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Review
How lessons learned from the 2015 Middle East respiratory syndrome outbreak affected the response to coronavirus disease 2019 in the Republic of Korea
Tae Un Yang, Ji Yun Noh, Joon-Young Song, Hee Jin Cheong, Woo Joo Kim
Korean J Intern Med. 2021;36(2):271-285. Published online February 5, 2021
The Republic of Korea (ROK) experienced a public health crisis due to Middle East respiratory syndrome (MERS) in 2015 and is currently going through the coronavirus disease 2019 (COVID-19) pandemic. Lessons learned from the disastrous MERS outbreak were ref lected in the preparedness system, and the..
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Review
Severe hypoglycemia as a preventable risk factor for cardiovascular disease in patients with type 2 diabetes mellitus
Soo-Yeon Choi, Seung-Hyun Ko
Korean J Intern Med. 2021;36(2):263-270. Published online January 8, 2021
Glucose-lowering medication and lifestyle modification are essential for optimal glycemic control in patients with type 2 diabetes mellitus (T2DM). However, glucose-lowering agents, particularly insulin and insulin secretagogues, may cause hypoglycemia, which has multiple negative effects on the car..
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Review
Angiotensin-converting enzyme 2 and kidney diseases in the era of coronavirus disease 2019
Sang Heon Suh, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae
Korean J Intern Med. 2021;36(2):247-262. Published online October 16, 2020
In the decades since the discovery of angiotensin-converting enzyme 2 (ACE2), its protective role in terms of antagonizing activation of the classical renin-angiotensin system (RAS) axis has been recognized in clinical and experimental studies on kidney and cardiovascular diseases. The effects of AC..
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Review
Recent advances in the management of difficult bile-duct stones: a focus on single-operator cholangioscopy-guided lithotripsy
Chi Hyuk Oh, Seok Ho Dong
Korean J Intern Med. 2021;36(2):235-246. Published online December 1, 2020
The most effective and the standard treatment for bile duct stones (BDSs) is endoscopic retrograde cholangiopancreatography (ERCP). However, in 10% to 15% of patients with BDSs, the stones cannot be removed by conventional ERCP, which involves endoscopic sphincterotomy followed by balloon or basket ..
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Corrigendum
Nontuberculous mycobacterial infection in rheumatoid arthritis patients: a single-center experience in South Korea
Doo-Ho Lim, Yong-Gil Kim, Tae Sun Shim, Kyung-Wook Jo, Byeongzu Ghang, Soo Min Ahn, Seokchan Hong, Chang-Keun Lee, Bin Yoo
Korean J Intern Med. 2021;36(1):234-234. Published online January 1, 2021
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Image of interest
Renal coloboma syndrome with epilepsy
Jitong Li, Cuihua Liu
Korean J Intern Med. 2021;36(1):232-233. Published online September 18, 2020
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Image of interest
Unusual case of abdominal wall pseudohernia in a patient with acute constipation
Tae Hee Lee
Korean J Intern Med. 2021;36(1):228-229. Published online June 19, 2020
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Image of interest
Total ankylosis of the bilateral hand and wrist joints in a patient with ankylosing spondylitis
Shin-Gil Kim, Kyung-Ann Lee
Korean J Intern Med. 2021;36(1):226-227. Published online September 16, 2020
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Rheumatology / Original Article
Association of body composition with disease activity and disability in rheumatoid arthritis
Kyeong Min Son, Seong Hun Kang, Young Il Seo, Hyun Ah Kim
Korean J Intern Med. 2021;36(1):214-222. Published online May 15, 2020
Background/Aims: To explore the associations between body composition and pain, disease activity, and disability in rheumatoid arthritis (RA).
Methods: The study enrolled 335 patients with RA and underwent body composition measurement with an InBody analyzer. The associations of body mass index (BM..
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Infectious diseases / Original Article
Ongoing outbreak of human adenovirus-associated acute respiratory illness in the Republic of Korea military, 2013 to 2018
Jae-Hoon Ko, Hyeong-taek Woo, Hong Sang Oh, Song Mi Moon, Joon Young Choi, Jeong Uk Lim, Donghoon Kim, Junsu Byun, Soon-Hwan Kwon, Daeyoun Kang, Jung Yeon Heo, Kyong Ran Peck
Korean J Intern Med. 2021;36(1):205-213. Published online September 5, 2019
Background/Aims: Human adenovirus type 55 (HAdV-55), an emerging epidemic strain, has caused several large outbreaks in the Korean military since 2014, and HAdV-associated acute respiratory illness (HAdV-ARI) has been continuously reported thereafter.
