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Rheumatology
Effectiveness of Korean Red Ginseng on fatigue in patients with rheumatic diseases: a randomized, double-blind, placebo-controlled study
Soo-Kyung Cho, Yeo-Jin Song, Jung-Yong Han, Hye Won Kim, Eunwoo Nam, Yoon-Kyoung Sung
Korean J Intern Med. 2024;39(4):680-690. Published online April 5, 2024
Background: To evaluate the effectiveness of Korean Red Ginseng (KRG) in managing fatigue in Korean patients with rheumatic diseases
Methods: Patients were randomly assigned to KRG (2 g/day, n = 60) or placebo (n = 60) groups for 12 weeks of blind phase and then open-label KRG from weeks 12 to 24 (..
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Comparative effectiveness of JAK inhibitors and biologic disease-modifying antirheumatic drugs in patients with rheumatoid arthritis
Soo-Kyung Cho, Hyoungyoung Kim, Yeo-Jin Song, Hye Won Kim, Eunwoo Nam, Shin-Seok Lee, Hye-Soon Lee, Sung-Hoon Park, Yeon-Ah Lee, Min-Chan Park, Sung Hae Chang, Hyoun-Ah Kim, Seung-Ki Kwok, Hae-Rim Kim, Hyun-Sook Kim, Bo Young Yoon, Wan-Sik Uhm, Yong-Gil Kim, Jae Hoon Kim, Jisoo Lee, Jeongim Choi, Yoon-Kyoung Sung
Korean J Intern Med. 2023;38(4):546-556. Published online June 20, 2023
Background/Aims: We aimed to compare the effectiveness and safety of Janus kinase inhibitors (JAKi) vs. biologic disease- modifying antirheumatic drugs (bDMARD) in Korean patients with rheumatoid arthritis (RA) who had an inadequate response to conventional synthetic DMARDs.
Methods: A quasi-exper..
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Clinical influences of anticentromere antibody on primary Sjögren’s syndrome in a prospective Korean cohort
Youngjae Park, Jennifer Lee, Jung Hee Koh, Jung Yoon Choe, Yoon-Kyoung Sung, Shin-Seok Lee, Ji-Min Kim, Sung-Hwan Park, Seung-Ki Kwok
Korean J Intern Med. 2021;36(6):1492-1503. Published online August 24, 2020
Background/Aims: This study was performed to clarify inf luences of anticentromere antibody (ACA) on clinical phenotypes of primary Sjögren’s syndrome (pSS) patients in Korea. Methods: We assessed 318 patients who met the 2016 American College of Rheumatology/ European League Against Rheumatism cla..
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The usefulness of trabecular bone score in patients with ankylosing spondylitis
Seoung Wan Nam, Yoon-Kyoung Sung, Dam Kim, Soo-Kyung Cho, Yoonah Song, Yun Young Choi, Yongjin Sim, Tae-Hwan Kim
Korean J Intern Med. 2021;36(5):1211-1220. Published online June 30, 2020
Backgrounds/Aims: This study was performed to reveal the usefulness of the trabecular bone score (TBS) in assessing bone strength in patients with ankylosing spondylitis (AS) in comparison with dual-energy X-ray absorptiometry (DXA) methods.
Methods: A total of 215 AS patients (75.8% male) were enr..
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Developing the Korean Educational Needs Assessment Tool (Korean ENAT) in rheumatoid arthritis: cross-cultural validation using Rasch analysis
Yoon-Kyoung Sung, Hyoungyoung Kim, Sung Joo Cha, Sae-Hyung Kim, Mwidimi Ndosi, Soo-Kyung Cho
Korean J Intern Med. 2021;36(4):1014-1022. Published online October 30, 2020
Background/Aims: This study was performed to undertake cross-cultural adaptation and validation of the Educational Needs Assessment Tool (ENAT) in rheumatoid arthritis (RA) for use in Korea.
Methods: The study involved two main phases: cross-cultural adaptation of the ENAT from English into Korean,..
