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Hemato-oncology / Original Article
Reduced-intensity chemotherapy with tyrosine kinase inhibitor followed by allogeneic transplantation is effective in patients with Philadelphia chromosome-positive acute lymphoblastic leukemia
Jung Min Lee, Do Young Kim, Hee Jeong Cho, Joon Ho Moon, Sang Kyun Sohn, Ho Jin Shin, Young Rok Do, Mi Hwa Heo, Min Kyoung Kim, Young Seob Park, Dong Won Baek
Korean J Intern Med. 2025;40(1):124-134. Published online January 1, 2025
Background/Aims: To determine the effectiveness of tyrosine kinase inhibitor (TKI) plus reduced-intensity therapy in adult patients with newly diagnosed Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph-positive ALL), this retrospective study compared treatment outcomes and induction..
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Hemato-oncology / Original Article
Rituximab plus multiagent chemotherapy for newly diagnosed CD20-positive acute lymphoblastic leukemia: a prospective phase II study
Dong Won Baek, Han-Seung Park, Sang Kyun Sohn, Dae Young Kim, Inho Kim, Jae-Sook Ahn, Young Rok Do, Se Ryeon Lee, Hyeon-Seok Eom, Won-Sik Lee, Sung-Hyun Kim, Ho Sup Lee, Yoo Jin Lee, Joon Ho Moon, Je-Hwan Lee; Adult Acute Lymphoblastic Leukemia Working Party, the Korean Society of Hematology
Korean J Intern Med. 2023;38(5):734-746. Published online June 20, 2023
Background/Aims: We performed a prospective study to determine the efficacy and safety of rituximab including chemotherapy in CD20-positive acute lymphoblastic leukemia (ALL).
Methods: Patients with newly diagnosed ALL, aged ≥ 15 years, were eligible for the study if their leukemic blast cells in ..
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Hemato-oncology / Original Article
Pediatric-inspired regimen with late intensification and increased dose of L-asparaginase for adult acute lymphoblastic leukemia: the KALLA 1406/1407 study
Dong Won Baek, Dae Young Kim, Sang Kyun Sohn, Youngil Koh, Sung-Hoon Jung, Ho-Young Yhim, Yunsuk Choi, Joon Ho Moon
Korean J Intern Med. 2021;36(6):1471-1485. Published online September 24, 2021
Background/Aims: The objective of this study was to evaluate the efficacy and feasibility of the pediatric-inspired regimen of the adult acute lymphoblastic leukemia (ALL) Working Party, the Korean Society of Hematology.
Methods: Data of 99 patients with newly diagnosed ALL, who were treated with t..
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Hemato-oncology / Original Article
No benefit of hypomethylating agents compared to supportive care for higher risk myelodysplastic syndrome
Sang Kyun Sohn, Joon Ho Moon, In Hee Lee, Jae Sook Ahn, Hyeoung Joon Kim, Joo Seop Chung, Ho Jin Shin, Sung Woo Park, Won Sik Lee, Sang Min Lee, Hawk Kim, Ho Sup Lee, Yang Soo Kim, Yoon Young Cho, Sung Hwa Bae, Ji Hyun Lee, Sung Hyun Kim, Ik Chan Song, Ji Hyun Kwon, Yoo Jin Lee
Korean J Intern Med. 2018;33(6):1194-1202. Published online December 15, 2017
Background/Aims: This study evaluated the role of hypomethylating agents (HMA) compared to best supportive care (BSC) for patients with high or very-high (H/VH) risk myelodysplastic syndrome (MDS) according to the Revised International Prognostic Scoring System.
Methods: A total of 279 H/VH risk MD..
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Letter to the editor
New synergistic efficacy of combination of romiplostim and steroid in refractory immune thrombocytopenia patients
Jun Seok Yoon, Yoo Jin Lee, Dong Won Baek, Hye Young Park, Bo Eun Park, Joon Ho Moon, Sang Kyun Sohn
Korean J Intern Med. 2018;33(2):435-437. Published online March 7, 2016
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Letter to the editor
First Korean case of Emberger syndrome (primary lymphedema with myelodysplasia) with a novel GATA2 gene mutation
Sang Kyung Seo, Kyu Yeun Kim, Seo Ae Han, Joon Seok Yoon, Sang-Yong Shin, Sang Kyun Sohn, Joon Ho Moon
Korean J Intern Med. 2016;31(1):188-190. Published online December 28, 2015
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Hemato-oncology / Original Article
Clinical significance of nuclear factor κB and chemokine receptor CXCR4 expression in patients with diffuse large B-cell lymphoma who received rituximab-based therapy
Ho Cheol Shin, Jongwon Seo, Byung Woog Kang, Joon Ho Moon, Yee Soo Chae, Soo Jung Lee, Yoo Jin Lee, Seoae Han, Sang Kyung Seo, Jong Gwang Kim, Sang Kyun Sohn, Tae-In Park
Korean J Intern Med. 2014;29(6):785-792. Published online October 31, 2014
Background/Aims: This study investigated the expression of nuclear factor κB (NF-κB) and the chemokine receptor (CXCR4) in patients with diffuse large B-cell lymphoma (DLBCL) who received rituximab-based therapy.
