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Nephrology
Concomitant inhibition of renin angiotensin system and Toll-like receptor 2 attenuates renal
injury in unilateral ureteral obstructed mice
Sarah Chung, Jin Young Jeong, Yoon Kyung Chang, Dae Eun Choi, Ki Ryang Na, Beom Jin Lim, Kang Wook Lee
Korean J Intern Med. 2016;31(2):323-334. Published online February 26, 2016
Background/Aims: There has been controversy about the role of Toll-like receptor 2 (TLR2) in renal injury following ureteric obstruction. Although inhibition of the renin angiotensin system (RAS) reduces TLR2 expression in mice, the exact relationship between TLR2 and RAS is not known. The aim of th..
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Pretreatment with Darbepoetin Attenuates Renal Injury in a Rat Model of Cisplatin-Induced Nephrotoxicity
Dae Eun Choi, Jin Young Jeong, Beom Jin Lim, Kang Wook Lee, Young-Tai Shin, Ki-Ryang Na
Korean J Intern Med. 2009;24(3):238-246. Published online August 26, 2009
Background/AimsDarbepoetin alfa (DPO) exhibits comparable renoprotective effects to erythropoietin (EPO) in several animal models of acute renal injury. We examined whether DPO also attenuated renal injury in a rat model of cisplatin nephrotoxicity. Method.. </div>
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