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Expanding the therapeutic landscape: ezetimibe as non-statin therapy for dyslipidemia
Jeongmin Lee, Seung-Hwan Lee
Korean J Intern Med. 2023;38(6):797-809. Published online October 20, 2023
Dyslipidemia is a significant risk factor for atherosclerotic cardiovascular disease (ASCVD), and statins are the primary therapeutic options for reducing low-density lipoprotein cholesterol (LDL-C) levels. However, it can be challenging to achieve optimal LDL-C goals with statin monotherapy. Ezetim..
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2022 Consensus statement on the management of familial hypercholesterolemia in Korea
Chan Joo Lee, Minjae Yoon, Hyun-Jae Kang, Byung Jin Kim, Sung Hee Choi, In-Kyung Jeong, Sang-Hak Lee; on behalf of Task Force Team for Familial Hypercholesterolemia; Korean Society of Lipid and Atherosclerosis
Korean J Intern Med. 2022;37(5):931-944. Published online July 27, 2022
Familial hypercholesterolemia (FH) is the most common monogenic disorder. Due to the marked elevation of cardiovascular risk, the early detection, diagnosis, and proper management of this disorder are critical. Herein, the 2022 Korean guidance on this disease is presented. Clinical features include ..
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Nephrology
Plasma oxalic acid and cardiovascular risk in end-stage renal disease patients: a prospective, observational cohort pilot study
Natalia Stepanova, Victoria Driianska, Lesya Korol, Lyudmyla Snisar, Larysa Lebed
Korean J Intern Med. 2022;37(1):167-178. Published online June 25, 2021
Background/Aims: It was hypothesized that oxalate might be strongly involved in atherogenesis and the inflammatory pathway that could result in an increased risk of cardiovascular disease (CVD) in end-stage renal disease (ESRD) patients. Therefore, this study aimed to address two primary research qu..
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Cardiology
Efficacy and safety of pitavastatins in patients with acute myocardial infarction: Livalo in Acute Myocardial Infarction Study (LAMIS) II
Young Joon Hong, Myung Ho Jeong, Jang Ho Bae, Seok Kyu Oh, Seung Woon Rha, Seung Ho Hur, Sung Yun Lee, Sang Wook Kim, Kwang Soo Cha, In Ho Chae, Tae Hoon Ahn, Kee Sik Kim
Korean J Intern Med. 2017;32(4):656-667. Published online June 16, 2017
Background/Aims: We evaluated the efficacy and safety and influence on glucose tolerance by different doses of pitavastatins in acute myocardial infarction (AMI) patients.
Methods: Consecutive 1,101 AMI patients who were enrolled in Livalo in Acute Myocardial Infarction Study (LAMIS)-II were random..
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Predictive value of CHADS2 score for cardiovascular events in patients with acute coronary syndrome and documented coronary artery disease
In Sook Kang, Wook Bum Pyun, Gil Ja Shin
Korean J Intern Med. 2016;31(1):73-81. Published online December 28, 2015
Background/Aims: The CHADS2 score, used to predict the risk of ischemic stroke in atrial fibrillation (AF) patients, has been reported recently to predict ischemic stroke in patients with coronary heart disease, regardless of the presence of AF. However, little data are available regardin..
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Usual Dose of Simvastatin Does Not Inhibit Plaque Progression and Lumen Loss at the Peri-Stent Reference Segments after Bare-Metal Stent Implantation: A Serial Intravascular Ultrasound Analysis
Young Joon Hong, Myung Ho Jeong, Yun Ha Choi, Eun Hye Ma, Jum Suk Ko, Min Goo Lee, Keun Ho Park, Doo Sun Sim, Nam Sik Yoon, Hyun Ju Youn, Kye Hun Kim, Hyung Wook Park, Ju Han Kim, Youngkeun Ahn, Jeong Gwan Cho, Jong Chun Park, Jung Chaee Kang
Korean J Intern Med. 2010;25(4):356-363. Published online November 27, 2010
Background/AimsThe aim of this study was to assess the effects of a usual dose of simvastatin (20 mg/day) on plaque regression and vascular remodeling at the peri-stent reference segments after bare-metal stent implantation. MethodsWe retrospect..
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An Increased Monocyte Count Predicts Coronary Artery Spasm in Patients with Resting Chest Pain and Insignificant Coronary Artery Stenosis
Kyeong Ho Yun, Seok Kyu Oh, Eun Mi Park, Hyun Jung Kim, Sung Hee Shin, Eun Mi Lee, Sang Jae Rhee, Nam Jin Yoo, Nam-Ho Kim, Jin-Won Jeong, Myung Ho Jeong
Korean J Intern Med. 2006;21(2):97-102. Published online June 30, 2006
BackgroundCoronary atherosclerosis with inflammation gives rise to coronary vasospasm in the patients with coronary vasospastic angina. We have postulated that the peripheral leukocyte count and the differential count are associated with vasospastic angina.
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