Methods: Seventy patients with DLBCL and treated with rituximab-CHOP (R-CHO..
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Original Article
Feasibility of Non-TBI Conditioning with Busulfan and Fludarabine for Allogeneic Stem Cell Transplantation in Lymphoid Malignancy
Ho Cheol Shin, Yoo Jin Lee, Joon Ho Joon Ho, Soo Jung Lee, Byung Woog Kang, Yee Soo Chae, Jong Gwang Kim, Jun Young Choi, Jong Won Seo, Yu Kyung Kim, Jang Soo Suh, Sang Kyun Sohn
Korean J Intern Med. 2012;27(1):72-83. Published online February 28, 2012
Background/AimsThis retrospective study evaluated the transplantation outcomes of patients with adult lymphoid malignancies who received chemotherapy-based conditioning with busulfan and fludarabine (BuFlu) and busulfan and cyclophosphamide (BuCy2). Method.. </div>
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<td style="padding-left:10px;padding-right:27px; padding-top:10px;padding-bottom:10px;width:733px;" valign="top" >
<div style="color:#C62F37;font-family:'Noto Sans KR', 'Nanum Gothic', sans-serif;">Case Report </div>
<a class="artiletitle" href="/journal/view.php?number=15679" onmouseover="showAbstract('15679' );" onmouseout="hideAbstract('15679' );"><b><font>Unpredicted Severe Toxicity after 5-Fluorouracil Treatment due to Dihydropyrimidine Dehydrogenase Deficiency</font></b></a>
<div style="padding-top:2px;padding-left:0px" class="article_authors">Jin Ho Baek, Jong Gwang Kim, Shi Nae Kim, Dong Hwan Kim, Sang Kyun Sohn, Young Jun Hong, Kyu Bo Lee</div>
<div style="padding-top:2px;padding-left:0px" class="article_issue">
<em>Korean J Intern Med.</em> 2006;21(1):43-45. Published online March 30, 2006 </div>
<div class="doi">DOI: <a href="https://doi.org/10.3904/kjim.2006.21.1.43"><font class="doi">https://doi.org/10.3904/kjim.2006.21.1.43</font></a>
<a href="/journal/CitedByRenew.php?number=15679" onclick="window.open(this.href, 'CrossRef Citedby', 'width=800,height=800,scrollbars=yes');return false;" style="color:#DD434F;font-size:10pt;"> Crossref 10</a>
</div>
<div class="etc" style="padding-top:5px;text-align: right;">
<a href='/journal/view.php?number=15679' style='text-decoration:underline;color:#2046f8'><img src='/image/button/fulltext.gif' alt='Full Text' /></a> <a href='/journal/view.php?viewtype=pubreader&number=15679' style='text-decoration:underline;color:#2046f8'><img src='/image/button/pubreader.gif' alt='PubReader' /></a> <a style='cursor: pointer;' onclick='journal_download("epub", "15679", "path=L2hvbWUvdmlydHVhbC9rYWltL2pvdXJuYWwvdXBsb2FkL2VwdWIva2ppbS0yMS00My5lcHVi&filename=a2ppbS0yMS00My5lcHVi")'><img src='/image/button/epub.gif' alt='ePub' /></a> <a style='cursor: pointer;' onclick='journal_download("pdf", "15679", "kjim-21-43.pdf")'><img src='/image/button/pdf.gif' alt='PDF' /></a> </div>
<div id="15679" style="display:none;padding-top:10px;padding-left:0px; color:#7b7b7b">
<p>Dihydropyrimidine dehydrogenase (DPD) is the initial and rate-limiting enzyme in the catabolism of 5-fluorouracil (5-FU). Thus, patients with a DPD deficiency are at risk of developing severe 5-FU-associated toxicity.</p><p>A 37-year-old female with gastric cancer underwent a curative operation, .. </div>
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<div style="color:#C62F37;font-family:'Noto Sans KR', 'Nanum Gothic', sans-serif;">Case Report </div>
<a class="artiletitle" href="/journal/view.php?number=15613" onmouseover="showAbstract('15613' );" onmouseout="hideAbstract('15613' );"><b><font>Malignant Peripheral Nerve Sheath Tumor in Neurofibromatosis Type I : Unusual Presentation of Intraabdominal or Intrathoracic Mass</font></b></a>
<div style="padding-top:2px;padding-left:0px" class="article_authors">Jong Gwang Kim, Woo Jin Sung, Dong Hwan Kim, Young Hwan Kim, Sang Kyun Sohn, Kyu Bo Lee</div>
<div style="padding-top:2px;padding-left:0px" class="article_issue">
