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Cardiology / Original Article
Association of the triglyceride-glucose index with cardiovascular outcomes across cardiovascular-kidney-metabolic syndrome stages
Byung Sik Kim, Hyun-Jin Kim, Shinje Moon, Hasung Kim, Jungkuk Lee, Jeong-Hun Shin
Korean J Intern Med. 2025;40(6):961-974. Published online October 31, 2025
Background/Aims: Cardiovascular-kidney-metabolic (CKM) syndrome reflects the interplay between metabolic dysfunction, chronic kidney disease, and cardiovascular disease. Insulin resistance (IR) is a key driver of CKM and is associated with adverse cardiovascular outcomes. The triglyceride-glucose (T..
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Endocrinology-metabolism / Original Article
Association between body mass index and survival after hematopoietic stem cell transplantation
Han-Sang Baek, Jong Hyuk Lee, Joonyub Lee, Seung-Hwan Lee, Gi June Min, Sung-Soo Park, Silvia Park, Sung-Eun Lee, Byung-Sik Cho, Ki-Seong Eom, Yoo-Jin Kim, Seok Lee, Hee-Je Kim, Chang-Ki Min, Seok-Goo Cho, Jong Wook Lee, Jae-Ho Yoon
Korean J Intern Med. 2025;40(4):645-656. Published online July 1, 2025
Background/Aims: The unclear relationship between body mass index (BMI) and post-hematopoietic stem cell transplantation (HSCT) mortality was investigated, including the impact of metabolic diseases.
Methods: This retrospective study conducted at a Korean tertiary hospital (2009–2021) included patie..
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Gastroenterology / Original Article
Impact of body mass index on clinical outcomes in intestinal Behçet’s disease
Daye Park, Jihye Park, Soo Jung Park, Jae Jun Park, Tae Il Kim, Jae Hee Cheon
Korean J Intern Med. 2025;40(4):606-615. Published online July 1, 2025
Background/Aims: The impact of body mass index (BMI) on the clinical outcomes of intestinal Behçet’s disease (BD) remains unclear. This study assessed the association between BMI and disease progression.
Methods: A retrospective analysis of 760 patients with intestinal BD was conducted. Patients were..
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Cardiology / Original Article
Fact sheet: nationwide trends in dietary intakes among Korean adults, 2013-2022
Hannah Oh, Garam Jo, Oh Yoen Kim, Hyunjung Lim, SuJin Song, Jeong-Hwa Choi, Jae Hyun Bae, Eun-Sun Jin, Rockli Kim, Yujin Lee, In-Kyung Jeong, Min-Jeong Shin; on Behalf of the Committee of Nutrition and Public Relation of the Korean Society of Lipid and Atherosclerosis
Korean J Intern Med. 2025;40(3):427-437. Published online March 25, 2025
Background/Aims: Cardiovascular disease is the leading cause of death worldwide. This study aimed to investigate the recent nationwide trends in major dietary risk factors for dyslipidemia and atherosclerosis.
Methods: We estimated age-standardized mean intakes of fresh fruits, fresh vegetables, wh..
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Endocrinology-metabolism / Original Article
Persistent influence of past obesity on current adiponectin levels and mortality in patients with type 2 diabetes
Min-Ji Kim, Sung-Woo Kim, Bitna Ha, Hyang Sook Kim, So-Hee Kwon, Jonghwa Jin, Yeon-Kyung Choi, Keun-Gyu Park, Jung Guk Kim, In-Kyu Lee, Jae-Han Jeon
Korean J Intern Med. 2025;40(2):299-309. Published online March 1, 2025
Background/Aims: Adiponectin, a hormone primarily produced by adipocytes, typically shows an inverse relationship with body mass index (BMI). However, some studies have reported a positive correlation between the two. Thus, this study aimed to examine the relationship between adiponectin level and B..
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Nephrology / Original Article
Obesity is associated with incident chronic kidney disease in individuals with normal renal function
Su Hyun Song, Tae Ryom Oh, Sang Heon Suh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Soo Wan Kim, Eun Hui Bae
Korean J Intern Med. 2024;39(5):813-822. Published online August 13, 2024
Background/Aims: Obesity has known to be a modifiable risk factor associated with worse outcomes in chronic kidney disease (CKD), but few studies have examined the impact of obesity on CKD incidence in the general population. The purpose of this study was to investigate the role of body mass index (..
