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Rheumatology
Nailfold capillaroscopy findings of interstitial pneumonia with autoimmune features
Sang-Heon Lee, Hong Ki Min, Se-Hee Kim, Young Whan Kim, Kwang Ha Yoo, Hee Joung Kim, In Ae Kim, Hae-Rim Kim
Korean J Intern Med. 2023;38(6):903-911. Published online July 25, 2023
Background/Aims: We evaluated nailfold capillaroscopy (NFC) of interstitial pneumonia with autoimmune features (IPAF) and compared it with that of patients with connective tissue disease-interstitial lung disease (CTD-ILD) and idiopathic interstitial pneumonia (IIP).
Methods: Patients with newly di..
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Tocotrienol regulates osteoclastogenesis in rheumatoid arthritis
Kyoung-Woon Kim, Bo-Mi Kim, Ji-Yeon Won, Hong Ki Min, Seoung Joon Lee, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2021;36(Suppl 1):S273-S282. Published online June 19, 2020
Background/Aims: The present study aimed to investigate whether tocotrienol regulates interleukin 17 (IL-17)-induced osteoclastogenesis in rheumatoid arthritis (RA).
Methods: We evaluated the effect of tocotrienol on IL-17-induced receptor activator of nuclear factor kappa B ligand (RANKL) producti..
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Shingles in palmar cutaneous branch of ulnar nerve
Hong Ki Min, Se Hee Kim, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2021;36(4):1029-1030. Published online April 22, 2020
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Recent advances in the diagnosis and management of interstitial pneumonia with autoimmune features: the perspective of rheumatologists
Hong Ki Min, Se-Hee Kim, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2021;36(3):515-526. Published online February 8, 2021
Interstitial pneumonia with autoimmune feature (IPAF) is a recently established disease entity that is comprised of interstitial lung diseases with evidence of autoimmune features but that does not fulfill the criteria for definite autoimmune rheumatic diseases. The classification criteria for IPAF ..
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Definite visualized communication of a Baker’s cyst with knee joint space and iatrogenic air content in rheumatoid arthritis patient
Hong Ki Min, Se Hee Kim, Sung Gyu Moon, Hae-Rim Kim, Sang-Heon Lee
Korean J Intern Med. 2020;35(5):1254-1255. Published online August 19, 2019
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Rheumatology
Simplified disease activity changes in real-world practice: a nationwide observational study of seropositive rheumatoid arthritis patients with moderate-to-high disease activity
Kichul Shin, Sung Soo Kim, Sang-Heon Lee, Seung-Jae Hong, Sung Jae Choi, Jung-Yoon Choe, Seung-Geun Lee, Hoon-Suk Cha, Eun Young Lee, Sung-Hwan Park, Jin-Wuk Hur, Sung Soo Na, Chang-Hee Suh, Min Wook So, Seung Won Choi, Dong-Hyuk Sheen, Won Park, Shin-Seok Lee, Wan Hee Ryu, Jin Seok Kim, Jung Soo Song, Hye Soon Lee, Seong Ho Kim, Dae-Hyun Yoo
Korean J Intern Med. 2020;35(1):231-239. Published online January 28, 2019
Background/Aims: The objective of this study was to compare changes in the simplified disease activity index (SDAI) between biologic (b) and conventional (c) disease-modifying antirheumatic drugs (DMARD) users with seropositive rheumatoid arthritis (RA) in daily clinical practice. Methods: This was ..
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Roles of mast cells in rheumatoid arthritis
Hong Ki Min, Kyoung-Woon Kim, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2020;35(1):12-24. Published online November 15, 2019
Rheumatoid arthritis (RA) is a chronic autoimmune inflammatory arthritis, and the complex interaction and activation of innate and adaptive immune cells are involved in RA pathogenesis. Mast cells (MCs) are one of the tissue-resident innate immune cells, and they contribute to RA pathogenesis. In th..
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Rheumatology
Magnetic resonance imaging-assessed synovial and bone changes in hand and wrist joints of rheumatoid arthritis patients
Kyung-Ann Lee, Sang-Ho Min, Tae-Hyung Kim, Sang-Heon Lee, Hae-Rim Kim
Korean J Intern Med. 2019;34(3):651-659. Published online November 24, 2017
Background/Aims: Magnetic resonance imaging (MRI) is a sensitive and useful method for the detection of synovitis and joint destruction in rheumatoid arthritis (RA) patients. However, the patterns of MRI-detected bone erosion, bone marrow edema (BME), synovitis, and tenosynovitis have received insuf..
