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Letter to the editor
Funtional significance of the intermediate lesion in a single coronary artery assessed by fractional flow reserve
Sang Jin Ha, Se Hwan Kwon, Soo-Joong Kim
Korean J Intern Med. 2014;29(6):822-824. Published online October 31, 2014
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Rheumatology / Original Article
Complex repetitive discharge on electromyography as a risk factor for malignancy in idiopathic inflammatory myopathy
Na Ri Kim, Eon Jeong Nam, Jong Wan Kang, Hyun Seok Song, Churl Hyun Im, Young Mo Kang
Korean J Intern Med. 2014;29(6):814-821. Published online October 31, 2014
Background/Aims: We investigated the electromyography (EMG) findings and demographic, clinical, and laboratory features that may predict the development of malignancy in patients with idiopathic inflammatory myopathy (IIM).
Methods: In total, 61 patients, 36 with dermatomyositis and 25 with polymyo..
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Allergy / Original Article
Clinical features of elderly chronic urticaria
Ga-Young Ban, Mi-Yea Kim, Hye-Soo Yoo, Dong-Ho Nahm, Young-Min Ye, Yoo-Seob Shin, Hae-Sim Park
Korean J Intern Med. 2014;29(6):800-806. Published online October 31, 2014
Background/Aims: Chronic urticaria (CU) is defined as itchy wheals lasting 6 weeks or more. As the aged population increases worldwide, it is essential to identify the specific features of this disease in the elderly population.
Methods: We investigated the prevalence and clinical features of CU in..
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Cardiology / Original Article
The diagnostic utility of chest computed tomography scoring for the assessment of amiodarone-induced pulmonary toxicity
In Sook Kang, Kyung Jin Kim, Yookyung Kim, Seong-Hoon Park
Korean J Intern Med. 2014;29(6):746-753. Published online October 31, 2014
Background/Aims: Amiodarone is one of the most widely used antiarrhythmic agents; however, amiodarone-induced pulmonary toxicity (APT) can be irreversible and sometimes fatal. The aim of this study was to evaluate the feasibility of chest computed tomography (CT) as a diagnostic tool for APT and to ..
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Hemato-oncology / Review
Recent advances in treatment of aplastic anemia
Seung Hwan Shin, Sung Eun Lee, Jong Wook Lee
Korean J Intern Med. 2014;29(6):713-726. Published online October 31, 2014
Recent advances in the treatment of aplastic anemia (AA) made most of patients to expect to achieve a long-term survival. Allogeneic stem cell transplantation (SCT) from HLA-matched sibling donor (MSD-SCT) is a preferred first-line treatment option for younger patients with severe or very severe AA,..
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Cardiology / Review
The scientific achievements of the decades in Korean Acute Myocardial Infarction Registry
Hyun Kuk Kim, Myung Ho Jeong, Seung Hun Lee, Doo Sun Sim, Young Joon Hong, Youngkeun Ahn, Chong Jin Kim, Myeong Chan Cho, Young Jo Kim
Korean J Intern Med. 2014;29(6):703-712. Published online October 31, 2014
The Korea Acute Myocardial Infarction Registry (KAMIR) was the first nationwide registry data collection designed to track outcomes of patients with acute myocardial infarction (AMI). These studies ref lect the current therapeutic approaches and management for AMI in Korea. The results of KAMIR coul..
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Cardiology / Review
Role of modern 3D echocardiography in valvular heart disease
Takahiro Shiota
Korean J Intern Med. 2014;29(6):685-702. Published online October 31, 2014
Three-dimensional (3D) echocardiography has been conceived as one of the most promising methods for the diagnosis of valvular heart disease, and recently has become an integral clinical tool thanks to the development of high quality real-time transesophageal echocardiography (TEE). In particular, fo..
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Hemato-oncology / Original Article
Etanercept for steroid-refractory acute graft versus host disease following allogeneic hematopoietic stem cell transplantation
Joo Han Park, Hyo Jung Lee, Sei Rhan Kim, Ga Won Song, Seung Kyong Lee, Sun Young Park, Ki Chan Kim, Sun Hyuk Hwang, Joon Seong Park
Korean J Intern Med. 2014;29(5):630-636. Published online August 28, 2014
Background/Aims: The treatment for steroid-refractory acute graft versus host disease (GVHD) after allogeneic stem cell transplantation (allo-SCT) needs to be standardized. We report our clinical experience with etanercept for steroid-refractory acute GVHD.
Methods: Eighteen patients who underwent ..
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Pulmonology / Original Article
Factors predictive of the failure of medical treatment in patients with pleural infection
Sung-Kyoung Kim, Chul Ung Kang, So Hyang Song, Deog Gon Cho, Kyu Do Cho, Chi Hong Kim
Korean J Intern Med. 2014;29(5):603-612. Published online August 28, 2014
Background/Aims: The clinical outcomes of some patients with pleural infection may be favorable with medical treatment alone, but in others, the disease progresses and requires additional surgical treatment. However, little is known about the factors affecting this difference. The aim of this study ..
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Gastroenterology / Original Article
A novel prognostic factor for hepatocellular carcinoma: protein disulfide isomerase
Su Jong Yu, Jae-Kyung Won, Han Suk Ryu, Won-Mook Choi, Hyeki Cho, Eun-Ju Cho, Jeong-Hoon Lee, Yoon Jun Kim, Kyung-Suk Suh, Ja-June Jang, Chung Yong Kim, Hyo-Suk Lee, Jung-Hwan Yoon, Kwang-Hyun Cho
Korean J Intern Med. 2014;29(5):580-587. Published online August 28, 2014
Background/Aims: Protein disulfide isomerase (PDI) has been implicated in the survival and progression of some cancer cells, by compensating for endoplasmic reticulum stress by upregulating the protein-folding capacity. However, its prognostic role in patients with hepatocellular carcinoma (HCC) has..