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Cardiology / Original Article
Influence of an abnormal ankle-brachial index on ischemic and bleeding events in patients undergoing percutaneous coronary intervention
Hangyul Kim, Seung Do Lee, Hyo Jin Lee, Hye Ree Kim, Kyehwan Kim, Jin-Sin Koh, Seok-Jae Hwang, Jin-Yong Hwang, Jong-Hwa Ahn, Yongwhi Park, Young-Hoon Jeong, Jeong Rang Park, Min Gyu Kang
Korean J Intern Med. 2023;38(3):372-381. Published online April 20, 2023
Background/Aims: Bleeding events after percutaneous coronary intervention (PCI) have important prognostic implications. Data on the influence of an abnormal ankle-brachial index (ABI) on both ischemic and bleeding events in patients undergoing PCI are limited.
Methods: We included patients who unde..
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Pulmonology / Original Article
Timing of corticosteroids in non-severe non-hospitalized COVID-19 patients: open-label, two-center, randomized controlled study (TICS-COV19 study)
Emad R. Issak, Mariam M. Amin
Korean J Intern Med. 2023;38(2):207-217. Published online January 17, 2023
Background/Aims: Corticosteroids (CSs) are frequently used in coronavirus disease 2019 (COVID-19); however, their utility remains controversial in mild to moderate cases. The timing of CSs initiation during the disease course remains unaddressed. The study aims to evaluate the impact of early CSs in..
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Allergy / Original Article
The burden of symptomatic patients with chronic spontaneous urticaria: a real-world study in Korea
Young-Min Ye, Young-Il Koh, Jeong-Hee Choi, Mi-Ae Kim, Jung-Won Park, Tae-Bum Kim, Young-Hee Nam, Yoon-Seok Chang, Hae-Sim Park
Korean J Intern Med. 2022;37(5):1050-1060. Published online September 1, 2022
Background/Aims: Chronic spontaneous urticaria (CSU) poses a considerable burden both on the quality of life (QoL) of individual patients and on healthcare systems. Real‑world data evaluating the disease burden of CSU are limited in this country. This study evaluated the disease burden and healthc..
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Nephrology / Original Article
Low waist circumference prior to percutaneous coronary intervention predict the risk for end-stage renal disease: a nationwide Korean population based-cohort study
Eun Hui Bae, Sang Yup Lim, Eun Mi Yang, Tae Ryom Oh, Hong Sang Choi, Chang Seong Kim, Seong Kwon Ma, Bongseong Kim, Kyung-Do Han, Soo Wan Kim
Korean J Intern Med. 2022;37(3):639-652. Published online February 11, 2022
Background/Aims: The obesity paradox has been known in end-stage renal disease (ESRD). However, the effect of body mass index (BMI) or waist circumference (WC) prior to percutaneous coronary intervention (PCI) on the development of ESRD is not clear.
Methods: Using nationally representative data fr..
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Cardiology / Original Article
Reference diameter and characteristics of the distal radial artery based on ultrasonographic assessment
Jun-Won Lee, Jung-Woo Son, Tae-Hwa Go, Dae Ryong Kang, Sang Jun Lee, Se Eun Kim, Dong-Hyuk Cho, Young Jun Park, Young Jin Youn, Min-Soo Ahn, Sung Gyun Ahn, Jang-Young Kim, Byung-Su Yoo, Junghan Yoon, Seung-Hwan Lee
Korean J Intern Med. 2022;37(1):109-118. Published online December 29, 2021
Background/Aims: While distal radial artery (DRA) access is increasingly being used for diagnostic coronary angiography, limited information is available regarding DRA size. We aimed to determine the DRA reference diameters of Korean patients and identify the predictors of DRA diameter < 2.3 mm.
Me..
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Rheumatology / Original Article
Association of body composition with disease activity and disability in rheumatoid arthritis
Kyeong Min Son, Seong Hun Kang, Young Il Seo, Hyun Ah Kim
Korean J Intern Med. 2021;36(1):214-222. Published online May 15, 2020
Background/Aims: To explore the associations between body composition and pain, disease activity, and disability in rheumatoid arthritis (RA).
Methods: The study enrolled 335 patients with RA and underwent body composition measurement with an InBody analyzer. The associations of body mass index (BM..
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Endocrinology-metabolism / Original Article
Optimal body mass index for minimizing the risk for osteoporosis and type 2 diabetes
Ji Hyun Lee, Jung Hee Kim, A Ram Hong, Sang Wan Kim, Chan Soo Shin
Korean J Intern Med. 2020;35(6):1432-1442. Published online October 30, 2019
Background/Aims: Body mass index (BMI) is positively associated with bone mineral density and type 2 diabetes. We investigated an optimal BMI range for osteoporosis and type 2 diabetes.
Methods: This cross-sectional study used data from the Korea National Health and Nutrition Examination Survey (KN..