<em>Korean J Intern Med.</em> 2005;20(1):100-104. Published online March 31, 2005 </div>
<div class="doi">DOI: <a href="https://doi.org/10.3904/kjim.2005.20.1.100"><font class="doi">https://doi.org/10.3904/kjim.2005.20.1.100</font></a>
<a href="/journal/CitedByRenew.php?number=15613" onclick="window.open(this.href, 'CrossRef Citedby', 'width=800,height=800,scrollbars=yes');return false;" style="color:#DD434F;font-size:10pt;"> Crossref 6</a>
</div>
<div class="etc" style="padding-top:5px;text-align: right;">
<a href='/journal/view.php?number=15613' style='text-decoration:underline;color:#2046f8'><img src='/image/button/fulltext.gif' alt='Full Text' /></a> <a href='/journal/view.php?viewtype=pubreader&number=15613' style='text-decoration:underline;color:#2046f8'><img src='/image/button/pubreader.gif' alt='PubReader' /></a> <a style='cursor: pointer;' onclick='journal_download("epub", "15613", "path=L2hvbWUvdmlydHVhbC9rYWltL2pvdXJuYWwvdXBsb2FkL2VwdWIva2ppbS0yMC0xMDAuZXB1Yg==&filename=a2ppbS0yMC0xMDAuZXB1Yg==")'><img src='/image/button/epub.gif' alt='ePub' /></a> <a style='cursor: pointer;' onclick='journal_download("pdf", "15613", "kjim-20-100.pdf")'><img src='/image/button/pdf.gif' alt='PDF' /></a> </div>
<div id="15613" style="display:none;padding-top:10px;padding-left:0px; color:#7b7b7b">
<p>A malignant peripheral nerve sheath tumor (MPNST) is an extremely rare soft tissue tumor in the general population. On the other hand, there is a higher incidence of MPNST in patients with neurofibromatosis type I (von Recklinghausen's disease). The common sites are the extremities, trunk, head a.. </div>
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<div style="color:#C62F37;font-family:'Noto Sans KR', 'Nanum Gothic', sans-serif;">Case Report </div>
<a class="artiletitle" href="/journal/view.php?number=7922" onmouseover="showAbstract('7922' );" onmouseout="hideAbstract('7922' );"><b><font>Pancytopenic Prodrome pre - ALL of Acute Lymphoblastic Leukemia in Adults ; Possible Pathogenesis</font></b></a>
<div style="padding-top:2px;padding-left:0px" class="article_authors">Sang Kyun Sohn, Jang Soo Suh, Jae Tae Lee, Kyu Bo Lee</div>
<div style="padding-top:2px;padding-left:0px" class="article_issue">
<em>Korean J Intern Med.</em> 1998;13(1):64-67. Published online February 1, 1998 </div>
<div class="doi">DOI: <a href="https://doi.org/10.3904/kjim.1998.13.1.64"><font class="doi">https://doi.org/10.3904/kjim.1998.13.1.64</font></a>
<a href="/journal/CitedByRenew.php?number=7922" onclick="window.open(this.href, 'CrossRef Citedby', 'width=800,height=800,scrollbars=yes');return false;" style="color:#DD434F;font-size:10pt;"> Crossref 3</a>
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<div class="etc" style="padding-top:5px;text-align: right;">
<a href='/journal/view.php?number=7922' style='text-decoration:underline;color:#2046f8'><img src='/image/button/fulltext.gif' alt='Full Text' /></a> <a href='/journal/view.php?viewtype=pubreader&number=7922' style='text-decoration:underline;color:#2046f8'><img src='/image/button/pubreader.gif' alt='PubReader' /></a> <a style='cursor: pointer;' onclick='journal_download("epub", "7922", "path=L2hvbWUvdmlydHVhbC9rYWltL2pvdXJuYWwvdXBsb2FkL2VwdWIva2ppbS0xMy0xLTY0LTEyLmVwdWI=&filename=a2ppbS0xMy0xLTY0LTEyLmVwdWI=")'><img src='/image/button/epub.gif' alt='ePub' /></a> <a style='cursor: pointer;' onclick='journal_download("pdf", "7922", "kjim-13-1-64-12.pdf")'><img src='/image/button/pdf.gif' alt='PDF' /></a> </div>
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<p style='font-size:1.3em;font-weight:bold;color:#C62F37;padding-bottom:10px;'>Korean Journal of<br/>Internal Medicine</p>
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Print ISSN: 1226-3303<br/>
Online ISSN: 2005-6648<br/>
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