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Recommendations for the management of patients with systemic rheumatic diseases during the coronavirus disease pandemic
Mi Ryoung Seo, Ji-Won Kim, Eun-Jung Park, Seung Min Jung, Yoon-Kyoung Sung, Hyungjin Kim, Gunwoo Kim, Hyun-Sook Kim, Myeung-Su Lee, Jisoo Lee, Ji An Hur, Bum Sik Chin, Joong Sik Eom, Han Joo Baek; The Korean College of Rheumatology working group
Korean J Intern Med. 2020;35(6):1317-1332. Published online September 15, 2020
Patients with systemic rheumatic diseases (SRD) are vulnerable for coronavirus disease (COVID-19). The Korean College of Rheumatology recognized the urgent need to develop recommendations for rheumatologists and other physicians to manage patients with SRD during the COVID-19 pandemic. The working g..
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The use of biological disease-modifying antirheumatic drugs for inflammatory arthritis in Korea: results of a Korean Expert Consensus
Eun-Jung Park, Hyungjin Kim, Seung Min Jung, Yoon-Kyoung Sung, Han Joo Baek, Jisoo Lee
Korean J Intern Med. 2020;35(1):41-59. Published online January 2, 2020
Biological disease-modifying antirheumatic drugs (bDMARDs) are highly effective agents for the treatment of inf lammatory arthritis; however, they also possess a potential risk for serious infection. Recently, with the rapid expansion of the bDMARDs market in Korea, reports of serious adverse events ..
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Rheumatology
Treatment patterns of knee osteoarthritis patients in Korea
Ha-Rim Park, Soo-Kyung Cho, Seul Gi Im, Sun-Young Jung, Dalho Kim, Eun Jin Jang, Yoon-Kyoung Sung
Korean J Intern Med. 2019;34(5):1145-1153. Published online March 21, 2018
Background/Aims: To evaluate the treatment patterns of knee osteoarthritis (OA) patients in South Korea.
Methods: Using the Korean nationwide claims database, all knee OA patients in Korea during 2014 were identified by the knee OA diagnostic code (M17) or any OA diagnostic code (M15 to M19) in com..
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A paradigm shift in studies based on rheumatoid arthritis clinical registries
Soo-Kyung Cho, Yoon-Kyoung Sung
Korean J Intern Med. 2019;34(5):974-981. Published online February 18, 2019
Clinical research is the study of aspects of patient health or illness that are closely related to clinical practice. In the late 20th and early 21th century, outcomes for patients with rheumatoid arthritis (RA) improved dramatically due to breakthroughs in new drugs. Patient-reported outcome measur..
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Rheumatology
Factors associated with time to diagnosis from symptom onset in patients with early rheumatoid arthritis
Soo-Kyoung Cho, Dam Kim, Soyoung Won, Jiyoung Lee, Chan-Bum Choi, Jung-Yoon Choe, Seung-Jae Hong, Jae-Bum Jun, Tae-Hwan Kim, Eunmi Koh, Hye-Soon Lee, Jisoo Lee, Dae-Hyun Yoo, Bo Young Yoon, Sang-Cheol Bae, Yoon-Kyoung Sung; Korean Observational Study Network for Arthritis (KORONA) Investigators
Korean J Intern Med. 2019;34(4):910-916. Published online December 15, 2017
Background/Aims: To identify the factors associated with time to diagnosis after symptom onset in patients with early rheumatoid arthritis (RA).
Methods: Early RA patients with ≤ 1 year of disease duration in the KORean Observational study Network for Arthritis (KORONA) database were included in t..
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Systemic review: agreement between the latent tuberculosis screening tests among patients with rheumatic diseases
Junhee Pyo, Soo-Kyung Cho, Dam Kim, Yoon-Kyoung Sung
Korean J Intern Med. 2018;33(6):1241-1251. Published online December 28, 2017
Background/Aims: To estimate the level of agreement and positivity rates of latent tuberculosis infection (LTBI) tests prior to the use of tumor necrosis factor (TNF) inhibitors in relation to underlying rheumatic diseases and endemic tuberculosis levels.
