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Endocrinology-metabolism
The efficacy of denosumab in Korean male patients with osteoporosis
Chaiho Jeong, Jeonghoon Ha, Jinyoung Kim, Yejee Lim, Mee Kyoung Kim, Hyuk-Sang Kwon, Ki-Ho Song, Moo Il Kang, Ki-Hyun Baek
Korean J Intern Med. 2022;37(5):1011-1020. Published online June 3, 2022
Background/Aims: Despite the prominence of denosumab as the number one prescribed anti-osteoporosis drug in Korea, the effects of denosumab in male osteoporosis patients were not researched sufficiently. Moreover, concerns on rebound vertebral fractures associated with poor denosumab adherence exist..
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Benefits of lumican on human bone health: clinical evidence using bone marrow aspirates
Yun Sun Lee, So Jeong Park, Jin Young Lee, Eunah Choi, Beom-Jun Kim
Korean J Intern Med. 2022;37(4):821-829. Published online April 26, 2022
Background/Aims: Lumican, a small leucine-rich proteoglycan, has shown osteoprotective effects by synchronously stimulating bone formation and suppressing bone resorption. To clarify the role of lumican in human bone metabolism, the association between lumican concentrations and osteoporosis-related..
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Pulmonology
Relationship between pulmonary function and bone mineral density in the Korean National Health and Nutrition Examination Survey
In Seon Lee, Ah Young Leem, Sang Hoon Lee, Yumie Rhee, Yoon Ha, Young Sam Kim
Korean J Intern Med. 2016;31(5):899-909. Published online September 1, 2016
Background/Aims: Osteoporosis is common in chronic obstructive pulmonary disease (COPD) patients. The relationship between osteoporosis and COPD has been primarily reported in patients with moderate to severe COPD, but there is no report in the general population. The aim of this study is to investi..
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Endocrinology-metabolism
Association between household size, residential area, and osteoporosis: analysis of 2008 to 2011 Korea National Health and Nutrition Examination Survey
Sung-Woo Kim, Kwi-Hyun Bae, Jung-Beom Seo, Jae-Han Jeon, Won-Kee Lee, In-Kyu Lee, Jung-Guk Kim, Keun-Gyu Park
Korean J Intern Med. 2016;31(4):712-721. Published online April 15, 2016
Background/Aims: The prevalence of single-person households has rapidly increased in Korea. Individuals living alone and in rural areas may have a higher risk of various metabolic diseases due to differences in lifestyle. However, few studies have investigated the association of household size and r..
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The Progression of Bone Mineral Density Loss in Dialysis Patients Compared with the General Population
Petar Avramovski, Aleksandar Sikole
Korean J Intern Med. 2012;27(4):436-442. Published online November 27, 2012
Background/AimsThe aim of this study was to compare the progression of bone mass loss in chronic hemodialysis patients (CHPs) with that in general population patients (GPPs) over an 18-month period. MethodsThe control group consisted of 60 patien..
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Effects of D-003 (10 mg/day) on Bone Mineral Density of the Lumbar Spine and Femoral Neck in Postmenopausal Women: A Randomized, Double-Blinded Study
Alfredo Ceballos, Gladys Castaño, Sarahí Mendoza, Juan González, Rosa Mas, Lilia Fernández, José Illnait, Meilis Mesa, Rafael Gámez, Julio César Fernández, Ricardo Telles, Duany Marrero, Mainel Gómez Eng, Dalmer Ruiz, Yunaisi Jardines
Korean J Intern Med. 2011;26(2):168-178. Published online June 1, 2011
Background/AimsIncreased osteoclast activity is a pivotal finding in osteoporosis. This increase is mediated via the mevalonate-to-cholesterol pathway, which is involved in producing the intermediates required for osteoclast activity. D-003, a mixture of high molecular weight ..
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