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Hemato-oncology / Original Article
The prognostic impact of inflammatory factors in patients with multiple myeloma treated with thalidomide in Korea
Cheolsu Kim, Ho Sup Lee, Chang-Ki Min, Je Jung Lee, Kihyun Kim, Dok Hyun Yoon, Hyeon Seok Eom, Hyewon Lee, Won Sik Lee, Ho-Jin Shin, Ji Hyun Lee, Yong Park, Jae-Cheol Jo, Young Rok Do, Yeung-Chul Mun
Korean J Intern Med. 2015;30(5):675-683. Published online August 27, 2015
Background/Aims: The purpose of this study was to determine the correlations between inflammatory factors—including absolute lymphocyte count, lactate dehydrogenase, β2-microglobulin, albumin, C-reactive protein, and ferritin—and the prognosis for survival in patients with multiple myeloma (MM) ..
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Infectious diseases / Original Article
Utilization of the respiratory virus multiplex reverse transcription-polymerase chain reaction test for adult patients at a Korean tertiary care center
Mi Young Ahn, Seong-Ho Choi, Jin-Won Chung, Hye Ryoun Kim
Korean J Intern Med. 2015;30(1):96-103. Published online December 30, 2014
Background/Aims: Respiratory viruses (RVs) are considered to be important respiratory pathogens in adult patients, and the multiplex reverse transcription-polymerase chain reaction (RT-PCR) test is used frequently in adult patients with respiratory infections. However, clinical data regarding utiliz..
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Gastroenterology / Original Article
Clinicopathological characteristics of synchronous and metachronous gastric neoplasms after endoscopic submucosal dissection
Mi Young Jang, Jin Woong Cho, Wang Guk Oh, Sung Jun Ko, Shang Hoon Han, Hoon Ki Baek, Young Jae Lee, Ji Woong Kim, Gum Mo Jung, Yong Keun Cho
Korean J Intern Med. 2013;28(6):687-693. Published online October 29, 2013
Background/AimsEndoscopic submucosal dissection (ESD) has become accepted as a minimally invasive treatment for gastric neoplasms. However, the development of synchronous or metachronous gastric lesions after endoscopic resection has become a major problem. We investigated the..
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Hemato-oncology / Review
Diagnosis and therapy of multiple myeloma
Antonio Palumbo, Chiara Cerrato
Korean J Intern Med. 2013;28(3):263-273. Published online May 1, 2013
Many advances in the treatment of multiple myeloma have been made due to the use of transplantation and the introduction of novel agents including thalidomide, lenalidomide, and bortezomib. The first step is recognizing the symptoms and starting prompt treatment. Different strategies should be se..
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Case Report
A case of secondary syphilis presenting as multiple pulmonary nodules
Se Joong Kim, Ju-Han Lee, Eung-Seok Lee, Il-Hwan Kim, Hyung Joo Park, Chol Shin, Je Hyeong Kim
Korean J Intern Med. 2013;28(2):231-235. Published online February 27, 2013
Syphilis is a sexually transmitted disease caused by Treponema pallidum. The prevalence of this disease has recently increased worldwide. However, pulmonary involvement in secondary syphilis is extremely rare. A 51-year-old heterosexual male patient presented with multiple pulmon..
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Letter to the editor
Primary Pulmonary Plasmacytoma Presenting as Multiple Lung Nodules
Sang-Heon Kim, Tae Hyung Kim, Jang Won Sohn, Ho Joo Yoon, Dong Ho Shin, In Soon Kim, Sung Soo Park
Korean J Intern Med. 2012;27(1):111-113. Published online February 28, 2012
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Original Article
A Combination of Melphalan, Prednisone, and 50 mg Thalidomide Treatment in Non-Transplant-Candidate Patients with Newly Diagnosed Multiple Myeloma
Hye Jung Chang, Jae Hoon Lee, Young Rok Do, Sung-Hwa Bae, Jung-Lim Lee, Seung Hyun Nam, Sung-Soo Yoon, Soo-Mee Bang
Korean J Intern Med. 2011;26(4):403-409. Published online November 28, 2011
Background/AimsThe clinical efficacy and safety of a three-drug combination of melphalan, prednisone, and thalidomide were assessed in patients with multiple myeloma who were not candidates for high-dose therapy as a first-line treatment. Because the side effects of thalidomid..