Methods: To evaluate the epidemiologic characte..
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Hemato-oncology / Original Article
Treatment outcome and prognostic factors of Korean patients with chronic lymphocytic leukemia: a multicenter retrospective study
Yunsuk Choi, Jung-Hee Lee, Chul Won Jung, Jae-Cheol Jo, Jin Seok Kim, Inho Kim, Silvia Park, June-won Cheong, Sang-Hyuk Park, Sung-Yong Kim, Hong-Ghi Lee
Korean J Intern Med. 2021;36(1):194-204. Published online April 14, 2020
Background/Aims: Compared with Western countries, chronic lymphocytic leukemia (CLL) rarely occurs in Asia and has different clinical characteristics. Thus, we aimed to evaluate the clinical characteristics, treatment outcomes, and prognostic significance of Korean patients with CLL.
Methods: We re..
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Hemato-oncology / Original Article
Maintenance chemotherapy after 6 cycles of platinum-doublet regimen in anthracycline-and taxane-pretreated metastatic breast cancer
Eun Kyo Joung, Ji Hyun Yang, Sooeun Oh, Se Jun Park, Jieun Lee
Korean J Intern Med. 2021;36(1):182-193. Published online February 28, 2020
Background/Aims: Sequential monotherapy is recommended for anthracycline-and taxane-resistant metastatic breast cancer (MBC), but combination chemotherapy is considered in patients with visceral crisis. Cisplatin-doublet chemotherapy is a combination regimen for MBC, but prolonged treatment is chall..
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Hemato-oncology / Original Article
Role of concurrent chemoradiation on locally advanced unresectable adenoid cystic carcinoma
Hyerim Ha, Bhumsuk Keam, Chan-Young Ock, Tae Min Kim, Jin Ho Kim, Eun-Jae Chung, Seong Keun Kwon, Soon-Hyun Ahn, Hong-Gyun Wu, Myung-Whun Sung, Dae Seog Heo
Korean J Intern Med. 2021;36(1):175-181. Published online March 30, 2020
Background/Aims: Adenoid cystic carcinoma (ACC) is a rare salivary gland tumor characterized by indolence, with a high rate of local recurrence and distant metastasis. This study aimed to investigate the effect of concurrent chemoradiation (CCRT) on locally advanced unresectable ACC.
Methods: We re..
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Nephrology / Original Article
Usefulness of BK virus-specific interferon-γ enzyme-linked immunospot assay for predicting the outcome of BK virus infection in kidney transplant recipients
Hyunjoo Bae, Do Hyun Na, Ji-Yeun Chang, Ki Hyun Park, Ji Won Min, Eun Jeong Ko, Hyeyoung Lee, Chul Woo Yang, Byung Ha Chung, Eun-Jee Oh
Korean J Intern Med. 2021;36(1):164-174. Published online April 3, 2020
Background/Aims: To investigate if BK virus (BKV)-specific T cell immunity measured by an interferon-γ enzyme-linked immunospot (ELISPOT) assay can predict the outcome of BK virus infection in kidney transplant recipients (KTRs). Methods: We included 68 KTRs with different viremia status (no virem..
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Endocrinology-metabolism / Original Article
Incidence and risk factors for osteoporotic fractures in patients with systemic lupus erythematosus versus matched controls
Chang Seong Kim, Kyung-Do Han, Jin Hyung Jung, Hong Sang Choi, Eun Hui Bae, Seong Kwon Ma, Soo Wan Kim
Korean J Intern Med. 2021;36(1):154-163. Published online June 26, 2019
Background/Aims: Despite recent improvements in the quality of life of patients with systemic lupus erythematosus (SLE), osteoporosis, and osteoporotic fractures are one of the major complications of SLE. Furthermore, limited data are available on the incidence and predictor of osteoporotic fracture..
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Pulmonology / Original Article
Effect of corticosteroid therapy in the early phase of acute respiratory distress syndrome: a propensity-matched cohort study
Moon Seong Baek, Yunkyoung Lee, Sang-Bum Hong, Chae-Man Lim, Younsuck Koh, Jin Won Huh
Korean J Intern Med. 2021;36(1):145-153. Published online March 5, 2020
Background/Aims: It is unclear whether corticosteroid use in patients with acute respiratory distress syndrome (ARDS) improves survival. This study aimed to investigate whether the administration of corticosteroids to patients in the early phase of moderate to severe ARDS is associated with improved..
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