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Nephrology
Effect of low-dose valsartan on proteinuria in normotensive immunoglobulin A nephropathy with minimal proteinuria: a randomized trial
Young-Il Jo, Ha-Young Na, Ju-Young Moon, Sang-Woong Han, Dong-Ho Yang, Sang-Ho Lee, Hyeong-Cheon Park, Hoon-Young Choi, So-Dug Lim, Jeong-Hae Kie, Yong-Kyu Lee, Sug-Kyun Shin
Korean J Intern Med. 2016;31(2):335-343. Published online February 15, 2016
Background/Aims: Immunoglobulin A nephropathy (IgAN) is a generally progressive disease, even in patients with favorable prognostic features. In this study, we aimed to investigate the antiproteinuric effect and tolerability of low-dose valsartan (an angiotensin II receptor blocker) therapy in normo..
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Co-existing proteinase 3-antineutrophil cytoplasmic antibody-associated vasculitis with immunoglobulin A nephropathy
Adem Kucuk, Yalcin Solak, Abduzhappar Gaipov, Sinan Bagcaci, Hasan Esen, Suleyman Turk, Recep Tunc
Korean J Intern Med. 2016;31(1):194-196. Published online December 28, 2015
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Nephrology
High serum and urine neutrophil gelatinase-associated lipocalin levels are independent predictors of renal progression in patients with immunoglobulin A nephropathy
Harin Rhee, Nari Shin, Min Ji Shin, Byung Yun Yang, Il Young Kim, Sang Heon Song, Dong Won Lee, Soo Bong Lee, Ihm Soo Kwak, Eun Young Seong
Korean J Intern Med. 2015;30(3):354-361. Published online April 29, 2015
Background/Aims: Tubulointerstitial injury plays an important role in the progression of immunoglobulin A nephropathy (IgAN), and neutrophil gelatinase-associated lipocalin (NGAL) is among the most sensitive tubular biomarkers. We investigated whether serum or urine NGAL predicts prognosis in patien..
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Plasma neutrophil gelatinase-associated lipocalin as a potential predictor of adverse renal outcomes in immunoglobulin A nephropathy
Ga-Young Park, Chung-Hoon Yu, Jun-Seop Kim, Yun-Jeong Kang, Owen Kwon, Ji-Young Choi, Jang-Hee Cho, Chan-Duck Kim, Yong-Lim Kim, Sun-Hee Park
Korean J Intern Med. 2015;30(3):345-353. Published online April 29, 2015
Background/Aims: Neutrophil gelatinase-associated lipocalin (NGAL) is a well-known biomarker of acute kidney injury. We evaluated the value of plasma NGAL (pNGAL) as an independent predictor of prognosis in immunoglobulin A nephropathy (IgAN).
Methods: In total, 91 patients with biopsy-proven IgAN ..
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Urinary excretion of β2-microglobulin as a prognostic marker in immunoglobulin A nephropathy
Jae Ryung Shin, Seung Min Kim, Jung Sun Yoo, Ji Yoon Park, Seul Ki Kim, Joo Hee Cho, Kyung Hwan Jeong, Tae Won Lee, Chun Gyoo Ihm
Korean J Intern Med. 2014;29(3):334-340. Published online April 29, 2014
Background/Aims: β2-microglobulin (β2-MG) is freely filtered at the glomerulus and subsequently reabsorbed and catabolized by proximal renal tubular cells. Urinary β2-MG is an early and sensitive biomarker of acute kidney injury; however, its utility as a bio..
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Urokinase, urokinase receptor, and plasminogen activator inhibitor-1 expression on podocytes in immunoglobulin A glomerulonephritis
Ji-Hye Lee, Mee-Hye Oh, Jae-Seok Park, Gyoung-Jae Na, Hye-Wook Gil, Jong-Oh Yang, Eun-Young Lee, Sae-Yong Hong
Korean J Intern Med. 2014;29(2):176-182. Published online February 27, 2014
Background/Aims: The purpose of this study was to investigate the expression of urokinase-type plasminogen activator (uPA), uPA receptor (uPAR), and plasminogen activator inhibitor (PAI)-1 on podocytes in immunoglobulin A (IgA) glomerulonephritis (GN).
Methods: Renal biopsy specimens from 52 IgA G..
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