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Geriatrics
Optimal blood pressure target in the elderly: rationale and design of the HOW to Optimize eLDerly systolic Blood Pressure (HOWOLD-BP) trial
Dong-Hwa Lee, Ju-Hee Lee, So Young Kim, Hae-Young Lee, Jung-Yeon Choi, Youjin Hong, Sue K. Park, Dong Ryeol Ryu, Dong Heon Yang, Seok-Jae Hwang, Jung Hyun Choi, Kye Hun Kim, Sun Hwa Lee, Seung Jae Joo, Jae-Hyeong Park, Sang-Hyun Kim, Hack-Lyong Kim, Kwang-il Kim, Myeong-Chan Cho
Korean J Intern Med. 2022;37(5):1070-1081. Published online July 21, 2022
Background/Aims: The optimal systolic blood pressure (SBP) goal for elderly patients with hypertension, especially to reduce cardiovascular disease (CVD) incidence and improve outcome, is unclear. This study aimed to evaluate the beneficial effects of intensive treatment for hypertension on the inci..
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Cardiology
J-curve relationship between corrected QT interval and mortality in acute heart failure patients
Chan Soon Park, Hyun-Jai Cho, Eue-Keun Choi, Sang Eun Lee, Min-Seok Kim, Jae-Joong Kim, Jin-Oh Choi, Eun-Seok Jeon, Kyung-Kuk Hwang, Shung Chull Chae, Sang Hong Baek, Seok-Min Kang, Byungsu Yoo, Dong-Ju Choi, Youngkeun Ahn, Kye-Hoon Kim, Myeong-Chan Cho, Byung-Hee Oh, Hae-Young Lee
Korean J Intern Med. 2020;35(6):1371-1384. Published online May 8, 2020
Background/Aims: This study investigated the prognostic power of corrected QT (QTc) interval in patients with acute heart failure (AHF) according to sex.
Methods: We analyzed multicenter Korean Acute Heart Failure registry with patients with AHF admitted from 2011 to 2014. Among them, we analyzed 4..
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The mortality benefit of carvedilol versus bisoprolol in patients with heart failure with reduced ejection fraction
Ki Hong Choi, Ga Yeon Lee, Jin-Oh Choi, Eun-Seok Jeon, Hae-Young Lee, Sang Eun Lee, Jae-Joong Kim, Shung Chull Chae, Sang Hong Baek, Seok-Min Kang, Dong-Ju Choi, Byung-Su Yoo, Kye Hun Kim, Myeong-Chan Cho, Hyun-Young Park, Byung-Hee Oh
Korean J Intern Med. 2019;34(5):1030-1039. Published online October 16, 2018
Background/Aims: It is unknown whether different β-blockers (BBs) have variable effects on long-term survival of patients with heart failure with reduced ejection fraction (HFrEF). This study compares the effects of two BBs, carvedilol and bisoprolol, on survival in patients with HFrEF.
Methods: ..
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Current status and therapeutic considerations of hypertension in the elderly
Ju-Hee Lee, Kwang-Il Kim, Myeong-Chan Cho
Korean J Intern Med. 2019;34(4):687-695. Published online July 1, 2019
As the prevalence of hypertension in the elderly population is increasing, information regarding the characteristics, optimal blood pressure targets, and special considerations for elderly hypertensive patients is needed to improve clinical outcomes. Various factors should be considered when managin..
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