and safety of roxadustat in patients undergoing peritoneal dialysis (PD)..
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The role of roxadustat in chronic kidney disease patients complicated with anemia
Jie Liu, Fan Yang, Yousuf Waheed, Shulin Li, Kun Liu, Xinglei Zhou
Korean J Intern Med. 2023;38(2):147-156. Published online January 2, 2023
The incidence of chronic kidney disease (CKD) is increasing worldwide and the current prevalence rate is 13.4%. There are > 120 million CKD patients in China and this number is expected to increase. One of the main abnormalities in patients with CKD and kidney impairment is decreased synthesis of er..
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Gastroenterology
Helicobacter pylori infection and iron deficiency in non-elderly adults participating in a health check-up program
Jun Yeop Lee, Sung Eun Kim, Seun Ja Park, Moo In Park, Won Moon, Jae Hyun Kim, Kyoungwon Jung
Korean J Intern Med. 2022;37(2):304-312. Published online December 16, 2021
Background/Aims: Helicobacter pylori infection is presumably associated with iron deficiency and iron deficiency anemia (IDA). This study aimed to evaluate the relationship between H. pylori infection and the decline in iron stores in non-elderly adults during their health check-ups.
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Cardiology
Pre-discharge anemia as a predictor of adverse clinical outcomes in patients with acute decompensated heart failure
Min Chul Kim, Kye Hun Kim, Jae Yeong Cho, Ki Hong Lee, Doo Sun Sim, Hyun Ju Yoon, Nam Sik Yoon, Young Joon Hong, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Myung Ho Jeong, Jeong Gwan Cho, Jong Chun Park
Korean J Intern Med. 2019;34(3):549-558. Published online March 23, 2018
Background/Aims: The impact of the timing of anemia during hospitalization on future clinical outcomes after surviving discharge from an index heart failure (HF) has been poorly studied in patients with acute decompensated heart failure (ADHF).
Methods: A total of 384 surviving patients with acute ..
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Gastroenterology
Should asymptomatic young men with iron deficiency anemia necessarily undergo endoscopy?
Nam Hee Kim, Jung Ho Park, Dong Il Park, Chong Il Sohn, Kyuyong Choi, Yoon Suk Jung
Korean J Intern Med. 2018;33(6):1084-1092. Published online January 5, 2018
Background/Aims: There has been no evidence for the necessity of endoscopy in asymptomatic young men with iron deficiency anemia (IDA). To determine whether endoscopy should be recommended in asymptomatic young men with IDA, we compared the prevalence of gastrointestinal (GI) lesions between young m..
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Hemato-oncology
Recent advances in treatment of aplastic anemia
Seung Hwan Shin, Sung Eun Lee, Jong Wook Lee
Korean J Intern Med. 2014;29(6):713-726. Published online October 31, 2014
Recent advances in the treatment of aplastic anemia (AA) made most of patients to expect to achieve a long-term survival. Allogeneic stem cell transplantation (SCT) from HLA-matched sibling donor (MSD-SCT) is a preferred first-line treatment option for younger patients with severe or very severe AA,..
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Cardiology
Effect of anemia correction on left ventricular structure and filling pressure in anemic patients without overt heart disease
In-Jeong Cho, Yeung Chul Mun, Ki Hwan Kwon, Gil Ja Shin
Korean J Intern Med. 2014;29(4):445-453. Published online June 27, 2014
Background/Aims: There are few data on the effects of low hemoglobin levels on the left ventricle (LV) in patients without heart disease. The objective of this study was to document changes in the echocardiographic variables of LV structure and function after the correction of anemia without signif..
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What caused hemolytic anemia and colicky abdominal pain? Lead!
Se Heon Chang, Seon Bin Yoon, Jae Woong Lee, Duk Joo Lee
Korean J Intern Med. 2013;28(4):504-506. Published online July 1, 2013
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Serum Prohepcidin Levels in Helicobacter Pylori Infected Patients with Iron Deficiency Anemia
Sun-Young Lee, Eun Young Song, Yeo Min Yun, So Young Yoon, Yo Han Cho, Sung-Yong Kim, Mark Hong Lee
Korean J Intern Med. 2010;25(2):195-200. Published online June 1, 2010
Background/AimsHelicobacter pylori (H. pylori) infection appears to subvert the human iron regulatory mechanism and thus upregulates hepcidin, resulting in unexplained iron-deficiency anemia (IDA). We evaluated serum prohepcidin levels before ..
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IGF-1 is an Independent Risk Factor for Anemia in Diabetic Pre-dialysis Patients
Do-Hyoung Kim, Tae-Young Kim, Sun-Min Kim, Soo-Jeong Yoo, Dong-Jin Oh, Suk-Hee Yu
Korean J Intern Med. 2007;22(3):186-191. Published online September 30, 2007
BackgroundWe investigated whether the presence of diabetes mellitus (DM) was related to the degree of the anemia in predialytic patients with renal failure and what was the most relevant factor for anemia in patients with chronic kidney disease (CKD) from DM (DM-CKD).
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