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Pulmonology
Clinical characteristics of patients with COVID-19 vaccine-related pneumonitis: a case series and literature review
Ji Young Park, Joo-Hee Kim, Sunghoon Park, Yong Il Hwang, Hwan Il Kim, Seung Hun Jang, Ki-Suck Jung, Yong Kyun Kim, Hyun Ah Kim, In Jae Lee
Korean J Intern Med. 2022;37(5):989-1001. Published online August 22, 2022
Background/Aims: Pulmonary toxicities of coronavirus disease 2019 (COVID-19) vaccination are exceedingly rare. However, there are a few reported cases after mRNA vaccination, especially from Asian countries. The purpose of this study was to report the clinical characteristics of patients with COVID-..
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Nephrology
Human kidney organoids model the tacrolimus nephrotoxicity and elucidate the role of autophagy
Jin Won Kim, Sun Ah Nam, Eunjeong Seo, Jong Young Lee, Dohui Kim, Ji Hyeon Ju, Sun Woo Lim, Hong Lim Kim, Hyung Wook Kim, Chul Woo Yang, Jin Kim, Dong Sung Kim, Yong Kyun kim
Korean J Intern Med. 2021;36(6):1420-1436. Published online July 27, 2021
Background/Aims: Tacrolimus has been used as an immunosuppressive agent in organ transplantation. Despite the therapeutic benefits, tacrolimus’s use is limited due to its nephrotoxicity. To reduce tacrolimus nephrotoxicity, effective humanized experimental models may be helpful. Here, we modeled t..
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Pulmonology
Changes in respiratory virus infection trends during the COVID-19 pandemic in South Korea: the effectiveness of public health measures
Ji Young Park, Hwan Il Kim, Joo-Hee Kim, Sunghoon Park, Yong Il Hwang, Seung Hun Jang, Yong Kyun Kim, Ki-Suck Jung
Korean J Intern Med. 2021;36(5):1157-1168. Published online August 18, 2021
Background/Aims: Studies on the effectiveness of public health measures to prevent respiratory virus transmission in real-world settings are lacking. We investigated the effectiveness of universal mask use and adherence to other personal preventive measures on the changing viral respiratory infectio..
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Nephrology
Low parathyroid hormone level predicts infection-related mortality in incident dialysis patients: a prospective cohort study
Yu Ah Hong, Jeong Ho Kim, Yong Kyun Kim, Yoon Kyung Chang, Cheol Whee Park, Suk Young Kim, Yon Su Kim, Shin-Wook Kang, Nam-Ho Kim, Yong-Lim Kim, Chul Woo Yang
Korean J Intern Med. 2020;35(1):160-170. Published online October 28, 2019
Background/Aims: Parathyroid hormone (PTH) is an important factor influencing immunologic dysfunction, but the effect of PTH level on infection-related outcomes remains unclear in incident dialysis.
Methods: We evaluated a multicenter prospective cohort study of 1,771 incident dialysis patients (1,..
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Notch signaling in the collecting duct regulates renal tubulointerstitial fibrosis induced by unilateral ureteral obstruction in mice
Arum Choi, Sun Ah Nam, Wan-Young Kim, Sang Hee Park, Hyang Kim, Chul Woo Yang, Jin Kim, Yong Kyun Kim
Korean J Intern Med. 2018;33(4):774-782. Published online May 26, 2017
Background/Aims: Mind bomb-1 (Mib1) encodes an E3 ubiquitin ligase, which is required for the initiation of Notch signaling. Recently, it was demonstrated that the renal collecting duct plays an important role in renal fibrosis. Here, we investigated the role of Notch signaling in renal fibro..
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Applications of kidney organoids derived from human pluripotent stem cells
Yong Kyun Kim, Sun Ah Nam, Chul Woo Yang
Korean J Intern Med. 2018;33(4):649-659. Published online June 28, 2018
The establishment of protocols to differentiate kidney organoids from human pluripotent stem cells provides potential applications of kidney organoids in regenerative medicine. Modeling of renal diseases, drug screening, nephrotoxicity testing of compounds, and regenerative therapy are attractive ap..
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Minimal change nephrotic syndrome showing complete remission after resection of a neurofibroma in a type I neurofibromatosis patient
Ji In Hyun, Ji Won Min, Hye Min Lee, Yong Kyun Kim, Eu Jin Choi, Ho Cheol Song
Korean J Intern Med. 2017;32(1):186-189. Published online March 8, 2016
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Nephrology
The impact of high serum bicarbonate levels on mortality in hemodialysis patients
Kyung Yoon Chang, Hyung Wook Kim, Woo Jeong Kim, Yong Kyun Kim, Su-Hyun Kim, Ho Chul Song, Young Ok Kim, Dong Chan Jin, Euy Jin Choi, Chul Woo Yang, Yong-Lim Kim, Nam-Ho Kim, Shin-Wook Kang, Yon-Su Kim, Young Soo Kim
Korean J Intern Med. 2017;32(1):109-116. Published online April 5, 2016
Background/Aims: The optimal serum bicarbonate level is controversial for patients who are undergoing hemodialysis (HD). In this study, we analyzed the impact of serum bicarbonate levels on mortality among HD patients. Methods: Prevalent HD patients were selected from the Clinical Research Center re..
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The impact of blood flow rate during hemodialysis on all-cause mortality
Kyung Yoon Chang, Su-Hyun Kim, Young Ok Kim, Dong Chan Jin, Ho Chul Song, Euy Jin Choi, Yong-Lim Kim, Yon-Su Kim, Shin-Wook Kang, Nam-Ho Kim, Chul Woo Yang, Yong Kyun Kim
Korean J Intern Med. 2016;31(6):1131-1139. Published online February 22, 2016
Background/Aims: Inadequacy of dialysis is associated with morbidity and mortality in chronic hemodialysis (HD) patients. Blood flow rate (BFR) during HD is one of the important determinants of increasing dialysis dose. However, the optimal BFR is unclear. In this study, we investigated the impact o..
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The impact of high-flux dialysis on mortality rates in incident and prevalent hemodialysis patients
Hyung Wook Kim, Su-Hyun Kim, Young Ok Kim, Dong Chan Jin, Ho Chul Song, Euy Jin Choi, Yong-Lim Kim, Yon-Su Kim, Shin-Wook Kang, Nam-Ho Kim, Chul Woo Yang, Yong Kyun Kim
Korean J Intern Med. 2014;29(6):774-784. Published online October 31, 2014
Background/Aims: The effect of high-flux (HF) dialysis on mortality rates could vary with the duration of dialysis. We evaluated the effects of HF dialysis on mortality rates in incident and prevalent hemodialysis (HD) patients.
Methods: Incident and prevalent HD patients were selected from the Cli..
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Pleural and pericardial empyema in a patient with continuous ambulatory peritoneal dialysis peritonitis
Jong Hoon Lee, Young Sun Noh, Youn Hee Lee, In-Ae Jang, Ho Chul Song, Euy Jin Choi, Yong Kyun Kim
Korean J Intern Med. 2013;28(5):626-627. Published online August 14, 2013
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Natural History and Renal Pathology in Patients with Isolated Microscopic Hematuria
Byung Soo Kim, Yong Kyun Kim, Young Shin Shin, Young Ok Kim, Ho Cheol Song, Yong Soo Kim, Euy Jin Choi
Korean J Intern Med. 2009;24(4):356-361. Published online November 27, 2009
Background/AimsNo definite conclusions have been reached about the natural history of patients with isolated microscopic hematuria (IMH). In this study, we observed the natural history of patients with IMH and examined factors related to a pathologic diagnosis and subsequent p..
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