Methods: The Ovid-Medline, Embase, and Coch..
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Isoniazid treatment for latent tuberculosis infection is tolerable for rheumatoid arthritis patients receiving tumor necrosis factor inhibitor therapy
Yoon-Kyoung Sung, Soo-Kyung Cho, Dam Kim, Soyoung Won, Chan-Bum Choi, Tae-Hwan Kim, Jae-Bum Jun, Dae-Hyun Yoo, Sang-Cheol Bae
Korean J Intern Med. 2018;33(5):1016-1024. Published online March 13, 2017
Background/Aims: To evaluate the impact of isoniazid (INH) treatment for latent tuberculosis infection (LTBI) on the development of liver function test (LFT) abnormality and the persistence of tumor necrosis factor (TNF) inhibitors in rheumatoid arthritis (RA) patients.
Methods: We retrospectively ..
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Impact of early diagnosis on functional disability in rheumatoid arthritis
Dam Kim, Chan-Bum Choi, Jiyoung Lee, Soo-Kyung Cho, Soyoung Won, So-Young Bang, Hoon-Suk Cha, Jung-Yoon Choe, Won Tae Chung, Seung-Jae Hong, Jae-Bum Jun, Young Ok Jung, Jinseok Kim, Seong-Kyu Kim, Tae-Hwan Kim, Tae-Jong Kim, Eunmi Koh, Hye-Soon Lee, Jaejoon Lee, Jisoo Lee, Sang-Heon Lee, Shin-Seok Lee, Sung Won Lee, Seung-Cheol Shim, Dae-Hyun Yoo, Bo Young Yoon, Yoon-Kyoung Sung, Sang-Cheol Bae; KORONA investigators
Korean J Intern Med. 2017;32(4):738-746. Published online September 13, 2016
Background/Aims: To determine whether early diagnosis is beneficial for functional status of various disease durations in rheumatoid arthritis (RA) patients.
Methods: A total of 4,540 RA patients were enrolled as part of the Korean Observational Study Network for Arthritis (KORONA). We defined earl..
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Prevalence and possible causes of hypouricemia at a tertiary care hospital
Chang-Nam Son, Ji-Min Kim, Sang-Hyon Kim, Soo-Kyung Cho, Chan-Bum Choi, Yoon-Kyoung Sung, Tae-Hwan Kim, Sang-Cheol Bae, Dae-Hyun Yoo, Jae-Bum Jun
Korean J Intern Med. 2016;31(5):971-976. Published online March 9, 2016
Background/Aims: We aimed to investigate the prevalence and possible causes of hypouricemia in the Korean population and to compare our findings with published results of other populations.
Methods: We examined the serum uric acid levels of 30,757 subjects who had their uric acid values measured at..
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SKI306X inhibition of glycosaminoglycan degradation in human cartilage involves down-regulation of cytokine-induced catabolic genes
Choong Hyeok Choi, Tae-Hwan Kim, Yoon-Kyoung Sung, Chan-Bum Choi, Young-In Na, Hunseung Yoo, Jae-Bum Jun
Korean J Intern Med. 2014;29(5):647-655. Published online August 28, 2014
Background/Aims: SKI306X, a mixed extract of three herbs, Clematis mandshurica (CM), Prunella vulgaris (PV), and Trichosanthes kirilowii (TK), is chondroprotective in animal models of osteoarthritis (OA). The objectives of this study were to invest..
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Are glucocorticoid-induced osteoporosis recommendations suffi cient to determine antiosteoporotic treatment for patients with rheumatoid arthritis?
Joo-Hyun Lee, Soo-Kyung Cho, Minkyung Han, Dam Kim, Sang-Cheol Bae, Yoon-Kyoung Sung
Korean J Intern Med. 2014;29(4):509-515. Published online June 27, 2014
Background/Aims: We investigated diff erences in identifying candidates for antiosteoporotic treatment in rheumatoid arthritis (RA) patients according to two available clinical guidelines.
Methods: We prospectively enrolled 100 female patients aged 50 years or older with RA who visited Hanyang Uni..
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