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Gastroenterology
The role of PD-1/PD-L1 pathway in ulcerative colitis and changes following tonsil-derived mesenchymal stem cells treatment
Eun Mi Song, Yang Hee Joo, Sung-Ae Jung, Ju-Ran Byeon, A-Reum Choe, Yehyun Park, Chung Hyun Tae, Chang Mo Moon, Seong-Eun Kim, Hye-Kyung Jung, Ki-Nam Shim
Korean J Intern Med. 2024;39(6):917-930. Published online November 1, 2024
Background/Aims: The programmed death 1 (PD-1)/programmed death-ligand 1 (PD-L1) pathway has not been fully evaluated in inflammatory bowel disease. We evaluated PD-1/PD-L1 levels in patients with ulcerative colitis (UC) and their significance in tonsil-derived mesenchymal stem cells (TMSCs) treatme..
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Clinical outcomes of acute upper gastrointestinal bleeding according to the risk indicated by Glasgow-Blatchford risk score-computed tomography score in the emergency room
Hyun Ae Lee, Hye-Kyung Jung, Tae Oh Kim, Ju-Ran Byeon, Eui-Sun Jeong, Hyun-Ji Cho, Chung Hyun Tae, Chang Mo Moon, Seong-Eun Kim, Ki-Nam Shim, Sung-Ae Jung
Korean J Intern Med. 2022;37(6):1176-1185. Published online November 1, 2022
Background/Aims: Acute upper gastrointestinal (UGI) bleeding is a significant emergency situation with a mortality rate of 2% to 10%. Therefore, initial risk stratification is important for proper management. We aimed to evaluate the role of contrast-enhanced multidetector computed tomography (MDCT)..
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Development, validation, and application of a novel tool to measure disease-related knowledge in patients with inflammatory bowel disease
Hyuk Yoon, Suk-Kyun Yang, Hoonsub So, Ko Eun Lee, Sang Hyoung Park, Sung-Ae Jung, Joong Haeng Choh, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee
Korean J Intern Med. 2019;34(1):81-89. Published online November 29, 2017
Background/Aims: The Crohn’s and Colitis Knowledge (CCKNOW) score does not reflect updated knowledge relating to inflammatory bowel disease (IBD). The aim of this study was to develop, validate, and apply a novel tool to measure disease-related knowledge in IBD patients.
Methods: A questionnaire ..
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Identification of distinctive clinical significance in hospitalized patients with endoscopic duodenal mucosal lesions
Yeji Han, Hye-Kyung Jung, Ji Young Chang, Chang Mo Moon, Seong-Eun Kim, Ki-Nam Shim, Sung-Ae Jung, Joo-Young Kim, Ji-Yun Bae, Sae-In Kim, Ji-Hyun Lee, Sanghui Park
Korean J Intern Med. 2017;32(5):827-835. Published online August 21, 2017
Background/Aims: Duodenitis is not infrequent finding in patient undergoing endoscopy. However, hospitalized patients have a higher incidence of secondary duodenal mucosal lesions that might be related with inflammatory bowel disease (IBD), cytomegalovirus (CMV) infection, tuberculosis, immunologic ..
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Comparing the clinical outcomes of young-onset and adult-onset ulcerative colitis: a multi-center Korean Association for the Study for Intestinal Diseases study
Ji Yeon Kim, Dong Il Park, Dong Soo Han, Kyu-Chan Huh, Chang Kyun Lee, Jeong Eun Shin, Jae Hak Kim, You Sun Kim, Yunho Jung, Sung-Ae Jung, Hyun Joo Song, Hyun Joo Jang, Young-Ho Kim, Sung No Hong
Korean J Intern Med. 2017;32(1):69-78. Published online June 25, 2016
Background/Aims: The aim of this study was to compare the clinical features and outcomes of ulcerative colitis (UC) according to the age of onset in Korea. Methods: A total of 1,141 patients who were diagnosed with UC between July 1987 and November 2013 at 11 tertiary hospitals were enrolled. The ba..
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Primary Adenosquamous Cell Carcinoma of the Pancreas: A Case Report with a Review of the Korean Literature
Youn Ju Na, Ki-Nam Shim, Min Sun Cho, Sun Hee Sung, Sung-Ae Jung, Kwon Yoo, Kyu Won Chung
Korean J Intern Med. 2011;26(3):348-351. Published online September 13, 2011
The most common pancreatic cancer is adenocarcinoma. Primary adenosquamous cell carcinoma of the pancreas is very rare and aggressive. A 46-year-old man presented with a 3-month history of dyspepsia and a 7-kg weight loss. The physical examination showed tenderness of the right upper quadrant of..
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Infectious Mononucleosis Hepatitis in Young Adults: Two Case Reports
Min-Jung Kang, Tae-Hun Kim, Ki-Nam Shim, Sung-Ae Jung, Min-Sun Cho, Kwon Yoo, Kyu Won Chung
Korean J Intern Med. 2009;24(4):381-387. Published online November 27, 2009
Infectious mononucleosis due to Epstein-Barr virus (EBV) infection sometimes causes acute hepatitis, which is usually self-limiting with mildly elevated transaminases, but rarely with jaundice. Primary EBV infection in children is usually asymptomatic, but in a small number of healthy individuals..
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Antibiotic-Associated Diarrhea: Candidate Organisms other than Clostridium Difficile
Hyun Joo Song, Ki-Nam Shim, Sung-Ae Jung, Hee Jung Choi, Mi Ae Lee, Kum Hei Ryu, Seong-Eun Kim, Kwon Yoo
Korean J Intern Med. 2008;23(1):9-15. Published online March 20, 2008
Backgraound/AimsThe direct toxic effects of antibiotics on the intestine can alter digestive functions and cause pathogenic bacterial overgrowth leading to antibiotic-associated diarrhea (AAD). Clostridium Difficile (C. Difficile) is widely kn..
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A Case of Gastric Tuberculosis Mimicking Advanced Gastric Cancer
Seong-Eun Kim, Ki-Nam Shim, Su Jin Yoon, Sung-Ae Jung, Tae Hun Kim, Kwon Yoo, Il Hwan Moon
Korean J Intern Med. 2006;21(1):62-67. Published online March 30, 2006
Tuberculosis of the stomach is quite rare, both as a primary or secondary infection. It can present as a facet of a multiorgan disease process or may result from immunodeficiency. Here, we report a rare, interesting case of gastric tuberculosis which morphologically mimicked advanced gastric canc..
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