Review |
Molecular Mechanism of Insulin Resistance in Obesity and Type 2 Diabetes
Kangduk Choi, Young-Bum Kim
Korean J Intern Med. 2010;25(2):119-129. Published online June 1, 2010
Insulin resistance is a major risk factor for developing type 2 diabetes caused by the inability of insulin-target tissues to respond properly to insulin, and contributes to the morbidity of obesity. Insulin action involves a series of signaling cascades initiated by insulin binding to its recept..
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Editorial |
Smoking Rather than Diet Deficiency is Related with Airway Obstruction in Korea
Hojoong Kim
Korean J Intern Med. 2010;25(2):130-131. Published online June 1, 2010
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Original Articles |
Diet and Airway Obstruction: A Cross Sectional Study from the Second Korean National Health and Nutrition Examination Survey
Jin Hwa Lee, Yun Su Sim, Gee Young Suh, Jeong-Seon Ryu, Dong Ho Shin, Kyung Haeng Koh, Yeon Jae Kim, Wan Park, Hyoung Kyu Yoon, Man Jae Lee, Jung Hyun Chang,
Korean J Intern Med. 2010;25(2):132-139. Published online June 1, 2010
Background/AimsSeveral dietary factors, such as antioxidant vitamins, have potential roles in the development of obstructive lung diseases. However, the results of studies on the relationships between dietary factors and obstructive lung diseases are inconsistent. The aim of t..
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Clinical Characteristics of Colonic Diverticulosis in Korea: A Prospective Study
Jung Hoon Song, You Sun Kim, Jin Ho Lee, Kyung Sun Ok, Soo Hyung Ryu, Jung Hwan Lee, Jeong Seop Moon
Korean J Intern Med. 2010;25(2):140-146. Published online June 1, 2010
Background/AimsThe prevalence of colonic diverticulosis has been reported to be lower in Korea than in Western countries. This disease also shows markedly different characteristics in the Korean population. We describe herein a prospective investigation, based on colonoscopic ..
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Characteristics of Double-Chambered Right Ventricle in Adult Patients
Yu Jeong Choi, Seung Woo Park
Korean J Intern Med. 2010;25(2):147-153. Published online June 1, 2010
Background/AimsThis study evaluated the clinical features of double-chambered right ventricle (DCRV) in adults. Most cases of DCRV are diagnosed and treated during childhood. Consequently, very few reports include cases in which its clinical characteristics are evident in adul..
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The Impact of Generic Clopidogrel Bisulfate on Platelet Inhibition in Patients with Coronary Artery Stents: Results of the ACCEL-GENERIC Study
Young-Hoon Jeong, Jin-Sin Koh, Min-Kyung Kang, Yeon-Jeong Ahn, In-Suk Kim, Yongwhi Park, Seok-Jae Hwang, Choong Hwan Kwak, Jin-Yong Hwang
Korean J Intern Med. 2010;25(2):154-161. Published online June 1, 2010
Background/AimsIn patients with coronary artery stents, the cost of clopidogrel has been cited as a factor in the premature discontinuation of therapy. Thus, the introduction of lower-cost generic clopidogrel may increase patient compliance. However, platelet inhibition by ge..
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The Body Mass Index as a Prognostic Factor of Critical Care
So Yeon Lim, So I Kim, Yon Ju Ryu, Jin Hwa Lee, Eun Mi Chun, Jung Hyun Chang
Korean J Intern Med. 2010;25(2):162-167. Published online June 1, 2010
Background/AimsObesity is a worldwide concern, but its influence on critical care outcomes is not well understood. We tested the hypothesis that abnormal body mass index (BMI) would be an independent predictor of higher mortality rates in intensive care unit (ICU).
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The Contribution of Abdominal Obesity and Dyslipidemia to Metabolic Syndrome in Psychiatric Patients
Sung-Hwan Kim, Kiwon Kim, Mi Hyang Kwak, Hak Jin Kim, Hong-Sup Kim, Ki Hoon Han
Korean J Intern Med. 2010;25(2):168-173. Published online June 1, 2010
Background/AimsMetabolic syndrome is an emerging risk factor for cardiovascular disease. This study investigated the prevalence of metabolic syndrome among psychiatric patients in order to identify the dominant factors of metabolic syndrome. Methods
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Variable Association between Components of the Metabolic Syndrome and Electrocardiographic Abnormalities in Korean Adults
Hong-Kyu Kim, Chul-Hee Kim, Kwan-Ho Ko, Seong-Wook Park, Joong-Yeol Park, Ki-Up Lee
Korean J Intern Med. 2010;25(2):174-180. Published online June 1, 2010
Background/AimsResting electrocardiogram (ECG) abnormalities have been strongly associated with cardiovascular disease mortality. Little is known, however, about the association between individual components of metabolic syndrome and ECG abnormalities, especially in Asian popu..
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The Risk Factors and Outcome of Acute Kidney Injury in the Intensive Care Units
Woo Young Park, Eun Ah Hwang, Mi Hyun Jang, Sung Bae Park, Hyun Chul Kim
Korean J Intern Med. 2010;25(2):181-187. Published online June 1, 2010
Background/AimsAcute kidney injury (AKI) is a common and serious complication in critically ill patients, especially in the intensive care unit (ICU). The present study was performed to evaluate the occurrence rate of AKI using the RIFLE (increasing severity classes risk, inju..
