Original Articles |
Hepatocyte nuclear factor 1-alpha mutation in normal glucose-tolerant subjects and early-onset type 2 diabetic patients
Dong Mee Lim, Nam Huh, Keun Yong Park
Korean J Intern Med. 2008;23(4):165-169. Published online December 29, 2008
Background/AimsThe prevalence of diabetes in Korea is reported to be approximately 10%, but cases of maturity-onset diabetes of the young (MODY) are rare in Korea. A diagnostic technique for autosomal dominant MODY is being actively sought. In this regard, we used a DNA chip t..
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Factors for poor prognosis of near-fatal asthma after recovery from a life-threatening asthma attack
Myung-Shin Kim, Young-Joo Cho, Hee-Bom Moon, Sang Heon Cho
Korean J Intern Med. 2008;23(4):170-175. Published online December 29, 2008
Background/AimsThe aim of this study was to investigate poor prognostic factors associated with a near-fatal asthma attack following patient recovery. MethodsWe enrolled 68 patients who suffered near-fatal asthma attacks and w..
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Effects of dehydroepiandrosterone on Th2 cytokine production in peripheral blood mononuclear cells from asthmatics
Inseon S. Choi, Yong Cui, Young-Ah Koh, Hyun-Chul Lee, Yong-Bum Cho, Young-Ho Won
Korean J Intern Med. 2008;23(4):176-181. Published online December 30, 2008
Background/AimsThe androgen dehydroepiandrosterone (DHEA) attenuates allergic inflammatory airway reactions by down-regulating the Th2 response in mice. The purpose of this study was to investigate whether DHEA suppresses Th2 cytokine production in cultured peripheral blood m..
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Autologous stem cell transplantation for diffuse large B-cell lymphoma with residual extranodal involvement
Ock Bae Ko, Geundoo Jang, Shin Kim, Jooryung Huh, Cheolwon Suh
Korean J Intern Med. 2008;23(4):182-190. Published online December 29, 2008
Background/AimsDiffuse large B-cell lymphoma (DLBCL) in Koreans is frequently accompanied by extranodal (EN) disease at the time of autologous stem cell transplantation (ASCT). We sought to determine whether high EN involvement affected survival following ASCT in Koreans. <..
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Relationship between serum brain natriuretic peptide and heart function in patients with chronic kidney disease
Jae Won Yang, Min Soo Kim, Jae Seok Kim, Jong Myoung Yoo, Seung Tae Han, Bi Ro Kim, Yun Deok Kim, Jeong Wook Choi, Seung Ok Choi, Byoung Geun Han
Korean J Intern Med. 2008;23(4):191-200. Published online December 30, 2008
Background/AimsBrain natriuretic peptide (BNP) levels are known to be elevated in patients with chronic kidney disease (CKD) and normal heart function. Therefore, the present study was performed to examine the effectiveness of BNP level in diagnosing heart failure in patients ..
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Polymorphism in the promoter region of the klotho gene (G-395A) is associated with early dysfunction in vascular access in hemodialysis patients
Youngsu Kim, Sun Joo Jeong, Hyung Suk Lee, Eun Jung Kim, Young Rim Song, Sung Gyun Kim, Ji Eun Oh, Young Ki Lee, Jang Won Seo, Jong Woo Yoon, Ja-Ryong Koo, Hyung Jik Kim, Jung Woo Noh, Seung Ho Park
Korean J Intern Med. 2008;23(4):201-207. Published online December 30, 2008
Background/AimsVascular access dysfunction is an important cause of morbidity and mortality in hemodialysis (HD) patients. Recent studies have shown that a klotho gene mutation is related to endothelial dysfunction, thrombosis, and arteriosclerosis, which are ..
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Case Reports |
A case of blue rubber bleb nevus syndrome
Seung-Hwan Shin, Hiun-Suk Chae, Jeong-Seon Ji, Hyung-Keun Kim, Young-Seok Cho, Eun-Deok Chang, Kyu-Yong Choi
Korean J Intern Med. 2008;23(4):208-212. Published online December 30, 2008
Blue rubber bleb nevus syndrome is a rare disorder that is characterized by multiple recurrent vascular malformations, such as hemangioma, and these primarily involve the skin and the gastrointestinal tract. It may also involve the brain, liver, lungs, and skeletal muscles. A 14-year-old female v..
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A case of scar sarcoidosis
Young Chul Hong, Dong Jib Na, Sang Hoon Han, Yang Deok Lee, Yong Seon Cho, Min Soo Han
Korean J Intern Med. 2008;23(4):213-215. Published online December 30, 2008
Infiltration of sarcoid granuloma in old cutaneous scars is one of the uncommon cutaneous manifestations of sarcoidosis. Here, we report the case of a 47-year-old female who presented with swelling and irritation in 5 old scars. She had acquired these scars 9 years ago in a traffic accident. An i..
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A case of congenital bilateral coronary-to-right ventricle fistula coexisting with variant angina
Se-Na Jang, Sung-Ho Her, Kyong-Rock Do, Joon-Sung Kim, Hee-Jeong Yoon, Jong-Min Lee, Seung-Won Jin
Korean J Intern Med. 2008;23(4):216-218. Published online December 30, 2008
A coronary arteriovenous (AV) fistula consists of a communication between a coronary artery and a cardiac chamber, a great artery or the vena cava. It is the most common anomaly that can affect coronary perfusion. Yet bilateral involvement of a coronary fistula, constitutes an uncommon subgroup o..
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A case of granulomatous lung disease in a patient with Good's syndrome
Seung Heon Lee, Sang-Min Lee, Seok-Chul Yang, Chul-Gyu Yoo, Young Whan Kim, Young-Soo Shim, Sung Koo Han
Korean J Intern Med. 2008;23(4):219-222. Published online December 30, 2008
Good's syndrome is extremely rare. This adult-onset condition is characterized by a thymoma with immunodeficiency, low B- and T-cell counts, and hypo-gammaglobulinemia. The initial clinical presentation is either a mass-lesion thymoma or a recurrent infection. Patients with Good's syndrome are ve..
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