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Machine learning approaches toward an understanding of acute kidney injury: current trends and future directions
Inyong Jeong, Nam-Jun Cho, Se-Jin Ahn, Hwamin Lee, Hyo-Wook Gil
Korean J Intern Med. 2024;39(6):882-897. Published online October 29, 2024
Acute kidney injury (AKI) is a significant health challenge associated with adverse patient outcomes and substantial economic burdens. Many authors have sought to prevent and predict AKI. Here, we comprehensively review recent advances in the use of artificial intelligence (AI) to predict AKI, and t..
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Emotional and cognitive changes in chronic kidney disease
Duk-Soo Kim, Seong-Wook Kim, Hyo-Wook Gil
Korean J Intern Med. 2022;37(3):489-501. Published online March 8, 2022
Chronic kidney disease (CKD) leads to cognitive impairment and emotional changes. However, the precise mechanism underlying the crosstalk between the kidneys and the nervous system is not fully understood. Inflammation and cerebrovascular disease can influence the development of depression in CKD. C..
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Nephrology
The effects of nonyl phenoxypolyethoxyl ethanol on cell damage pathway gene expression in SK-NSH cells
Samel Park, Il-woong Hwang, Jin-sheon Kim, Hyo-chul Kang, Su-Yeon Park, Hyo-wook Gil, Ho-yeon Song, Sae-yong Hong
Korean J Intern Med. 2015;30(6):873-883. Published online October 30, 2015
Background/Aims: Most pesticide formulations contain both chief and additive ingredients. But, the additives may not have been tested as thoroughly as the chief ingredients. The surfactant, nonyl phenoxypolyethoxylethanol (NP40), is an additive frequently present in pesticide formulations. We invest..
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The dose of cyclophosphamide for treating paraquat-induced rat lung injury
Jae-Sung Choi, Sung-Shick Jou, Mee-Hye Oh, Young-Hee Kim, Min-Ju Park, Hyo-Wook Gil, Ho-Yeon Song, Sae-Yong Hong
Korean J Intern Med. 2013;28(4):420-427. Published online July 1, 2013
Background/AimsCyclophosphamide (CP) is a promising treatment for severe cases of paraquat (PQ) poisoning. We investigated the effective dose of CP for mitigating PQ-induced lung injury. MethodsAdult male Sprague-Dawley rats were allocated into ..
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Erratum: A Case of Green Urine after Ingestion of Herbicides
Yun-Suk Shim, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Soo-Hyun Kim, Sae-Yong Hong
Korean J Intern Med. 2012;27(4):483-483. Published online November 27, 2012
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Association of the Superoxide Dismutase (V16A) and Catalase (C262T) Genetic Polymorphisms with the Clinical Outcome of Patients with Acute Paraquat Intoxication
Joong-Rock Hong, Su-Jin Seok, Du-Shin Jeong, Sang-Gon Lee, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2010;25(4):422-428. Published online November 27, 2010
Background/AimsMany patients with acute paraquat (PQ) intoxication die even at low PQ concentrations, whereas others with similar concentrations recover. Therefore, it is possible that individual differences in antioxidant capacity are responsible for the variable clinical out..
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Effect of Glutathione Administration on Serum Levels of Reactive Oxygen Metabolites in Patients with Paraquat Intoxication: A Pilot Study
Jung-Hoon Kim, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2010;25(3):282-287. Published online August 31, 2010
Background/AimsBased on preliminary in vitro data from a previous study, we proposed that 50 mg/kg glutathione (GSH) would be adequate for suppressing reactive oxygen species in patients with acute paraquat (PQ) intoxication. Methods</titl.. </div>
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<a class="artiletitle" href="/journal/view.php?number=162363" onmouseover="showAbstract('162363' );" onmouseout="hideAbstract('162363' );"><b><font>Factors for Determining Survival in Acute Organophosphate Poisoning</font></b></a>
<div style="padding-top:2px;padding-left:0px" class="article_authors">Eun-Jung Kang, Su-Jin Seok, Kwon-Hyun Lee, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong</div>
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<em>Korean J Intern Med.</em> 2009;24(4):362-367. Published online November 27, 2009 </div>
<div class="doi">DOI: <a href="https://doi.org/10.3904/kjim.2009.24.4.362"><font class="doi">https://doi.org/10.3904/kjim.2009.24.4.362</font></a>
<a href="/journal/CitedByRenew.php?number=162363" onclick="window.open(this.href, 'CrossRef Citedby', 'width=800,height=800,scrollbars=yes');return false;" style="color:#DD434F;font-size:10pt;"> Crossref 38</a>
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<a href='/journal/view.php?number=162363' style='text-decoration:underline;color:#2046f8'><img src='/image/button/fulltext.gif' alt='Full Text' /></a> <a href='/journal/view.php?viewtype=pubreader&number=162363' style='text-decoration:underline;color:#2046f8'><img src='/image/button/pubreader.gif' alt='PubReader' /></a> <a style='cursor: pointer;' onclick='journal_download("epub", "162363", "path=L2hvbWUvdmlydHVhbC9rYWltL2pvdXJuYWwvdXBsb2FkL2VwdWIva2ppbS0yNC0zNjIuZXB1Yg==&filename=a2ppbS0yNC0zNjIuZXB1Yg==")'><img src='/image/button/epub.gif' alt='ePub' /></a> <a style='cursor: pointer;' onclick='journal_download("pdf", "162363", "kjim-24-362.pdf")'><img src='/image/button/pdf.gif' alt='PDF' /></a> </div>
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<sec><title>Background/AimsOrganophosphate poisoning has a high mortality rate. Recently, differences among organophosphorus insecticides in human self-poisoning were reported. This study investigated the prognostic risk factors and the mortality of different organophosphates following ac..
