Pulmonology / Original Article
Chronic obstructive pulmonary disease (COPD) assessment test scores corresponding to modified Medical Research Council grades among COPD patients
Chang-Hoon Lee, Jinwoo Lee, Young Sik Park, Sang-Min Lee, Jae-Joon Yim, Young Whan Kim, Sung Koo Han, Chul-Gyu Yoo
Korean J Intern Med. 2015;30(5):629-637. Published online August 27, 2015
Background/Aims: In assigning patients with chronic obstructive pulmonary disease (COPD) to subgroups according to the updated guidelines of the Global Initiative for Chronic Obstructive Lung Disease, discrepancies have been noted between the COPD assessment test (CAT) criteria and modified Medical ..
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Cardiology / Original Article
Discordance between ambulatory versus clinic blood pressure according to global cardiovascular risk group
Jinho Shin, Sung Ha Park, Ju Han Kim, Sang Hyun Ihm, Kwang-il Kim, Woo Shik Kim, Wook Bum Pyun, Yu-Mi Kim, Sung-il Choi, Soon Kil Kim
Korean J Intern Med. 2015;30(5):610-619. Published online August 27, 2015
Background/Aims: The detection of white coat hypertension (WCH), treated normalized hypertension, and masked hypertension (MH) is important to improve the effectiveness of hypertension management. However, whether global cardiovascular risk (GCR) profile has any effect on the discordance between amb..
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Gastroenterology / Original Article
Can proton pump inhibitors reduce rebleeding following Histoacryl sclerotherapy for gastric variceal hemorrhage?
Ka Rham Kim, Chung Hwan Jun, Kyu Man Cho, Jin Woo Wi, Seon Young Park, Sung Bum Cho, Wan Sik Lee, Chang Hwan Park, Young Eun Joo, Hyun Soo Kim, Sung Kyu Choi, Jong Sun Rew
Korean J Intern Med. 2015;30(5):593-601. Published online August 27, 2015
Background/Aims: To evaluate the efficacy of proton pump inhibitors (PPIs) in reducing rebleeding and bleeding-related death rates after endoscopic gastric variceal obliteration (GVO) using N-butyl-2-cyanoacrylate (NBC).
Methods: This study enrolled 341 patients who were consecutively diagnosed wi..
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Rheumatology / Original Article
Quantitative analysis of nailfold capillary morphology in patients with fibromyalgia
Dug-Hyun Choi, Hyun-Sook Kim
Korean J Intern Med. 2015;30(4):531-537. Published online June 29, 2015
Background/Aims: Nailfold capillaroscopy (NFC) has been used to examine morphological and functional microcirculation changes in connective tissue diseases. It has been demonstrated that NFC patterns reflect abnormal microvascular dynamics, which may play a role in fibromyalgia (FM) syndrome. The ai..
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Gastroenterology / Original Article
Long-term efficacy of tenofovir disoproxil fumarate therapy after multiple nucleos(t)ide analogue failure in chronic hepatitis B patients
Hyo Jin Kim, Ju-Yeon Cho, Yu Jin Kim, Geum-Youn Gwak, Yong-Han Paik, Moon Seok Choi, Kwang Cheol Koh, Seung Woon Paik, Byung Chul Yoo, Joon Hyeok Lee
Korean J Intern Med. 2015;30(1):32-41. Published online December 30, 2014
Background/Aims: The efficacy of tenofovir disoproxil fumarate (TDF) for the treatment of chronic hepatitis B (CHB) patients following prior treatment failure with multiple nucleos(t)ide analogues (NAs) is not well defined, especially in Asian populations. In this study we investigated the efficacy ..
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Infectious diseases / Original Article
Kinetics of T-cell-based assays on cerebrospinal fluid and peripheral blood mononuclear cells in patients with tuberculous meningitis
Ki-Ho Park, Mi Suk Lee, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Joong Koo Kang, Sang-Ahm Lee, Sung-Han Kim
Korean J Intern Med. 2014;29(6):793-799. Published online October 31, 2014
Background/Aims: The goal of this study was to monitor tuberculosis (TB)-specific T-cell responses in cerebrospinal f luid-mononuclear cells (CSF-MCs) and peripheral blood mononuclear cells (PBMCs) in patients with tuberculous meningitis (TBM) over the course of anti-TB therapy.
