Reviews |
Autosomal Dominant Polycystic Kidney Disease: 2009 Update for Internists
William M. Bennett
Korean J Intern Med. 2009;24(3):165-168. Published online August 26, 2009
Because autosomal dominant polycystic kidney disease (ADPKD) is one of the most common genetic abnormalities seen in today's medical practice, many internists will likely treat patients affected by this condition. Genetic abnormalities have been increasingly recognized, and the pathophysiology of..
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Update on Endoscopic Treatment of Chronic Pancreatitis
Byung Moo Yoo, Glen A. Lehman
Korean J Intern Med. 2009;24(3):169-179. Published online August 26, 2009
Endoscopic therapy has been increasingly recognized as the effective therapy in selected patients with chronic pancreatitis. Utility of endotherapy in various conditions occurring in chronic pancreatitis is discussed. Its efficacy, limitations, and alternatives are addressed. For the best managem..
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Editorial |
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Original Articles |
Early Detection Of Asymptomatic Coronary Artery Disease In Patients With Type 2 Diabetes Mellitus
Won Sang Yoo, Hee Jin Kim, Dohee Kim, Myung Yong Lee, Hyun-Kyung Chung
Korean J Intern Med. 2009;24(3):183-189. Published online August 26, 2009
Background/AimsIn type 2 diabetic patients, coronary artery disease (CAD) is usually detected at an advanced stage due to a lack of symptoms. The aim of this study was to define which clinical parameters or non-invasive tests predict CAD in asymptomatic type 2 diabetic patients..
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Endoscopic Pancreatic Sphincterotomy: Indications and Complications
Yong Won Joo, Jai Hoon Yoon, Seung Chul Cho, Kang Nyeong Lee, Na Rae Ha, Hang Lak Lee, Oh Young Lee, Byung Chul Yoon, Ho Soon Choi, Joon Soo Hahm, Dong Hoo Lee, Min Ho Lee
Korean J Intern Med. 2009;24(3):190-195. Published online August 26, 2009
Background/AimsAlthough a few recent studies have reported the effectiveness of endoscopic pancreatic sphincterotomy (EPST), none has compared physicians' skills and complications resulting from the procedure. Thus, we examined the indications, complications, and safety of EPS..
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Endoscopic and Histopathologic Predictors of Recurrence of Colorectal Adenoma on Lowering the Miss Rate
Jeong-Seon Ji, Kyu-Yong Choi, Won-Chul Lee, Bo-In Lee, Soo-Heon Park, Hwang Choi, Byung-Wook Kim, Hiun-Suk Chae, Yong-Moon Park, Young-Jun Park
Korean J Intern Med. 2009;24(3):196-202. Published online August 26, 2009
Background/AimsAlthough colorectal adenoma is reported to recur frequently, this may result from missing it at baseline. However, few studies of recurrence have considered the miss rate. This study evaluated the recurrence rate prospectively and clinical predictors of recurren..
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Assessment of the Efficacy of Reducing Peginterferon Alfa-2a and Ribavirin Dose on Virologic Response in Koreans with Chronic Hepatitis C
Jung Hyun Kwon, Si Hyun Bae, Jong Young Choi, Seung Kew Yoon, Kwan Soo Byun, Seung Woon Paik, Young Suk Lim, Han Chu Lee, Kwang Hyub Han, Kwan Sik Lee
Korean J Intern Med. 2009;24(3):203-211. Published online August 26, 2009
Background/AimsThe virologic response of Koreans to combination therapy for chronic hepatitis C is similar to westerns; however, dose modification occurs more frequently in Koreans. We evaluated the rates of peginterferon α-2a and ribavirin dose modifications and their effect o..
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Significance of Inflammatory Markers in Diabetic Patients with Stable Coronary Artery Disease
Hyo-Jin Lee, Sung-Ho Her, Yun-Sun Im, Kang-Yeon Won, Sun-Hong Yoo, Dong-Bin Kim, Dong-Il Shin, Pum-Joon Kim, Ki-Bae Seung, Jae-Hyung Kim, Keon-Yeop Kim
Korean J Intern Med. 2009;24(3):212-219. Published online August 26, 2009
Background/AimsPatients with diabetes are prone to coronary artery disease (CAD); however, the majority of diabetic patients show normal coronary arteries. We examined differences in the clinical aspects of diabetic patients with insignificant and with significant stenosis of ..
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Selectively Decreased Expression of Peroxiredoxins Induced by Silica in Pulmonary Epithelial Cells
Hye Lim Lee, Young Sun Kim, Joo Hun Park, Wou Young Chung, Kyu Sung Lee, Yoon Jung Oh, Seung Soo Sheen, Kwang Joo Park, Sung Chul Hwang
Korean J Intern Med. 2009;24(3):220-226. Published online August 26, 2009
Background/AimsPeroxiredoxin (Prx) belongs to a ubiquitous family of antioxidant enzymes that regulates many cellular processes through intracellular oxidative signal transduction pathways. Silica-induced lung damage involves reactive oxygen species (ROS) that trigger subseque..
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Long-Term Effects of Rosiglitazone on the Progressive Decline in Renal Function in Patients With Type 2 Diabetes
Mee Kyoung Kim, Seung-Hyun Ko, Ki-Hyun Baek, Yu-Bae Ahn, Kun-Ho Yoon, Moo-Il Kang, Kwang-Woo Lee, Ki-Ho Song
Korean J Intern Med. 2009;24(3):227-232. Published online August 26, 2009
Background/AimsThiazolidinediones reduce urinary albumin excretion and may prevent the development of renal injury. We evaluated the long-term effects of rosiglitazone on the progression of renal dysfunction in patients with type 2 diabetes mellitus. Metho..