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Original Article
Predictive Value of Post-Transplant Bone Marrow Plasma Cell Percent in Multiple Myeloma Patients Undergone Autologous Transplantation
In Hye Hwang, Joo Seop Chung, Ho Jin Shin, Young Jin Choi, Moo Kon Song, Young Mi Seol, Goon Jae Cho, Bo Gwang Choi, Mun Ki Choi, Bo Kyung Choi, Kang Hee Ahn, Kyung Hwa Shin, Hee Sun Lee, Hyung Seok Nam, Jong Min Hwang
Korean J Intern Med. 2011;26(1):76-81. Published online March 2, 2011
Background/AimsAutologous stem cell transplantation (ASCT) has become the treatment of choice for patients with multiple myeloma (MM). Studies have shown that maintenance treatment with interferon-alpha is associated with improved survival rates following ASCT. However, despit..
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Case Report
Thalidomide Induced Nonspecific Interstitial Pneumonia in Patient with Relapsed Multiple Myeloma
Myung-Hee Kang, Ji-Hyun Ju, Hoon-Gu Kim, Jung Hun Kang, Kyung-Nyeo Jeon, Ho-Cheol Kim, Gyeong-Won Lee
Korean J Intern Med. 2010;25(4):447-449. Published online November 27, 2010
A 63-year-old female diagnosed with relapsed multiple myeloma visited our hospital complaining of a persistent cough. Since July 2006, she had been taking 100 mg thalidomide daily and gradually developed shortness of breath and a persistent dry cough. A chest X-ray and computed tomography showed ..
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Case Report
Two Lung Masses with Different Responses to Pemetrexed
Kwang Young Park, Jae Wook Jung, Seung Bum Nam, Ho Jin Lee, Hyo Seok Kim, Yoon Hee Choi, Jae Cheol Lee
Korean J Intern Med. 2010;25(2):213-216. Published online June 1, 2010
We described here a patient who had two lung masses. Although the two masses had the same histology and a similar good response to initial chemotherapy with gemcitabine and carboplatin, the response to pemetrexed as a second-line treatment was different after re-growth of the tumors. These two lu..
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Original Article
Elevation of Serum Ferritin is Associated with the Outcome of Patients with Newly Diagnosed Multiple Myeloma
Moo-Kon Song, Joo-Seop Chung, Young-Mi Seol, Ho-Jin Shin, Young-Jin Choi, Goon-Jae Cho
Korean J Intern Med. 2009;24(4):368-373. Published online November 27, 2009
Background/AimsSerum ferritin is a marker of acute phase reactions and iron storage. In addition, hematologic malignancies are associated with elevated serum ferritin levels. Other studies have suggested that ferritin is a surrogate for advanced disease and has an impact on re..
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Case Report
A Case of Nonsecretory Multiple Myeloma with Atypical Imaging Features
Hwa Yeon Lee, Seung Min Yoo, In Sup Song, Hyeon Yu, Jong Beum Lee, Jong Wook Shin, In Won Park
Korean J Intern Med. 2006;21(3):202-205. Published online September 30, 2006
Multiple myeloma usually shows homogeneous enhancement on contrast-enhanced Magnetic Resonance imaging (MRI), and is accompanied by a monoclonal gammopathy in serum or urine. We report a case of nonsecretory myeloma, the diagnosis was difficult due to the absence of a monoclonal gammopathy and th..
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Original Article
Double Autologous Stem Cell Transplantation for Multiple Myeloma: A Korean Single Center Study
Ock Bae Ko, Shin Kim, Hyeok Shim, Jung-Hun Lee, Jung-Min Ahn, Soon-Man Yoon, Min-Hyok Jeon, Il-No Do, So-young Lee, Yong Gil Kim, Sang We Kim, Sung-Bae Kim, Sang-Hee Kim, Jung Shin Lee, Wookun Kim, Chan-Jung Park, Hyun-sook Chi, Cheolwon Suh
Korean J Intern Med. 2005;20(3):237-242. Published online September 30, 2005
BackgroundAlthough high dose chemotherapy coupled with an autologous stem cell transplantation (ASCT) is widely accepted as effective therapy for multiple myeloma (MM), few reports are available in Korea, especially in the area of double ASCT. We present the results of an inst..
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