Methods: Adult pati..
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Hemato-oncology / Review
Recent advances in treatment of aplastic anemia
Seung Hwan Shin, Sung Eun Lee, Jong Wook Lee
Korean J Intern Med. 2014;29(6):713-726. Published online October 31, 2014
Recent advances in the treatment of aplastic anemia (AA) made most of patients to expect to achieve a long-term survival. Allogeneic stem cell transplantation (SCT) from HLA-matched sibling donor (MSD-SCT) is a preferred first-line treatment option for younger patients with severe or very severe AA,..
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Cardiology / Review
Role of modern 3D echocardiography in valvular heart disease
Takahiro Shiota
Korean J Intern Med. 2014;29(6):685-702. Published online October 31, 2014
Three-dimensional (3D) echocardiography has been conceived as one of the most promising methods for the diagnosis of valvular heart disease, and recently has become an integral clinical tool thanks to the development of high quality real-time transesophageal echocardiography (TEE). In particular, fo..
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Pulmonology / Original Article
Factors predictive of the failure of medical treatment in patients with pleural infection
Sung-Kyoung Kim, Chul Ung Kang, So Hyang Song, Deog Gon Cho, Kyu Do Cho, Chi Hong Kim
Korean J Intern Med. 2014;29(5):603-612. Published online August 28, 2014
Background/Aims: The clinical outcomes of some patients with pleural infection may be favorable with medical treatment alone, but in others, the disease progresses and requires additional surgical treatment. However, little is known about the factors affecting this difference. The aim of this study ..
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Nephrology / Original Article
Effects of pretransplant plasmapheresis and rituximab on recurrence of focal segmental glomerulosclerosis in adult renal transplant recipients
Hoon Suk Park, Yuah Hong, In O Sun, Byung Ha Chung, Hyung Wook Kim, Bum Soon Choi, Cheol Whee Park, Dong Chan Jin, Yong Soo Kim, Chul Woo Yang
Korean J Intern Med. 2014;29(4):482-488. Published online June 27, 2014
Background/Aims: Recurrent focal segmental glomerulosclerosis (FSGS) following renal transplantation is relatively common. However, the risk factors and optimal pretransplant treatment preventing recurrence of FSGS remain controversial.
Methods: We retrospectively reviewed 27 adult renal transplan..
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Gastroenterology / Original Article
Clinical outcomes of gastric variceal obliteration using N-butyl-2-cyanoacrylate in patients with acute gastric variceal hemorrhage
Chung Hwan Jun, Ka Rham Kim, Jae Hyun Yoon, Han Ra Koh, Won Suk Choi, Kyu Man Cho, Sung Uk Lim, Chang Hwan Park, Young Eun Joo, Hyun Soo Kim, Sung Kyu Choi, Jong Sun Rew
Korean J Intern Med. 2014;29(4):437-444. Published online June 27, 2014
Background/Aims: To evaluate the long-term efficacy and safety of endoscopic injection of N-butyl-2-cyanoacrylate (NBC; Histoacryl) for treatment of bleeding gastric varices.
Methods: We retrospectively analyzed the records of 455 patients with gastric variceal hemorrhage (GVH) who were consecutiv..
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Case Report
Cryptococcal meningitis in a patient with chronic hepatitis C treated with pegylated-interferon and ribavirin
Tae-Hee Lee, Kee-Ook Lee, Yong-Seok Kim, Sun-Moon Kim, Kyu-Chan Huh, Young-Woo Choi, Young-Woo Kang
Korean J Intern Med. 2014;29(3):370-374. Published online April 29, 2014
Various adverse events have been reported during combination therapy with pegylated (PEG)-interferon-α and ribavirin, although opportunistic infections, especially cryptococcal meningitis, are very rare. A 61-year-old woman complained of headaches and a fever during treatment of a chronic hepatiti..