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The Efficacy and Safety of Ezetimibe and Low-Dose Simvastatin as a Primary Treatment for Dyslipidemia in Renal Transplant Recipients
Hye Eun Yoon, Joon Chang Song, Bok Jin Hyoung, Hyeon Seok Hwang, So Young Lee, Youn Joo Jeon, Bum Soon Choi, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2009;24(3):233-237. Published online August 26, 2009
Background/AimsThe efficacy and safety of a combination of ezetimibe and low-dose statin as primary treatment for dyslipidemia in renal transplant patients were evaluated prospectively. MethodsThe study enrolled 77 renal transplant recipients wi..
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Pretreatment with Darbepoetin Attenuates Renal Injury in a Rat Model of Cisplatin-Induced Nephrotoxicity
Dae Eun Choi, Jin Young Jeong, Beom Jin Lim, Kang Wook Lee, Young-Tai Shin, Ki-Ryang Na
Korean J Intern Med. 2009;24(3):238-246. Published online August 26, 2009
Background/AimsDarbepoetin alfa (DPO) exhibits comparable renoprotective effects to erythropoietin (EPO) in several animal models of acute renal injury. We examined whether DPO also attenuated renal injury in a rat model of cisplatin nephrotoxicity. Method..
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Paraquat Intoxication in Subjects Who Attempt Suicide: Why They Chose Paraquat
Su-Jin Seok, Hyo-Wook Gil, Du-Shin Jeong, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2009;24(3):247-251. Published online August 26, 2009
Background/AimsParaquat (PQ) has been used in suicide attempts; an estimated 2,000 toxic ingestions occur annually, with 60-70% mortality. We sought to determine why PQ is such a common agent for suicide attempts in Korea. MethodsWe analyzed 250..
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Bone Marrow T Cells are Superior to Splenic T Cells to Induce Chimeric Conversion After Non-Myeloablative Bone Marrow Transplantation
Hyun-Sil Park, Seok-Goo Cho, Min-Jung Park, So-Youn Min, Hong-Seok Chang, Hee-Je Kim, Seok Lee, Chang-Ki Min, Jong-Wook Lee, Woo-Sung Min, Chun-Choo Kim, Ho-Youn Kim
Korean J Intern Med. 2009;24(3):252-262. Published online August 26, 2009
Background/AimsThe bone marrow functions not only as the primary B-lymphocyte-producing organ but also as a secondary lymphoid organ for CD4 and CD8 cell responses and a site of preferential homing and persistence for memory T cells. Bone marrow T (BM-T) cells are distinguishe..
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Blood Stream Infections by Candida glabrata and Candida krusei: A Single-Center Experience
Hee Kyoung Choi, Su Jin Jeong, Han Sung Lee, Bum Sik Chin, Suk Hoon Choi, Sang Hoon Han, Myung Soo Kim, Chang Oh Kim, Jun Yong Choi, Young Goo Song, June Myung Kim
Korean J Intern Med. 2009;24(3):263-269. Published online August 26, 2009
Background/AimsThe increasing incidence of Candida glabrata and Candida krusei infections is a significant problem because they are generally more resistant to fluconazole. We compared the risk factors associated with C. glabrata
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Case Reports |
A Case of Idiopathic Adulthood Ductopenia
Byeong Chool Park, Seon Mee Park, Eun Young Choi, Hee Bok Chae, Se Jin Yoon, Rohyun Sung, Sung Koo Lee
Korean J Intern Med. 2009;24(3):270-273. Published online August 26, 2009
Idiopathic adulthood ductopenia (IAD) is a chronic cholestatic liver disease of unknown etiology characterized by adult onset, an absence of autoantibodies, inflammatory bowel disease, and a loss of interlobular bile ducts. In the present report, a case fulfilling the IAD criteria is described. A..
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A Synonymous Genetic Alteration of LMX1B in a Family with Nail-Patella Syndrome
Joo Ho Ham, Seok Joon Shin, Kyu Re Joo, Sung Min Park, Hye Young Sung, Joong Seok Kim, Jin Soo Choi, Yeong Jin Choi, Ho Cheol Song, Eui Jin Choi
Korean J Intern Med. 2009;24(3):274-278. Published online August 26, 2009
The gene responsible for nail-patella syndrome, LMX1B, has recently been identified on chromosome 9q. Here we present a patient with nail-patella syndrome and an autosomal dominant pattern of inheritance. A 17-year-old girl visited our clinic for the evaluation and treatment of p..
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Chinese Bellflower Root Anaphylaxis: IgE-Binding Components and Cross-Reactivity With Mugwort and Birch
Sae-Hoon Kim, Sang-Min Lee, Heung-Woo Park, Sang-Heon Cho, Kyung-Up Min, You-Young Kim, Yoon-Seok Chang
Korean J Intern Med. 2009;24(3):279-282. Published online August 26, 2009
A 56-year-old man who had suffered from seasonal rhinitis in spring and autumn experienced recurrent generalized urticaria and an oral burning sensation after eating several cooked herbs for 3 months. A skin-prick test showed positive responses to various pollens, celery, Chinese bellflower, and ..
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A New Onset of Systemic Lupus Erythematosus Developed After Bee Venom Therapy
Young Hee Rho, Jin-Hyun Woo, Seong Jae Choi, Young Ho Lee, Jong Dae Ji, Gwan Gyu Song
Korean J Intern Med. 2009;24(3):283-285. Published online August 26, 2009
Lupus is a systemic autoimmune disease of an unknown origin, and systemic lupus erythematosus (SLE) can be triggered by numerous stimuli. Bee venom therapy is an alternative therapy that is believed to be effective for various kinds of arthritis. We present here a case of a 49-year-old female who..
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