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Cardiology / Review
Recent technological updates and clinical applications of induced pluripotent stem cells
Sebastian Diecke, Seung Min Jung, Jaecheol Lee, Ji Hyeon Ju
Korean J Intern Med. 2014;29(5):547-557. Published online August 28, 2014
Induced pluripotent stem cells (iPSCs) were first described in 2006 and have since emerged as a promising cell source for clinical applications. The rapid progression in iPSC technology is still ongoing and directed toward increasing the efficacy of iPSC production and reducing the immunogenic and t..
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Letter to the editor
Recurrent neutropenia induced by rifabutin in a renal transplant recipient
Ji Yeun Chang, Eun Gyo Jeong, Ji Hyun Yu, Byung Ha Chung, Chul Woo Yang
Korean J Intern Med. 2014;29(4):532-534. Published online June 27, 2014
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Letter to the editor
A case of myocardial involvement in lung cancer that mimics ST segment elevation in myocardial infarction
Kye Hun Kim, Myung Ho Jeong, Hyun Ju Yoon, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang
Korean J Intern Med. 2014;29(4):525-528. Published online June 27, 2014
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Nephrology / Original Article
Effects of pretransplant plasmapheresis and rituximab on recurrence of focal segmental glomerulosclerosis in adult renal transplant recipients
Hoon Suk Park, Yuah Hong, In O Sun, Byung Ha Chung, Hyung Wook Kim, Bum Soon Choi, Cheol Whee Park, Dong Chan Jin, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2014;29(4):482-488. Published online June 27, 2014
Background/Aims: Recurrent focal segmental glomerulosclerosis (FSGS) following renal transplantation is relatively common. However, the risk factors and optimal pretransplant treatment preventing recurrence of FSGS remain controversial.
Methods: We retrospectively reviewed 27 adult renal transplan..
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Letter to the editor
A case of Wegener’s granulomatosis mimicking recurrent hemophagocytic lymphohistiocytosis
Sung Min Jung, Yun Hwa Jung, Hyun Jin Noh, In Sook Woo, Chi Wha Han
Korean J Intern Med. 2014;29(3):393-397. Published online April 29, 2014
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Case Report
Distant subcutaneous recurrence of a parathyroid carcinoma: abnormal uptakes in the 99mTc-sestamibi scan and 18F-FDG PET/CT imaging
Sang Soo Kim, Yun Kyung Jeon, Soo Hyung Lee, Bo Hyun Kim, Seong Jang Kim, Yong Ki Kim, In Ju Kim
Korean J Intern Med. 2014;29(3):383-387. Published online April 29, 2014
We report a rare case of distant subcutaneous parathyroid carcinoma recurrence. A 50‑year-old woman was referred to our hospital because of sustained hypercalcemia despite surgical removal of a parathyroid carcinoma. A focal uptake in the upper mediastinal area was detected in a 99mTc-s..
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Case Report
A case of ampullary gangliocytic paraganglioma
Ju-Il Yang, Jung-Sik Choi, Ga-Hee Lee, Byeong-Woo Kim, Seok-Jun Moon, Mi Seon Kang, Hyo Jung Ahn
Korean J Intern Med. 2014;29(3):375-378. Published online April 29, 2014
Gangliocytic paragangliomas (GPs) are rare tumors of the duodenum, presenting as single sessile or pedunculated polypoid masses. Clinical manifestations of duodenal GPs can vary from an incidental finding at endoscopy to frequent upper gastrointestinal bleeding caused by mucosal ulceration and abdom..
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Gastroenterology / Original Article
Survey of perinatal hepatitis B virus transmission after Korean National Prevention Program in a tertiary hospital
Jae Hoon Kim, Ju Seung Kim, Jong Joon Lee, Jung Ho Kim, Suk Young Kim, Young Kul Jung, Oh Sang Kwon, Yun Soo Kim, Duck Joo Choi, Ju Hyun Kim
Korean J Intern Med. 2014;29(3):307-314. Published online April 29, 2014
Background/Aims: The Ministry of Health and Welfare and the Korea Centers for Disease Control and Prevention in South Korea have been organizing hepatitis B virus (HBV) vertical infection prevention projects since July 2002. In this single-institute study, the results of surveys conducted in ..
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Pulmonology / Review
Modifiers of TGF-b1 effector function as novel therapeutic targets of pulmonary fibrosis
Chang-Min Lee, Jin Wook Park, Won-Kyung Cho, Yang Zhou, Boram Han, Pyoung Oh Yoon, Jeiwook Chae, Jack A Elias, Chun Geun Lee
Korean J Intern Med. 2014;29(3):281-290. Published online April 29, 2014
Pulmonary fibrosis is a fatal progressive disease with no effective therapy. Transforming growth factor (TGF)-b1 has long been regarded as a central mediator of tissue fibrosis that involves multiple organs including skin, liver, kidney, and lung. Thus, TGF-b1 and its signaling pathways have been at..
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Case Report
Isolated dilatation of the inferior vena cava
Jae-Joon Kim, Kyoung-Im Cho, Ji-Hoon Kang, Ja-Jun Goo, Kyoung-Nyoun Kim, Ja-Young Lee, Seong-Man Kim
Korean J Intern Med. 2014;29(2):241-245. Published online February 27, 2014
The diameter and collapsibility of the inferior vena cava (IVC) should be interpreted in consideration with other clinical and echocardiographic parameters before drawing definitive diagnostic conclusions. We report a case of a 46-year-old female with isolated IVC dilation and diminished inspiratory..
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