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Comparison of Patients Starting Hemodialysis with Those Underwent Hemodialysis 15 Years Ago at the Same Dialysis Center in Korea
Su Jin Seok, Jung Hoon Kim, Hyo Wook Gil, Jong Oh Yang, Eun Young Lee, Sae Yong Hong
Korean J Intern Med. 2010;25(2):188-194. Published online June 1, 2010
Background/AimsMaintenance dialysis is made decreased the death rate of patients with end-stage renal disease; however, mortality is still high. The aim of this study was to identify the association between clinical parameters at the start of hemodialysis with survival and com..
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Serum Prohepcidin Levels in Helicobacter Pylori Infected Patients with Iron Deficiency Anemia
Sun-Young Lee, Eun Young Song, Yeo Min Yun, So Young Yoon, Yo Han Cho, Sung-Yong Kim, Mark Hong Lee
Korean J Intern Med. 2010;25(2):195-200. Published online June 1, 2010
Background/AimsHelicobacter pylori (H. pylori) infection appears to subvert the human iron regulatory mechanism and thus upregulates hepcidin, resulting in unexplained iron-deficiency anemia (IDA). We evaluated serum prohepcidin levels before ..
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Correlation of Anti-Cyclic Citrullinated Antibody with Hand Joint Erosion Score in Rheumatoid Arthritis Patients
Hyun Hee Kim, JiHun Kim, Sung-Hoon Park, Seong-Kyu Kim, Ok-Dong Kim, Jung-Yoon Choe
Korean J Intern Med. 2010;25(2):201-206. Published online June 1, 2010
Background/AimsTo examine the correlation between radiological joint damage and serological parameters in early rheumatoid arthritis (RA). MethodsThis retrospective study reviewed the records of 216 patients diagnosed with RA and classified them..
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The Current Practice of Skin Testing for Antibiotics in Korean Hospitals
So Hee Lee, Heung Woo Park, Sae Hoon Kim, Yoon Seok Chang, Sun Sin Kim, Sang Heon Cho, Kyung Up Min, You Young Kim
Korean J Intern Med. 2010;25(2):207-212. Published online June 1, 2010
Background/AimsAntibiotic skin testing is a useful procedure for identifying patients with IgE-mediated hypersensitivity to antibiotics. The procedures, however, have not been standardized, and the testing is performed with diverse protocols in Korean hospitals wards. Thus, we..
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Case Reports |
Two Lung Masses with Different Responses to Pemetrexed
Kwang Young Park, Jae Wook Jung, Seung Bum Nam, Ho Jin Lee, Hyo Seok Kim, Yoon Hee Choi, Jae Cheol Lee
Korean J Intern Med. 2010;25(2):213-216. Published online June 1, 2010
We described here a patient who had two lung masses. Although the two masses had the same histology and a similar good response to initial chemotherapy with gemcitabine and carboplatin, the response to pemetrexed as a second-line treatment was different after re-growth of the tumors. These two lu..
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A Case of Diabetic Neuropathy Combined with Guillain-Barre Syndrome
Heung-Yong Jin, Kyung-Ae Lee, So-Young Kim, Ji-Hyun Park, Hong-Sun Baek, Tae-Sun Park
Korean J Intern Med. 2010;25(2):217-220. Published online June 1, 2010
A 59-year-old man was admitted with numbness, pain, and a tingling sensation in both lower legs. He was initially diagnosed with diabetic peripheral neuropathy based on a symptom questionnaire and a quantitative sensory test. Despite symptomatic treatment of diabetic neuropathy, he complained of ..
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A Large Intrathoracic Meningocele in a Patient with Neurofibromatosis-1
Jae Wook Jeong, Kwang Young Park, Sang Min Yoon, Du Whan Choe, Cheol Hyeon Kim, Jae Cheol Lee
Korean J Intern Med. 2010;25(2):221-223. Published online June 1, 2010
A large intrathoracic meningocele, a saccular protrusion of the meninges through a dilated intervertebral foramen or a bony defect of the vertebral column, was diagnosed in a 41-year-old female patient showing clinical features of neurofibromatosis-1 (NF-1), including café-au-lait spots, cutane..
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Inflammatory Polyarthritis in a Patient with Psoriasis: Is It Psoriatic Arthritis or Rheumatoid Arthrirtis?
Kwang-Hoon Lee, Myoung-Kyun Son, You-Jung Ha, Sang-Tae Choi, Sang-Won Lee, Yong-Beom Park, Soo-Kon Lee
Korean J Intern Med. 2010;25(2):224-226. Published online June 1, 2010
Psoriatic arthritis (PsA) is an inflammatory arthritis associated with psoriasis. There are no generally accepted diagnostic criteria for PsA. Indeed, the diagnosis of this inflammatory arthritis is made by exclusion of other possible diseases and based upon immunologic, radiologic, and clinical ..
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