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Paraquat Intoxication in Subjects Who Attempt Suicide: Why They Chose Paraquat
Su-Jin Seok, Hyo-Wook Gil, Du-Shin Jeong, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2009;24(3):247-251. Published online August 26, 2009
Background/AimsParaquat (PQ) has been used in suicide attempts; an estimated 2,000 toxic ingestions occur annually, with 60-70% mortality. We sought to determine why PQ is such a common agent for suicide attempts in Korea. MethodsWe analyzed 250..
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Marked Recovery From Paraquat-Induced Lung Injury During Long-Term Follow-up
Kwon-Hyun Lee, Hyo-Wook GIL, Young-Tong Kim, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2009;24(2):95-100. Published online June 8, 2009
Background/AimsParaquat-induced lung injury has been considered a progressive and irreversible disease. The purpose of this study was to report the long-term evolution of lung lesions in eight survivors with significant paraquat-induced lung injuries who could be followed-up f..
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Benzene and toluene concentrations in a hemodialysis room in a medium sized South Korean city
Moon-Soo Kang, Joong-Rock Hong, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong, Yong-Taek Jun, Bu-Soon Son
Korean J Intern Med. 2008;23(3):111-115. Published online September 20, 2008
Background/AimsThe current study was designed to determine whether the indoor air pollution in a hemodialysis room (HD) was different from that of other comparable areas in a hospital. MethodsFive air monitor samplers were hun..
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A Case of Green Urine after Ingestion of Herbicides
Yun-Suk Shim, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Soo-Hyun Kim, Sae-Yong Hong
Korean J Intern Med. 2008;23(1):42-44. Published online March 20, 2008
The development of discolored urine may have many possible causes. Here we present the case of a 76-year-old woman who was admitted after ingesting the inorganic herbicides, mefenacet and imazosulfuron. Her urine color changed to green almost immediately. Since the patient had no specific medicat..
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Relationship between Pulmonary Surfactant Protein and Lipid Peroxidation in Lung Injury due to Paraquat Intoxication in Rats
Hyo-Wook Gil, Mi-Hae Oh, Kee-Min Woo, Eun-Young Lee, Myung-Ho Oh, Sae-Yong Hong
Korean J Intern Med. 2007;22(2):67-72. Published online June 30, 2007
BackgroundPulmonary damage resulting from lipid peroxidation is a principal effect of paraquat intoxication. The host-defense functions of surfactant are known to be mediated by the surfactant proteins A and D (SP-A and SP-D, respectively). The primary objective of this study ..
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Effect of High-Dose Intravenous N-acetylcysteine on the Concentration of Plasma Sulfur-Containing Amino Acids
Sae-Yong Hong, Hyo-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Hyung-Kee Kim, Soo-Hyun Kim, Young-Ho Chung, Eun-Mi Lee, Soo-Kyung Hwang
Korean J Intern Med. 2005;20(3):217-223. Published online September 30, 2005
BackgroundThe purpose of this study was to determine the adequate loading and maintenance doses of N-acetylcyseteine (NAC) for patients suffering from acute ROS-induced injury. MethodsConcentrations of extra cellular NAC, cysteine (Cys), cystine..
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