Rheumatology
CRISPR-Cas9: a promising tool for gene editing on induced pluripotent stem cells
Eun Ji Kim, Ki Ho Kang, Ji Hyeon Ju
Korean J Intern Med. 2017;32(1):42-61. Published online January 1, 2017
Recent advances in genome editing with programmable nucleases have opened up new avenues for multiple applications, from basic research to clinical therapy. The ease of use of the technology—and particularly clustered regularly interspaced short palindromic repeats (CRISPR)—will allow us to impro..
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