Hemato-oncology
Mutations in genes affecting DNA methylation enhances responses to decitabine in patients with myelodysplastic syndrome
Hyun Ae Jung, Chul Won Jung, Jun Ho Jang
Korean J Intern Med. 2021;36(2):413-423. Published online October 23, 2020
Background/Aims: In this study, we tested whether mutations in the methylation pathway genes ten-eleven-translocation 2 (TET2) and DNA methyltransferase gene 3A (DNMT3A) improve the responses of patients with myelodysplastic syndrome (MDS) to decitabine.
Methods: We retrospectively se..
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