Hemato-oncology
Long-term follow-up results of cytarabine-containing chemotherapy for acute promyelocytic leukemia
Young Hoon Park, Dae-Young Kim, Yeung-Chul Mun, Eun Kyung Cho, Jae Hoon Lee, Deog-Yeon Jo, Inho Kim, Sung-Soo Yoon, Seon Yang Park, Byoungkook Kim, Soo-Mee Bang, Hawk Kim, Young Joo Min, Jae Hoo Park, Jong Jin Seo, Hyung Nam Moon, Moon Hee Lee, Chul Soo Kim, Won Sik Lee, So Young Chong, Doyeun Oh, Dae Young Zang, Kyung Hee Lee, Myung Soo Hyun, Heung Sik Kim, Sung-Hyun Kim, Hyukchan Kwon, Hyo Jin Kim, Kyung Tae Park, Sung Hwa Bae, Hun Mo Ryoo, Jung Hye Choi, Myung-Ju Ahn, Hwi-Joong Yoon, Sung-Hyun Nam, Bong-Seog Kim, Chu-Myong Seong
Korean J Intern Med. 2022;37(4):841-850. Published online June 28, 2022
Background/Aims: We evaluated the feasibility and long-term efficacy of the combination of cytarabine, idarubicin, and all-trans retinoic acid (ATRA) for treating patients with newly diagnosed acute promyelocytic leukemia (APL).
Methods: We included 87 patients with newly diagnosed acute myeloid l..
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Influence of creatinine levels on survival in patients with veno-occlusive disease treated with defibrotide
Seom Gim Kong, Je-Hwan Lee, Young Tak Lim, Ji Hyun Lee, Hyeon-Seok Eom, Hyewon Lee, Do Young Kim, Sung-Nam Lim, Sung-Soo Yoon, Sung-Yong Kim, Ho Sup Lee
Korean J Intern Med. 2022;37(1):179-189. Published online December 14, 2021
Background/Aims: Veno-occlusive disease/sinusoidal obstruction syndrome (VOD/SOS) is one of the most fatal complications of hematopoietic cell transplantation (HCT), and defibrotide is the only curative drug. We conducted this study to confirm the survival rate of VOD/SOS patients diagnosed in Korea..
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Leukemic stem cell phenotype is associated with mutational profile in acute myeloid leukemia
Heejoo Han, Ja Min Byun, Dong-Yeop Shin, Sung-Soo Yoon, Youngil Koh, Junshik Hong, Inho Kim, Chansup Lee, Hyeonjoo Yoo, Hongseok Yun, Man Jin Kim, Sung Im Cho, Moon-Woo Seong, Sung Sup Park
Korean J Intern Med. 2021;36(2):401-412. Published online August 20, 2020
Background/Aims: Understanding leukemic stem cell (LSC) is important for acute myeloid leukemia (AML) treatment. However, association of LSC with patient prognosis and genetic information in AML patients is unclear.
Methods: Here we investigated the associations between genetic information and the ..
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Strong association between herpes simplex virus-1 and chemotherapy-induced oral mucositis in patients with hematologic malignancies
Junshik Hong, Hee-Kyung Park, Suhyun Park, Ahreum Lee, Yeon-Hee Lee, Dong-Yeop Shin, Youngil Koh, Ji-Yeob Choi, Sung-Soo Yoon, Youngnim Choi, Inho Kim
Korean J Intern Med. 2020;35(5):1188-1198. Published online September 9, 2019
Background/Aims: A link between oral cavity infections and chemotherapy-induced oral mucositis (CIOM) in patients with hematological malignancies (HMs) undergoing intensive chemotherapy (IC) or hematopoietic stem cell transplantation (HSCT) has been suggested. However, conclusive data are lacking, a..
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Clinicopathological characteristics of extremely young Korean multiple myeloma patients: therapeutic implications
Junghoon Shin, Youngil Koh, Jeonghwan Youk, Miso Kim, Byung Soo Kim, Chul Won Choi, Hwa Jung Sung, Yong Park, Sung-Soo Yoon, Inho Kim
Korean J Intern Med. 2017;32(4):722-730. Published online June 26, 2017
Background/Aims: Although multiple myeloma (MM) is typically a disease of the elderly, a certain subset of extremely young patients exists. It is necessary to establish clinicopathological characteristics for this population.
