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Endocrinology-metabolism
Avoiding or coping with severe hypoglycemia in patients with type 2 diabetes
Jae-Seung Yun, Seung-Hyun Ko
Korean J Intern Med. 2015;30(1):6-16. Published online December 30, 2014
Hypoglycemia is a major barrier to achieving the glycemic goal in patients with type 2 diabetes. In particular, severe hypoglycemia, which is defined as an event that requires the assistance of another person to actively administer carbohydrates, glucagon, or take other corrective actions, is a seri..
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Molecular Mechanism of Insulin Resistance in Obesity and Type 2 Diabetes
Kangduk Choi, Young-Bum Kim
Korean J Intern Med. 2010;25(2):119-129. Published online June 1, 2010
Insulin resistance is a major risk factor for developing type 2 diabetes caused by the inability of insulin-target tissues to respond properly to insulin, and contributes to the morbidity of obesity. Insulin action involves a series of signaling cascades initiated by insulin binding to its recept..
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Hepatocyte nuclear factor 1-alpha mutation in normal glucose-tolerant subjects and early-onset type 2 diabetic patients
Dong Mee Lim, Nam Huh, Keun Yong Park
Korean J Intern Med. 2008;23(4):165-169. Published online December 29, 2008
Background/AimsThe prevalence of diabetes in Korea is reported to be approximately 10%, but cases of maturity-onset diabetes of the young (MODY) are rare in Korea. A diagnostic technique for autosomal dominant MODY is being actively sought. In this regard, we used a DNA chip t..
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Flexible Initial Dosing of Atorvastatin Based Upon Initial Low-Density Lipoprotein Cholesterol Levels in Type 2 Diabetic Patients
Korean J Intern Med. 2008;23(1):22-29. Published online March 20, 2008
Background/AimsWe used flexible starting doses and early titration of atorvastatin to determine the rate of achievement of a low-density lipoprotein cholesterol (LDL-C) target for hyperlipidemic patients with type 2 diabetes mellitus. Me.. </div>
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