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Emotional and cognitive changes in chronic kidney disease
Duk-Soo Kim, Seong-Wook Kim, Hyo-Wook Gil
Korean J Intern Med. 2022;37(3):489-501. Published online March 8, 2022
Chronic kidney disease (CKD) leads to cognitive impairment and emotional changes. However, the precise mechanism underlying the crosstalk between the kidneys and the nervous system is not fully understood. Inflammation and cerebrovascular disease can influence the development of depression in CKD. C..
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Hemato-oncology
The efficacy of EGFR-tyrosine kinase inhibitor in non-small cell lung cancer patients with synchronous brain metastasis: a real-world study
Jin-Hyuk Choi, Yong Won Choi, Hyun Woo Lee, Seok Yun Kang, Geum Sook Jeong, Mi Sun Ahn, Young-Taek Oh, O kyu Noh, Se-Hyuk Kim, Tae Hoon Roh, Seung Soo Sheen
Korean J Intern Med. 2022;37(2):434-443. Published online February 16, 2022
Background/Aims: The optimal treatment (Tx) for epidermal growth factor receptor (EGFR)-mutant non-small cell lung cancer (NSCLC) patients with brain metastasis (BM) remains to be determined.
Methods: A retrospective review was conducted on 77 NSCLC patients with synchronous BM who underwent first-..
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Gastroenterology
Impact of non-hepatic hyperammonemia on mortality in intensive care unit patients: a retrospective cohort study
Jae Heon Kim, Hankyu Jeon, Sang Soo Lee, I Re Heo, Jung Woo Choi, Hee Jin Kim, Ra Ri Cha, Jae Min Lee, Hyun Jin Kim
Korean J Intern Med. 2021;36(6):1347-1355. Published online July 15, 2021
Background/Aims: The effect of hyperammonemia on the mortality in patients with liver cirrhosis is well documented. However, little is known about the impact of hyperammonemia on mortality among intensive care unit patients without hepatic disease. We aimed to investigate factors associated with non..
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Hemato-oncology
The prognostic factors influencing overall survival in uterine cervical cancer with brain metastasis
Hyera Kim, Kang Kook Lee, Mi Hwa Heo, Jin Young Kim
Korean J Intern Med. 2019;34(6):1324-1332. Published online October 26, 2018
Background/Aims: The occurrence of brain metastasis (BM) has increased due to improved overall survival (OS) in uterine cervical cancer. However, research about prognostic factors and therapeutic guidelines for BM in uterine cervical cancer remains scarce due to the rarity of BM in this type of canc..
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Cardiology
Body fluid status assessment by bio-impedance analysis in patients presenting to the emergency department with dyspnea
Chan Soon Park, Sang-Eun Lee, Hyun-Jai Cho, Yong-Jin Kim, Hyun-Jae Kang, Byung-Hee Oh, Hae-Young Lee
Korean J Intern Med. 2018;33(5):911-921. Published online December 18, 2017
Background/Aims: Fluid retention occurs in patients with heart failure, accounting for dyspnea. We investigated the diagnostic implication of body fluid status, assessed by bio-impedance analysis (BIA), in acute heart failure (AHF) among patients who presented with dyspnea.
Methods: A total of 100 ..
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Hemato-oncology
Epidermal growth factor receptor mutation and pattern of brain metastasis in patients with non-small cell lung cancer
Min Young Baek, Hee Kyung Ahn, Kyu Ree Park, Hwa-Sun Park, Shin Myung Kang, Inkeun Park, Young Saing Kim, Junshik Hong, Sun Jin Sym, Jinny Park, Jae Hoon Lee, Dong Bok Shin, Eun Kyung Cho
Korean J Intern Med. 2018;33(1):168-175. Published online April 20, 2016
Background/Aims: We investigated the time taken for patients with metastatic non-small cell lung cancer (NSCLC) to develop brain metastases (BM), as well as their subsequent overall median survival following diagnosis, considering the epidermal growth factor receptor (EGFR) mutational status...
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Solitary bone and brain metastasis in a patient with papillary thyroid carcinoma mimicking cavernous angioma
Eugene Han, Ye Yeon Lee, El Kim, Sun Young Kwon, Sang Pyo Kim, Hye Soon Kim, Mi Kyung Kim
Korean J Intern Med. 2016;31(5):991-994. Published online January 27, 2016
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Relationship between serum brain natriuretic peptide and heart function in patients with chronic kidney disease
Jae Won Yang, Min Soo Kim, Jae Seok Kim, Jong Myoung Yoo, Seung Tae Han, Bi Ro Kim, Yun Deok Kim, Jeong Wook Choi, Seung Ok Choi, Byoung Geun Han
Korean J Intern Med. 2008;23(4):191-200. Published online December 30, 2008
Background/AimsBrain natriuretic peptide (BNP) levels are known to be elevated in patients with chronic kidney disease (CKD) and normal heart function. Therefore, the present study was performed to examine the effectiveness of BNP level in diagnosing heart failure in patients ..
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N-terminal pro-B-type natriuretic peptide as a marker of disease severity in patients with pericardial effusions
Shin-Jae Kim, Eun-Seok Shin, Sang-Gon Lee
Korean J Intern Med. 2008;23(2):78-86. Published online June 20, 2008
Backgraound/AimsN-terminal pro-B-type natriuretic peptide (NT-proBNP) has recently been introduced as a useful marker in diagnosing underlying disease in patients with dyspnea and for determining the prognosis of patients with heart failure. The purpose of this study was to ev..
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Paroxysmal Autonomic Dysregulation with Fever that was Controlled by Propranolol in a Brain Neoplasm Patient
Su Jin Oh, Yun Kyung Hong, Eun-Kee Song
Korean J Intern Med. 2007;22(1):51-54. Published online March 31, 2007
Intractable fever in cancer patients is problematic and the causes of this fever can be diverse. Paroxysmal persistent hyperthermia after sudden mental change or neurologic deficit can develop via autonomic dysregulation without infection or any other causes of fever. Paroxysmal hyperthermic auto..
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