| Reviews |
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Gastroenterology
Recent trends in diagnostic techniques for inflammatory bowel disease
Makoto Naganuma, Naoki Hosoe, Takanori Kanai, Haruhiko Ogata
Korean J Intern Med. 2015;30(3):271-278. Published online April 29, 2015
Although ileocolonoscopy is the gold standard for diagnosis of inflammatory bowel disease and is useful for assessing the disease severity in the colon and terminal ileum, several alternative diagnostic techniques have been developed recently. For ulcerative colitis (UC), magnification colonoscopy, ..
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Biomedical Engineering
Hard tissue regeneration using bone substitutes: an update on innovations in materials
Swapan Kumar Sarkar, Byong Taek Lee
Korean J Intern Med. 2015;30(3):279-293. Published online April 29, 2015
Bone is a unique organ composed of mineralized hard tissue, unlike any other body part. The unique manner in which bone can constantly undergo self-remodeling has created interesting clinical approaches to the healing of damaged bone. Healing of large bone defects is achieved using implant materials..
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Microbiology
Clinical implications of copy number variations in autoimmune disorders
Seon-Hee Yim, Seung-Hyun Jung, Boram Chung, Yeun-Jun Chung
Korean J Intern Med. 2015;30(3):294-304. Published online April 29, 2015
Human genetic variation is represented by the genetic differences both within and among populations, and most genetic variants do not cause overt diseases but contribute to disease susceptibility and influence drug response. During the last century, various genetic variants, such as copy number var..
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| Editorial |
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| Original Articles |
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Gastroenterology
Use of 18F-FDG PET to predict tumor progression and survival in patients with intermediate hepatocellular carcinoma treated by transarterial chemoembolization
Min Jin Kim, Young Seok Kim, Youn Hee Cho, Hee Yoon Jang, Jeong-Yeop Song, Sae Hwan Lee, Soung Won Jeong, Sang Gyune Kim, Jae Young Jang, Hong Su Kim, Boo Sung Kim, Won Hyung Lee, Jung Mi Park, Jae Myung Lee, Min Hee Lee, Deuk Lin Choi
Korean J Intern Med. 2015;30(3):308-315. Published online April 29, 2015
Background/Aims: 18F-Fluorodeoxyglucose positron-emission tomography (18F-FDG PET) has been used to assess the biological behavior of hepatocellular carcinoma (HCC). In this study, we investigated the usefulness of 18F-FDG PET for predicting tumor progression and sur..
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Cardiology
The relationship between serum asymmetric dimethylarginine levels and subjective sleep quality in normotensive patients with type 2 diabetes mellitus
Alpay Aribas, Mehmet Kayrak, Mehmet Tekinalp, Hakan Akilli, Hayrudin Alibasic, Serkan Yildirim, Mehmet Gunduz, Alpaslan Taner, Ali Unlu
Korean J Intern Med. 2015;30(3):316-324. Published online April 29, 2015
Background/Aims: Poor sleep quality (SQ) is associated with increased cardiovascular mortality and morbidity. Additionally, asymmetric dimethylarginine (ADMA) is an independent predictor of cardiovascular mortality and morbidity. However, no sufficient data regarding the relationship between ADMA le..
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Pulmonology
Drug-resistance pattern of Mycobacterium tuberculosis strains from patients with pulmonary and extrapulmonary tuberculosis during 2006 to 2013 in a Korean tertiary medical center
Ho Young Lee, Jin Lee, Young Seok Lee, Mi-Yeong Kim, Hyun-Kyung Lee, Young-Min Lee, Jeong Hwan Shin, Yousang Ko
Korean J Intern Med. 2015;30(3):325-334. Published online April 29, 2015
Background/Aims: We evaluated the trend in the rates of drug-resistant tuberculosis (TB) over time, as well as the difference in the drug-resistance pattern between pulmonary tuberculosis (PTB) and extrapulmonary tuberculosis (EPTB) at a private referral center in South Korea.
Methods: All patients..
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Endocrinology-metabolism
Reference interval for thyrotropin in a ultrasonography screened Korean population
Mijin Kim, Tae Yong Kim, Soo Han Kim, Yunkyoung Lee, Su-yeon Park, Hyung-Don Kim, Hyemi Kwon, Yun Mi Choi, Eun Kyung Jang, Min Ji Jeon, Won Gu Kim, Young Kee Shong, Won Bae Kim
Korean J Intern Med. 2015;30(3):335-344. Published online April 29, 2015
Background/Aims: The diagnostic accuracy of thyroid dysfunctions is primarily affected by the validity of the reference interval for serum thyroid-stimulating hormone (TSH). Thus, the present study aimed to establish a reference interval for TSH using a normal Korean population.
Methods: This study..
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Nephrology
Plasma neutrophil gelatinase-associated lipocalin as a potential predictor of adverse renal outcomes in immunoglobulin A nephropathy
Ga-Young Park, Chung-Hoon Yu, Jun-Seop Kim, Yun-Jeong Kang, Owen Kwon, Ji-Young Choi, Jang-Hee Cho, Chan-Duck Kim, Yong-Lim Kim, Sun-Hee Park
Korean J Intern Med. 2015;30(3):345-353. Published online April 29, 2015
Background/Aims: Neutrophil gelatinase-associated lipocalin (NGAL) is a well-known biomarker of acute kidney injury. We evaluated the value of plasma NGAL (pNGAL) as an independent predictor of prognosis in immunoglobulin A nephropathy (IgAN).
Methods: In total, 91 patients with biopsy-proven IgAN ..