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Infectious diseases / Original Article
Third-generation cephalosporin resistance of community-onset Escherichia coli and Klebsiella pneumoniae bacteremia in a secondary hospital
Shinwon Lee, Seung Woo Han, Kun Woo Kim, Do young Song, Ki Tae Kwon
Korean J Intern Med. 2014;29(1):49-56. Published online January 2, 2014
Background/Aims: To enable appropriate antimicrobial treatment for community-
onset infections in emergency departments (EDs), data are needed on the
resistance profiles of Escherichia coli and Klebsiella pneumoniae, which are the main
pathogens of community-onset bacteremia.
Methods: Records we..
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Case Report
Two dislodged and crushed coronary stents: treatment of two simultaneously dislodged stents using crushing techniques
Dong-Hyeok Yang, Seong-Ill Woo, Dae-Hyeok Kim, Sang-Don Park, Ji-Hun Jang, Jun Kwan, Sung-Hee Shin
Korean J Intern Med. 2013;28(6):718-723. Published online October 29, 2013
Coronary stent dislodgement is a rare complication of percutaneous coronary intervention. We report a rare case of dislodgement of two intracoronary stents. On withdrawal of two balloon catheters, one with a guide wire was mechanically distorted from the left main (LM) to the proximal left anteri..
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Case Report
Successful coronary stent retrieval from the ascending aorta using a gooseneck snare kit
Ji-Hun Jang, Seong-Ill Woo, Dong-Hyeok Yang, Sang-Don Park, Dae-Hyeok Kim, Sung-Hee Shin
Korean J Intern Med. 2013;28(4):481-485. Published online July 1, 2013
Coronary stent dislodgement is a rare complication of percutaneous coronary intervention. We report a case of stent dislodgement in the ascending thoracic aorta. The stent was mechanically distorted in the left circumflex artery (LCX) while being delivered to the proximal LCX lesion. The balloon ..
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Pulmonology / Original Article
The start of chemotherapy until the end of radiotherapy in patients with limited-stage small cell lung cancer
Kyoung Ju Lee, Eun Joo Lee, Gyu Young Hur, Sang Yeub Lee, Je Hyeong Kim, Chol Shin, Jae Jeong Shim, Kwang Ho In, Kyung Ho Kang, Se Hwa Yoo, Sung Yong Lee
Korean J Intern Med. 2013;28(4):449-455. Published online July 1, 2013
Background/AimsChemotherapy combined with radiation therapy is the standard treatment for limited stage small cell lung cancer (LS-SCLC). Although numerous studies indicate that the overall duration of chemoradiotherapy is the most relevant predictor of outcome, the optimal ch..
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Case Report
Synephrine-containing dietary supplement precipitating apical ballooning syndrome in a young female
Hyemoon Chung, Sung Woo Kwon, Tae Hoon Kim, Ji Hyun Yoon, Dae Won Ma, Yoo Mi Park, Bum-Kee Hong
Korean J Intern Med. 2013;28(3):356-360. Published online May 1, 2013
Apical ballooning syndrome (ABS) is a unique reversible cardiomyopathy that is frequently precipitated by emotional or physical stress. In addition, the few drugs reported to precipitate ABS were either illegal or strictly controlled for medical use. This paper reports a case of ABS precipitated ..
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Endocrinology-metabolism / Original Article
Elevated thyroid stimulating hormone levels are associated with metabolic syndrome in euthyroid young women
Jee-Young Oh, Yeon-Ah Sung, Hye Jin Lee
Korean J Intern Med. 2013;28(2):180-186. Published online February 27, 2013
Background/AimsThe existence of an association between thyrotropin (thyroid stimulating hormone, TSH) levels and metabolic derangement in euthyroid subjects is controversial. We examined the association between high normal TSH levels and metabolic syndrome in healthy young wom..
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Original Article
The Causes and Treatment Outcomes of 91 Patients with Adult Nosocomial Meningitis
Hye-In Kim, Shin-Woo Kim, Ga-Young Park, Eu-Gene Kwon, Hyo-Hoon Kim, Ju-Young Jeong, Hyun-Ha Chang, Jong-Myung Lee, Neung-Su Kim
Korean J Intern Med. 2012;27(2):171-179. Published online May 31, 2012
Background/AimsFrequent pathogens of nosocomial meningitis were investigated and the adequacy of empiric antibiotic therapy was assessed. Outcomes of nosocomial meningitis were also evaluated. MethodsNinety-one patients, who were diagnosed and t..
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