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Gastroenterology
Reduced risk of gastrointestinal bleeding associated with eupatilin in aspirin plus acid suppressant users: nationwide population-based study
Hyun Seok Lee, Ji Hyung Nam, Dong Jun Oh, Yeo Rae Moon, Yun Jeong Lim
Korean J Intern Med. 2024;39(2):261-271. Published online December 14, 2023
Background/Aims: Mucoprotective agents, such as eupatilin, are often prescribed to prevent gastrointestinal (GI) bleeding in addition to an acid suppressant despite the absence of a large-scale study. We evaluated the additional effect of eupatilin on the prevention of GI bleeding in both the upper ..
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The combined use of anti-peptic agents is associated with an increased risk of osteoporotic fracture: a nationwide case-control study
Dong Jun Oh, Ji Hyung Nam, Hyun Seok Lee, Yeo Rae Moon, Yun Jeong Lim
Korean J Intern Med. 2024;39(2):228-237. Published online February 7, 2024
Background/Aims: Long-term use of acid suppressants such as proton pump inhibitors (PPIs) and histamine 2 receptor antagonist (H2RA) has been associated with the risk of osteoporotic fracture. Acid suppressants and muco-protective agents (MPAs) are often used together as anti-ulcer agents. We evalua..
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Association between eupatilin and reduction in small bowel bleeding in aspirin users and aspirin plus acid suppressant users
Hyun Seok Lee, Ji Hyung Nam, Dong Jun Oh, Hyun Jung Ahn, Yun Jeong Lim
Korean J Intern Med. 2023;38(4):484-492. Published online May 19, 2023
Background/Aims: Capsule endoscopy (CE) has shown that low-dose aspirin occasionally causes small bowel (SB) bleeding. We herein evaluated the protective effects of mucoprotective agents (MPAs) on SB bleeding in aspirin users using the nationwide database of claims data from the National Health Insu..
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The effect of rebamipide on non-steroidal anti-inflammatory drug-induced gastro-enteropathy: a multi-center, randomized pilot study
Dong Jun Oh, Hyuk Yoon, Hyun Soo Kim, Yoon Jin Choi, Cheol Min Shin, Young Soo Park, Nayoung Kim, Dong Ho Lee, You-Jung Ha, Eun Ha Kang, Yun Jong Lee, Nayoung Kim, Ki-Jeoung Kim, Fei Liu
Korean J Intern Med. 2022;37(6):1153-1166. Published online November 1, 2022
Background/Aims: Non-steroidal anti-inflammatory drugs (NSAIDs) are commonly-used medications, and ailments such as arthritis or heart disease, require long-term use of these drugs, which can induce gastroenteropathy with bleeding and ulcers. This study investigated the associations between efficacy..
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