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N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL production in rheumatoid arthritis
Hae-Rim Kim, Kyoung-Woon Kim, Bo-Mi Kim, Kyung-Ann Lee, Sang-Heon Lee
Korean J Intern Med. 2019;34(2):458-458. Published online February 25, 2019
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Rheumatology
N-acetyl-l-cysteine controls osteoclastogenesis through regulating Th17 differentiation and RANKL in rheumatoid arthritis
[corrected-article]
Hae-Rim Kim, Kyoung-Woon Kim, Bo-Mi Kim, Kyung-Ann Lee, Sang-Heon Lee
Korean J Intern Med. 2019;34(1):210-219. Published online March 13, 2017
Background/Aims: This study aimed to determine the regulatory role of N-acetyl-l-cysteine (NAC), an antioxidant, in interleukin 17 (IL-17)-induced osteoclast differentiation in rheumatoid arthritis (RA).
Methods: After RA synovial fibroblasts were stimulated by IL-17, the expression and pro..
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Rapid onset of efficacy predicts response to therapy with certolizumab plus methotrexate in patients with active rheumatoid arthritis
Young Mo Kang, Young-Eun Park, Won Park, Jung-Yoon Choe, Chul-Soo Cho, Seung-Cheol Shim, Sang Cheol Bae, Chang-Hee Suh, Hoon-Suk Cha, Eun Mi Koh, Yeong-Wook Song, Bin Yoo, Shin-Seok Lee, Min-Chan Park, Sang-Heon Lee, Catherine Arendt, Willem Koetse, Soo-Kon Lee
Korean J Intern Med. 2018;33(6):1224-1233. Published online January 5, 2018
Background/Aims: The objective of this study was to determine the efficacy and safety of add-on therapy with certolizumab pegol (CZP) in active rheumatoid arthritis (RA) patients of a single ethnicity.
Methods: In this 24-week, phase 3, randomized, double-blind, placebo-controlled trial, eligible p..
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Impact of early diagnosis on functional disability in rheumatoid arthritis
Dam Kim, Chan-Bum Choi, Jiyoung Lee, Soo-Kyung Cho, Soyoung Won, So-Young Bang, Hoon-Suk Cha, Jung-Yoon Choe, Won Tae Chung, Seung-Jae Hong, Jae-Bum Jun, Young Ok Jung, Jinseok Kim, Seong-Kyu Kim, Tae-Hwan Kim, Tae-Jong Kim, Eunmi Koh, Hye-Soon Lee, Jaejoon Lee, Jisoo Lee, Sang-Heon Lee, Shin-Seok Lee, Sung Won Lee, Seung-Cheol Shim, Dae-Hyun Yoo, Bo Young Yoon, Yoon-Kyoung Sung, Sang-Cheol Bae; KORONA investigators
Korean J Intern Med. 2017;32(4):738-746. Published online September 13, 2016
Background/Aims: To determine whether early diagnosis is beneficial for functional status of various disease durations in rheumatoid arthritis (RA) patients.
Methods: A total of 4,540 RA patients were enrolled as part of the Korean Observational Study Network for Arthritis (KORONA). We defined earl..
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Rhupus syndrome
Jae Ki Min, Kyoung Ann Lee, Hae-Rim Kim, Ho-Youn Kim, Sang-Heon Lee
Korean J Intern Med. 2015;30(1):131-131. Published online December 30, 2014
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Detection of calcium pyrophosphate dihydrate crystal deposition disease by dual-energy computed tomography
Hae-Rim Kim, Jung-Hwa Lee, Na Ra Kim, Sang-Heon Lee
Korean J Intern Med. 2014;29(3):404-405. Published online April 29, 2014
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Induction of Macrophage Migration Inhibitory Factor in ConA-Stimulated Rheumatoid Arthritis Synovial Fibroblasts through the P38 MAP Kinase-Dependent Signaling Pathway
Hae-Rim Kim, Mi-Kyung Park, Mi-La Cho, Kyoung-Woon Kim, Hye-Joa Oh, Jin-Sil Park, Yang-Mi Heo, Sang-Heon Lee, Ho-Youn Kim, Sung-Hwan Park
Korean J Intern Med. 2010;25(3):317-326. Published online August 31, 2010
Background/AimsThis study was undertaken to identify the intracellular signaling pathway involved in induction of macrophage migration inhibitory factor (MIF) in human rheumatoid arthritis (RA) synovial fibroblasts. MethodsHuman RA synovial fibr..
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