Phosphodiesterase Inhibitor Improves Renal Tubulointerstitial Hypoxia of the Diabetic Rat Kidney
Hui-Kyoung Sun, Yun Mi Lee, Kum Hyun Han, Han-Seong Kim, Seon-Ho Ahn, Sang-Youb Han
Korean J Intern Med. 2012;27(2):163-170. Published online May 31, 2012
Background/AimsRenal hypoxia is involved in the pathogenesis of diabetic nephropathy. Pentoxifyllin (PTX), a nonselective phosphodiesterase inhibitor, is used to attenuate peripheral vascular diseases. To determine whether PTX can improve renal hypoxia, we investigated its eff..
|