Gastroenterology / Original Article
17β-Estradiol reduces inflammation and modulates antioxidant enzymes in colonic epithelial cells
Hee Jin Son, Nayoung Kim, Chin-Hee Song, Sun Min Lee, Ha-Na Lee, Young-Joon Surh
Korean J Intern Med. 2020;35(2):310-319. Published online October 22, 2018
Background/Aims: Estrogen is known to have protective effect in colorectal cancer development. The aims of this study are to investigate whether estradiol treatment reduces inflammation in CCD841CoN, a female human colonic epithelial cell line and to uncover underlying mechanisms of estradiol effects.
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