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Rheumatology / Original Article
Impact of sleep quality on clinical features of primary Sjögren's syndrome
Sang Wan Chung, Jaehyung Hur, You-Jung Ha, Eun Ha Kang, Joon Young Hyon, Hyo-Jung Lee, Yeong Wook Song, Yun Jong Lee
Korean J Intern Med. 2019;34(5):1154-1164. Published online February 20, 2018
Background/Aims: This study aimed to investigate the inf luence of poor sleep quality on clinical features of primary Sjögren’s syndrome (pSS).
Methods: Sleep quality was cross-sectionally assessed using the Pittsburgh Sleep Quality Index (PSQI), and demographic, clinical, and laboratory data we..
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Rheumatology / Original Article
Characteristics of hip involvement in patients with ankylosing spondylitis in Korea
Hyemin Jeong, Yeong Hee Eun, In Young Kim, Hyungjin Kim, Jaejoon Lee, Eun-Mi Koh, Hoon-Suk Cha
Korean J Intern Med. 2017;32(1):158-164. Published online March 25, 2016
Background/Aims: To evaluate the clinical course of hip arthritis and the risk factors for hip joint replacement in patients with ankylosing spondylitis (AS). Methods: In this retrospective analysis, we evaluated 488 AS patients at a single tertiary hospital. At baseline and the most recent visit to..
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Endocrinology-metabolism / Review
Differences among skeletal muscle mass indices derived from height-, weight-, and body mass index-adjusted models in assessing sarcopenia
Kyoung Min Kim, Hak Chul Jang, Soo Lim
Korean J Intern Med. 2016;31(4):643-650. Published online June 22, 2016
Aging processes are inevitably accompanied by structural and functional changes in vital organs. Skeletal muscle, which accounts for 40% of total body weight, deteriorates quantitatively and qualitatively with aging. Skeletal muscle is known to play diverse crucial physical and metabolic roles in hu..
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Hemato-oncology / Original Article
Treatment outcomes and clinical relevance of the
Follicular Lymphoma International Prognostic Index in Korean follicular lymphoma patients
treated with chemotherapy
Chi Hoon Maeng, Sung Woo Ahn, Seong-Yoon Ryu, Sungjun Han, Young Hyeh Ko, Jun Ho Ji, Won Seog Kim, Seok Jin Kim
Korean J Intern Med. 2016;31(3):560-569. Published online February 22, 2016
Background/Aims: The Follicular Lymphoma International Prognostic Index (FLIPI) and FLIPI2 are well-known prognostic models for patients with follicular lymphoma (FL). However, their prognostic relevance has not been examined before in Korean patients with FL.
Methods: We reviewed clinical and labo..
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Gastroenterology / Original Article
Diagnostic value of alcoholic liver disease (ALD)/nonalcoholic fatty liver disease (NAFLD) index combined with γ-glutamyl transferase in differentiating ALD and NAFLD
Junling Wang, Ping Li, Zhilong Jiang, Qiuhui Yang, Yuqiang Mi, Yonggang Liu, Ruifang Shi, Yonghe Zhou, Jinsheng Wang, Wei Lu, Si Li, Dan Liu
Korean J Intern Med. 2016;31(3):479-487. Published online March 30, 2016
Background/Aims: This study aimed to verify the reliability of the alcoholic liver disease (ALD)/nonalcoholic fatty liver disease (NAFLD) index (ANI) for distinguishing ALD in patients with hepatic steatosis from NAFLD, and to investigate whether ANI combined with γ-glutamyl transferase (GGT) woul..
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Rheumatology / Original Article
Validation and reliability of a Behcet’s Syndrome Activity Scale in Korea
Hyo Jin Choi, Mi Ryoung Seo, Hee Jung Ryu, Han Joo Baek
Korean J Intern Med. 2016;31(1):170-175. Published online December 28, 2015
Background/Aims: We prepared a cross-cultural adaptation of the Behcet’s Syndrome Activity Scale (BSAS) and evaluated its reliability and validity in Korea.
Methods: Fifty patients with Behcet’s disease (BD) who attended the Rheumatology Clinic of Gachon University Gil Medical Center were include..
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Nephrology / Original Article
Impact of dialysis modality on technique survival in end-stage renal disease patients
Jong-Hak Lee, Sun-Hee Park, Jeong-Hoon Lim, Young-Jae Park, Sang Un Kim, Kyung-Hee Lee, Kyung-Hoon Kim, Seung Chan Park, Hee-Yeon Jung, Owen Kwon, Ji-Young Choi, Jang-Hee Cho, Chan-Duck Kim, Yong-Lim Kim
Korean J Intern Med. 2016;31(1):106-115. Published online December 28, 2015
Background/Aims: This study analyzed the risk factors for technique survival in dialysis patients and compared technique survival rates between hemodialysis (HD) and peritoneal dialysis (PD) in a prospective cohort of Korean patients.
Methods: A total of 1,042 patients undergoing dialysis from Sept..
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