Methods: We reviewed the medical records of MM patients whose age was 40 ..
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A rare case of Rosai-Dorfman disease without lymphadenopathy
Hyerim Ha, Ki Hwan Kim, Young Joon Ahn, Ji Hye Kim, Ji Eun Kim, Sung-Soo Yoon
Korean J Intern Med. 2016;31(4):802-804. Published online February 2, 2016
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A Combination of Melphalan, Prednisone, and 50 mg Thalidomide Treatment in Non-Transplant-Candidate Patients with Newly Diagnosed Multiple Myeloma
Hye Jung Chang, Jae Hoon Lee, Young Rok Do, Sung-Hwa Bae, Jung-Lim Lee, Seung Hyun Nam, Sung-Soo Yoon, Soo-Mee Bang
Korean J Intern Med. 2011;26(4):403-409. Published online November 28, 2011
Background/AimsThe clinical efficacy and safety of a three-drug combination of melphalan, prednisone, and thalidomide were assessed in patients with multiple myeloma who were not candidates for high-dose therapy as a first-line treatment. Because the side effects of thalidomid..
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Acute Lymphoblastic Leukemia in Elderly Patients: A Single Institution's Experience
Dong-Yeop Shin, Inho Kim, Ki-Hwan Kim, Younak Choi, Seung Hoon Beom, Yaewon Yang, Yoojoo Lim, Eunyoung Lee, June Koo Lee, Ji Yeon Kim, Hyun Kyung Kim, Sung-Soo Yoon, Dong Soon Lee, Seonyang Park, Byoung-Kook Kim
Korean J Intern Med. 2011;26(3):328-339. Published online September 13, 2011
Background/AimsWe investigated the clinical characteristics and prognosis of elderly patients with acute lymphoblastic leukemia (ALL). MethodsWe reviewed the clinical data, laboratory findings, bone marrow findings, and cytogenetic analysis of el..
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Cost Analysis of Iron-Related Complications in a Single Institute
Ki Hwan Kim, Jin Won Kim, Ji young Rhee, Min-Kyung Kim, Byung-Su Kim, Inho Kim, Soo-Mee Bang, Sung-Soo Yoon, Jong-Seok Lee, Kyou-Sup Han, Seonyang Park, Byoung Kook Kim
Korean J Intern Med. 2009;24(1):33-36. Published online March 6, 2009
Background/AimsThe financial burden of caring for iron-related complications (IRCs) is an emerging medical problem in Korea, as in Western countries. We produced a preliminary estimate of the costs of treating patients for IRCs. Methods<..
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Pneumatosis Intestinalis with Pneumoperitoneum Mimicking Intestinal Perforation in a Patient with Myelodysplastic Syndrome after Hematopoietic Stem Cell Transplantation
Bhumsuk Keam, Jeong-Hoon Lee, Myoung-Don Oh, Inho Kim, Sung-Soo Yoon, Byoung Kook Kim, Seonyang Park
Korean J Intern Med. 2007;22(1):40-44. Published online March 31, 2007
Pneumatosis intestinalis (PI) is an uncommon disorder characterized by an accumulation of gas in the bowel wall, and has been associated with a variety of disorders and procedures. We describe a 35-year-old man who undertook hematopoietic stem cell transplantation due to myelodysplastic syndrome...
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High-dose Versus Low-dose Cyclophosphamide in Combination with G-CSF for Peripheral Blood Progenitor Cell Mobilization
Jin Seok Ahn, Seonyang Park, Seock-Ah Im, Sung-Soo Yoon, Jong-Seok Lee, Byoung Kook Kim, Soo-Mee Bang, Eun Kyung Cho, Jae Hoon Lee, Chul Won Jung, Hugh Chul Kim, Chu Myung Seong, Moon Hee Lee, Chul Soo Kim, Keun Seok Lee, Jung Ae Lee, Myung-Ju Ahn
Korean J Intern Med. 2005;20(3):224-231. Published online September 30, 2005
BackgroundTo compare the mobilizing effects and toxicities of two different doses of cyclophosphamide (CY) plus lenograstim (glycosylated G-CSF), we performed a prospective randomized study by enrolling patients suffering with either high-risk Non-Hodgkin's lymphoma (NHL) or b..
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