Polymorphism in the promoter region of the klotho gene (G-395A) is associated with early dysfunction in vascular access in hemodialysis patients
Youngsu Kim, Sun Joo Jeong, Hyung Suk Lee, Eun Jung Kim, Young Rim Song, Sung Gyun Kim, Ji Eun Oh, Young Ki Lee, Jang Won Seo, Jong Woo Yoon, Ja-Ryong Koo, Hyung Jik Kim, Jung Woo Noh, Seung Ho Park
Korean J Intern Med. 2008;23(4):201-207. Published online December 30, 2008
Background/AimsVascular access dysfunction is an important cause of morbidity and mortality in hemodialysis (HD) patients. Recent studies have shown that a klotho gene mutation is related to endothelial dysfunction, thrombosis, and arteriosclerosis, which are ..
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