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High serum and urine neutrophil gelatinase-associated lipocalin levels are independent predictors of renal progression in patients with immunoglobulin A nephropathy
Harin Rhee, Nari Shin, Min Ji Shin, Byung Yun Yang, Il Young Kim, Sang Heon Song, Dong Won Lee, Soo Bong Lee, Ihm Soo Kwak, Eun Young Seong
Korean J Intern Med. 2015;30(3):354-361. Published online April 29, 2015
Background/Aims: Tubulointerstitial injury plays an important role in the progression of immunoglobulin A nephropathy (IgAN), and neutrophil gelatinase-associated lipocalin (NGAL) is among the most sensitive tubular biomarkers. We investigated whether serum or urine NGAL predicts prognosis in patien..
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Hemato-oncology
Role of frontline autologous stem cell transplantation in young, high-risk diffuse large B-cell lymphoma patients
Jae-Ho Yoon, Jong-Wook Kim, Young-Woo Jeon, Sung-Eun Lee, Ki-Seong Eom, Yoo-Jin Kim, Seok Lee, Hee-Je Kim, Chang-Ki Min, Jong-Wook Lee, Woo-Sung Min, Chong-Won Park, Seok-Goo Cho
Korean J Intern Med. 2015;30(3):362-371. Published online April 29, 2015
Background/Aims: Several studies have demonstrated the effect of autologous hematopoietic stem cell transplantation (auto-HSCT) as a salvage treatment for patients with relapsed diffuse large B-cell lymphoma (DLBCL). However, the role of auto-HSCT as a frontline treatment has not been fully investig..
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Infectious diseases
A comparison of the clinical characteristics of elderly and non-elderly women with community-onset, non-obstructive acute pyelonephritis
U-Im Chang, Hyung Wook Kim, Yong-sun Noh, Seong-Heon Wie
Korean J Intern Med. 2015;30(3):372-383. Published online April 29, 2015
Background/Aims: Acute pyelonephritis (APN) is the most common cause of community-onset bacteremia in hospitalized elderly patients. The objectives of this study were to investigate the differences in the clinical and microbiological data of hospitalized elderly and non-elderly women with community-..
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Rheumatology
Sleep quality in rheumatoid arthritis, and its association with disease activity in a Korean population
Chang-Nam Son, Go Choi, So-Yeon Lee, Ji-Min Lee, Tae-Han Lee, Hye-Jin Jeong, Chang-Gyu Jung, Ji-Min Kim, Yong-Won Cho, Sang-Hyon Kim
Korean J Intern Med. 2015;30(3):384-390. Published online April 29, 2015
Background/Aims: The aim of this study was to compare the sleep quality between rheumatoid arthritis (RA) patients and healthy controls; and to evaluate the relationship between RA disease activity and sleep quality in Korea.
Methods: A total of 130 RA patients and 67 age- and sex-matched healthy c..
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Predictive factors of radiographic progression in ankylosing spondylitis
Hyungjin Kim, Jaejoon Lee, Joong Kyong Ahn, Jiwon Hwang, Eun-Jung Park, Hyemin Jeong, Hoon-Suk Cha, Eun-Mi Koh
Korean J Intern Med. 2015;30(3):391-397. Published online April 29, 2015
Background/Aims: The course of ankylosing spondylitis (AS) is rather variable, and the factors that predict radiographic progression remain largely obscure. In this study, we tried to determine the clinical factors and laboratory measures that are useful in predicting the radiographic progression of..
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| Letters to the editor |
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Gastroenterology
Pancreatic mucinous cystadenoma of borderline malignancy associated with Clonorchis sinensis
Jong Hwan Choi, Ji Hoon Kim, Chung Ho Kim, Young Kul Jung, Jong Eun Yeon, Kwan Soo Byun, Insun Kim
Korean J Intern Med. 2015;30(3):398-401. Published online April 29, 2015
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Nephrology
Cutaneous vasculitis and renal involvement in Mycoplasma pneumoniae infection
Hajeong Lee, Kyung Chul Moon, Suhnggwon Kim
Korean J Intern Med. 2015;30(3):402-405. Published online April 29, 2015
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Henoch-Schönlein purpura secondary to infective endocarditis in a patient with pulmonary valve stenosis and a ventricular septal defect
Sung Eun Ha, Tae Hyun Ban, Sung Min Jung, Kang Nam Bae, Byung Ha Chung, Cheol Whee Park, Bum-Soon Choi
Korean J Intern Med. 2015;30(3):406-410. Published online April 29, 2015
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Hemato-oncology
Triple-negative breast cancer that progressed as estrogen receptor-positive skin metastases
Sang Min Lee, Eun Jin Kang, Ju Hee Kim, Jong Min Yun, Der Sheng Sun, Yoon Ho Ko, Hye Sung Won
Korean J Intern Med. 2015;30(3):411-414. Published online April 29, 2015
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Rheumatology
Polymyalgia rheumatica following paraspinal muscle inflammation and sacroiliitis
Taeseok Lim, Seokyung Woo, Yoon Gwon Mun, Eunjung Yim, Jung Hee Koh, Kyung-Su Park
Korean J Intern Med. 2015;30(3):415-417. Published online April 29, 2015
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| Images of interest |
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Homonymous hemianopia in a patient with Behcet’s disease
Won-Seok Lee, Mi-Hee Kang, Won-Sik Jung, Yun-Hong Cheon, Wan-Hee Yoo
Korean J Intern Med. 2015;30(3):418-419. Published online April 29, 2015
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| Erratum |
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Intrathoracic kidney with left-sided Bochdalek hernia in a woman with bacteremic acute pyelonephritis due to Escherichia coli
Yong-sun Noh, Yeonguk Kim, Yun Seo, Seong-Heon Wie, U-Im Chang
Korean J Intern Med. 2015;30(3):421-421. Published online April 29, 2015
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