Prostaglandin D2 and TH2 Inflammation in the Pathogenesis of Bronchial Asthma
Masafumi Arima, Takeshi Fukuda
Korean J Intern Med. 2011;26(1):8-18. Published online March 2, 2011
Prostaglandin D2 (PGD2) is a major prostanoid, produced mainly by mast cells, in allergic diseases, including bronchial asthma. PGD2-induced vasodilatation and increased permeability are well-known classical effects that may be involved in allergic inflammation. R..
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