Original Article
Efficacy of Initial Treatment with Clevudine in Naive Patients with Chronic Hepatitis B
Hyeon Woong Yang, Byung Seok Lee, Tae Hee Lee, Heon Young Lee, Kwan Woo Nam, Young Woo Kang, Hee Bok Chae, Seok Hyun Kim, Seok Bae Kim, Hyang Ie Lee, An Na Kim, Il Han Song, Sae Hwan Lee, Hong Su Kim
Korean J Intern Med. 2010;25(4):372-376. Published online November 27, 2010
Background/AimsClevudine, a pyrimidine nucleoside analogue, has potent antiviral effects in patients with chronic viral hepatitis B (CHB). We report the efficacy of initial treatment with clevudine in naïve patients with CHB living in Daejeon and Chungcheong Province, South ..
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Original Article
Increased Expression of Cyclooxygenase-2 is Associated with the Progression to Cirrhosis
Soung Won Jeong, Jae Young Jang, Sae Hwan Lee, Sang Gyun Kim, Young Koog Cheon, Young Seok Kim, Young Deok Cho, Hong Soo Kim, Joon Seong Lee, So-Young Jin, Chan Sup Shim, Boo Sung Kim
Korean J Intern Med. 2010;25(4):364-371. Published online November 27, 2010
Background/AimsTo investigate the degree of cyclooxygenase-2 (COX-2) protein expression in chronic hepatitis and cirrhosis. MethodsCOX-2 protein expression was evaluated in 43 cases of chronic hepatitis and 24 cases of cirrhosis using immunohist..
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Original Article
Prevalence of Depression and Anxiety in Outpatients with Chronic Airway Lung Disease
Yon Ju Ryu, Eun-Mi Chun, Jin Hwa Lee, Jung Hyun Chang
Korean J Intern Med. 2010;25(1):51-57. Published online February 26, 2010
Background/AimsPatients with chronic airway lung diseases often experience depression and anxiety, but little information is available regarding Koreans with these conditions. We thus assessed depression and anxiety in Korean patients with chronic airway lung diseases.
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Review
Update on Endoscopic Treatment of Chronic Pancreatitis
Byung Moo Yoo, Glen A. Lehman
Korean J Intern Med. 2009;24(3):169-179. Published online August 26, 2009
Endoscopic therapy has been increasingly recognized as the effective therapy in selected patients with chronic pancreatitis. Utility of endotherapy in various conditions occurring in chronic pancreatitis is discussed. Its efficacy, limitations, and alternatives are addressed. For the best managem..
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Original Article
Relationship between serum brain natriuretic peptide and heart function in patients with chronic kidney disease
Jae Won Yang, Min Soo Kim, Jae Seok Kim, Jong Myoung Yoo, Seung Tae Han, Bi Ro Kim, Yun Deok Kim, Jeong Wook Choi, Seung Ok Choi, Byoung Geun Han
Korean J Intern Med. 2008;23(4):191-200. Published online December 30, 2008
Background/AimsBrain natriuretic peptide (BNP) levels are known to be elevated in patients with chronic kidney disease (CKD) and normal heart function. Therefore, the present study was performed to examine the effectiveness of BNP level in diagnosing heart failure in patients ..
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Original Article
Clinical findings of the patients with legal pulmonary disability - Short-term follow-up at a tertiary university hospital in Korea
Sun Young Kyung, Yu Jin Kim, Chang Hyeok An, Sang Pyo Lee, Jeong Woong Park, Sung Hwan Jeong
Korean J Intern Med. 2008;23(2):72-77. Published online June 20, 2008
Background/AimsLegal pulmonary disability in Korea is decided for chronic respiratory patients who have been diagnosed for a year or more, and the patients haven't gotten better after more than 2 months of sufficient treatment and they have shown no change in their pulmonary f..
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Original Article
Clinical Observation of 12 Farmers Who Believe Themselves to Have Suffered from Chronic Pesticide Intoxication
Zoong-Rock Hong, So-Young Hong, Mi-Jung Han, Hae-seung Lee, Hyo-Ook Gil, Jong-O Yang, En-Yung Lee, Sae-Yong Hong
Korean J Intern Med. 2008;23(1):1-4. Published online March 20, 2008
Background/AimsWe assessed twelve cases of suspected chronic pesticide intoxication, with medically unexplained physical symptoms. MethodsComplete blood cell count (CBC), blood chemistry, routine urinalysis, chest X-ray, ECG, ..
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Original Article
Hepatitis B Reactivation During Adjuvant Anthracycline-Based Chemotherapy in Patients with Breast Cancer: A Single Institution's Experience
Min Kyoung Kim, Jin Hee Ahn, Sung-Bae Kim, Young-Suk Im, Soon Im Lee, Sei-Hyun Ahn, Byung Ho Son, Gyungyub Gong, Hak-Hee Kim, Woo Kun Kim
Korean J Intern Med. 2007;22(4):237-243. Published online December 20, 2007
BackgroundThe objectives of this study were to determine the incidence, outcome and risk factors for HBV reactivation in HBsAg positive breast cancer patients while on anthracycline -based adjuvant chemotherapy. MethodsWe retr..
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Original Article
Diagnostic Usefulness of the Janus Kinase 2 Mutation in non BCR/ABL Myeloproliferative Disorders
Soo-Mee Bang, Jeong Yeal Ahn, Jiyoon Park, Soo Jin Yoo, Se Hoon Park, Eun Mi Nam, Pil Whan Park, Yiel Hea Seo, Eun Kyung Cho, Dong Bok Shin, Jae Hoon Lee
Korean J Intern Med. 2006;21(4):219-224. Published online December 31, 2006
BackgroundWe investigated the Janus kinase 2 (JAK2) mutation and its diagnostic value in patients suffering with non BCR/ABL myeloproliferative diseases (nMPD) or other reactive conditions. Methods..
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Case Report
A Case of Avascular Necrosis of the Femoral Head as Initial Presentation of Chronic Myelogenous Leukemia
Ji Yong Moon, Byung Su Kim, Hye Ryeon Yun, Jung Hye Choi, Young Yul Lee, In Soon Kim, Myung Ju Ahn
Korean J Intern Med. 2005;20(3):255-259. Published online September 30, 2005
Chronic myelogenous leukemia (CML) is a malignant clonal disorder of hemopoietic stem cells characterized by abnormal proliferation and accumulation of immature granulocyte. Leukostasis is one of the complications of CML and is characterized by partial or total occlusion of microcirculation by ag..
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