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Sarcopenia in chronic kidney disease: from bench to bedside
Da Woon Kim, Sang Heon Song
Korean J Intern Med. 2023;38(3):303-321. Published online April 20, 2023
Sarcopenia is a condition characterized by a loss of muscle mass and function. In chronic kidney disease (CKD), where a chronic catabolic state exists, sarcopenia commonly occurs through various mechanisms, resulting in muscle wasting and decreased muscle endurance. Sarcopenic patients with CKD have..
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Management of inflammatory bowel disease beyond tumor necrosis factor inhibitors: novel biologics and small-molecule drugs
Soo-Young Na, You Sun Kim
Korean J Intern Med. 2022;37(5):906-919. Published online August 10, 2022
The incidence and prevalence of inflammatory bowel disease (IBD), comprising Crohn’s disease and ulcerative colitis, have increased in Asia and developing countries. In the past two decades, anti-tumor necrosis factor (TNF) agents have revolutionized the treatment of IBD, in part by decreasing the..
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The use of biological disease-modifying antirheumatic drugs for inflammatory arthritis in Korea: results of a Korean Expert Consensus
Eun-Jung Park, Hyungjin Kim, Seung Min Jung, Yoon-Kyoung Sung, Han Joo Baek, Jisoo Lee
Korean J Intern Med. 2020;35(1):41-59. Published online January 2, 2020
Biological disease-modifying antirheumatic drugs (bDMARDs) are highly effective agents for the treatment of inf lammatory arthritis; however, they also possess a potential risk for serious infection. Recently, with the rapid expansion of the bDMARDs market in Korea, reports of serious adverse events ..
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Hemato-oncology
Neuropathic cancer pain: prevalence, pathophysiology, and management
So Young Yoon, Jeeyoung Oh
Korean J Intern Med. 2018;33(6):1058-1069. Published online June 25, 2018
Neuropathic cancer pain (NCP) is caused by nerve damage attributable to the cancer per se, and/or treatments including chemotherapy, radiotherapy, and surgery; the prevalence is reported to be as high as 40%. The etiologies of NCP include direct nerve invasion or nerve compression by the cancer, neu..
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Effects of Add-On Therapy with NDC-052, an Extract from Magnoliae Flos, in Adult Asthmatic Patients Receiving Inhaled Corticosteroids
Chan Sun Park, Tae-Bum Kim, Jae-Young Lee, Jae Yong Park, Yong Chul Lee, Seong Su Jeong, Yang Deok Lee, You Sook Cho, Hee-Bom Moon
Korean J Intern Med. 2012;27(1):84-90. Published online February 28, 2012
Background/AimsThere is a need for new anti-asthmatic medications with fewer side effects. NDC-052, an extract of the medicinal herb Magnoliae flos, which has a long history of clinical use, was recently found to have anti-inflammatory effects. Herein, we eval..
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The Impact of Generic Clopidogrel Bisulfate on Platelet Inhibition in Patients with Coronary Artery Stents: Results of the ACCEL-GENERIC Study
Young-Hoon Jeong, Jin-Sin Koh, Min-Kyung Kang, Yeon-Jeong Ahn, In-Suk Kim, Yongwhi Park, Seok-Jae Hwang, Choong Hwan Kwak, Jin-Yong Hwang
Korean J Intern Med. 2010;25(2):154-161. Published online June 1, 2010
Background/AimsIn patients with coronary artery stents, the cost of clopidogrel has been cited as a factor in the premature discontinuation of therapy. Thus, the introduction of lower-cost generic clopidogrel may increase patient compliance. However, platelet inhibition by ge..
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